Animal experiment (rat, intratracheal application) and in-vitro-test (rat lung epithelia cells).
Quartz effects may be not directly genotoxic and there could be a no-adverse effect level for cancerogenity. Biological activity of quartz in mixed dusts from workplaces can be completely different from pure quartz.
-cross sectoral-Type of hazard:
Toxikologie, Krebserregende Stoffe, MessverfahrenDescription, key words:
Biological activity of quartz in dusts from workplaces depends from work/workplace - specific parameters, such as crystalline silica content, surface properties of dust particles, other minerals. Assessment of quantity and classification of toxicological potential of quartz dust compounds versus pure quartz