Development of an exposure assessment for the risk of bladder cancer from aromatic amines and evaluation of the effect of bladder cancer disease on employment

Project No. FF-FB 0286




The aim of the scientific project is to achieve a consensus in collaboration between occupational physicians and urologists, in which an orientation dose for carcinogenic aromatic amines is recommended, which can be assessed as relevant or causal for the development of job-related urothelial tumors.

This consensus is relevant (a) for experts as well as for social courts and (b) for the processing and pension committees of the accident insurance agencies, which have to determine the causality of low exposure to carcinogenic aromatic amines in the development of cancer of the urinary tract and to assess their impact on the general job market.

Furthermore, in this project statements about relevant effects on working life due to illness and treatment of urothelial tumors caused by job-related exposure to carcinogenic aromatic amines or polycyclic aromatic hydrocarbons should be made.


A literature review on the subject "Exposure assessment of aromatic amines with regard to the risk of bladder cancer" is created. For this purpose, publications from PubMed, Web of Science and EMBASE databases as well as German-language publications on the BK 1301 are independently viewed and evaluated by two scientists. Data and information from relevant work are extracted. The results are discussed in a workshop with occupational physicians and urologists, further research needs may be shown and a consensus sought. Missing aspects are supplemented, the literature search expanded accordingly, and a recommendation on an orienting dose of carcinogenic aromatic amines as well as statements about the relevant effects of illness and treatment on working life made in circulation. The results will be published in a corresponding publication.

Last Update:



Financed by:
  • Deutsche Gesetzliche Unfallversicherung e. V. (DGUV)
Research institution(s):
  • Friedrich-Alexander-Universität Erlangen-Nürnberg

-cross sectoral-

Type of hazard:

dangerous substances


occupational disease, carcinogenic substances, legal provisions

Description, key words:

urothelial Tumors, bladder Cancer, carcinogene