Publicationlist Prof. Brüning

* = Medline/WOS IF: Impact Factor (2022)

771. *Köhler C, Schork K, Turewicz M, Eisenacher M, ..., Brüning T,; Käfferlein HU. Use of multiple machine learning approaches for selecting urothelial cancer-specific DNA methylation biomarkers in urine. IJMS 2024; 25: IF: 5.600 DOI: 10.3390/ijms25020738

770. *Ebert KE, Belov VN, John M, Weiß T, Brüning T, Hayen H, Koch HM, Bury D. Identification, organic synthesis, and sensitive snalysis of a cis-homosalate-specific exposure biomarker. Chem Res Toxicol 2024; Online ahead of Print IF: 4.100 DOI: 10.1021/acs.chemrestox.3c00287

769. *Olsson A, Bouaoun L, Schüz J, Vermeulen R, Behrens T, ..., Straif K, Brüning T, Vlaanderen J, Peters S. Lung Cancer Risks Associated with Occupational Exposure to Pairs of Five Lung Carcinogens: Results from a Pooled Analysis of Case-Control Studies (SYNERGY). Environ Health Perspect 2024; 132: 17005 IF: 10.200DOI: 10.1289/EHP13380

768. *Wan W, Peters S, Portengen L, Olsson A, ..., Behrens T, Brüning T, Kendzia B, ...Straif K, Kromhout H, Vermeulen R. Occupational Benzene Exposure and Lung Cancer Risk: A Pooled Analysis of 14 Case-Control Studies. Am J Respir Care Med 2024; 209: 185-196 IF: 24.700 DOI: 10.1164/rccm.202306-0942OC

767. *Wrobel S, Koslitz S, Bury D, Hayen H, Koch HM, Käfferlein HU, Brüning T, Käfferlein HU. Human biomonitoring of neonicotinoid exposures: case studies after the use of a spray-agent to ornamental plants and a topical medication to pets. Front Public Health 2024; 11: 1321138 IF: 5.200 DOI: 10.3389/fpubh.2023.1321138

766. *Weber DG, Casjens S, Wichert K, Lehnert M, Taeger D, Rihs HP, Brüning T, Johnen G, MoMar Study Group. Tasks and Experiences of the Prospective, Longitudinal, Multicenter MoMar (Molecular Markers) Study for the Early Detection of Mesothelioma in Individuals Formerly Exposed to Asbestos Using Liquid Biopsies. Cancers 2023; 15: 5896 IF: 5.200 DOI: 10.3390/cancers15245896

765. *Koslitz S, Heinrich B, Käfferlein HU, Koch HM, Pelzl T, Pitzke K, Köster D, Weiß T, Harth V, Brüning T, Behrens T, Taeger D. Biomonitoring of polycyclic aromatic hydrocarbons in firefighters at fire training facilities and in employees at respiratory protection and hose workshops. Front Public Health 2023; 11: 1277812 IF: 5.200 DOI: 10.3389/fpubh.2023.1277812

764. *Wrobel S, Bury D, Koslitz S, Hayen H, Koch HM, Brüning T, Käfferlein HU. Quantitative Metabolism and Urinary Elimination Kinetics of Seven Neonicotinoids and Neonicotinoid-Like Compounds in Humans. Environ Sci Technol 2023 Online ahead of Print IF: 11.400 DOI: 10.1021/acs.est.3c05040

763. *Wichert K, Hoppe R, Ickstadt K, Behrens T, ...., Easton D, Brüning T, Brauch H, Harth V, Rabstein S. Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer. Eur J Epidem 2023; 38: 1053-1068 IF: 13.600 DOI: 10.1007/s10654-023-01048-7

762. *Monsé C, Merget R, Bünger J, Pallapies D, Brüning T. Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed? Arch Toxicol 2023; 97: 2813-2818 IF: 6.100 DOI:10.1007/s00204-023-03567-4

761. Fartasch M, Gina M, Brüning T. Aktualisierung der Definition der Feuchtarbeit in der neuen TRGS 401. Dermatol Beruf Umwelt 2023; 71: 18-20 DOI: 10.5414/DBX00447

760. *Bury D, Weber T, Ebert K, Zülz S, Brüning T, Koch HM, Kolossa-Gehring M. Increasing Exposure to the UV Filters Octocrylene and 2-Ethylhexyl salicylate in Germany from 1996 to 2020: Human Biomonitoring in 24-h urine samples of the German Environmental Specimen Bank (ESB). Environ Int 2023; 182: 108334 IF: 11.4000 DOI: 10.1016/j.envint.2023.108334

759. *Brik A, Wichert K, Weber DG, Szafranski K, Rozynek P, Meier S, Ko YD, Büttner R, Gerwert K, Brüning T. Assessment of MYC and TERT copy number variations in lung cancer using digital PCR. BMS Res Notes 2023; 16: 279 IF: 1.800 DOI: 10.1186/s13104-023-06566-x

758. *Kespohl S, Warfolomeow I, Merget R, Brüning T, Raulf M. Hypersensitivity pneumonitis due to metal working fluids: detection of specific IgG antibodies to microbial antigens. Respir Physiol Neurol 2023; 315: 104107 IF: 2.300 DOI: 10.1016/j.resp.2023.104107

757. *van Kampen V, Marek E, Sucker K, Jettkant B, Kendzia B, Strauß B, Ulbrich M, Deckert A, Berresheim H, Eisenhawer C, Hoffmeyer F, Weidhaas S, Behrens T, Brüning T, Bünger J. Influence of face masks on the subjective impairment at different physical workloads. Sci Rep 2023; 13: 8133 IF: 4.600 DOI: 10.1038/s41598-023-34319-0

756. *Marek EM, van Kampen V, Jettkant B, Kendzia B, Strauß B, Ulbrich M, Deckert A, Berresheim H, Eisenhawer C, Hoffmeyer F, Weidhaas S, Behrens T, Brüning T, Bünger J. Effects of wearing different face masks on cardiopulmonary performance at rest and exercise in a partially double-blinded randomized cross-over study. Sci rep 2023; 13: 6950 IF: 4.600 DOI: 10.1038/s41598-023-32180-9

755. * Rihs HP, Casjens S, Raiko I, Kollmeier J, Lehnert M, Nöfer K, May-Taube K, Kaiser N, Taeger D, Behrens T, Brüning T, Johnen G. Mesothelin gene variants affect soluble mesothelin-related protein levels in the plasma of asbestos-exposed males and mesothelioma patients from Germany. Biology 2022; 11: 1826 DOI: 10.3390/biology111

754. *Lindström S, Wang L, Feng H, ...., Pasanius´c B, Kraft P. Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions. J Natl Cancer Inst 2023; 115: 712-732 IF: 13.757 DOI: 10.1093/jnci/djad043

753. *Gina M, Wichert K, Pieper B, Brüning T, Fartasch M. Irritatant potential of different washing procedures used for heavy-duty soiling: short and intense or longer and mild? Contact Dermatitis 2023; 88: 363-371 IF: 5.500 DOI: 10.1111/cod.14282

752.* Gina M, Wichert K, Kutz G, Brüning T, Fartasch M. Applying skin protective cream and the wearing of gloves? - a randomised controlled experimental study. Contact Dermatitis 2023; 88: 372-382 IF: 5.500 DOI:10.1111/cod.14287

751. *Koppisch D, Zschiesche W, Goebel A, Schlatter S, von Mering Y, Ellegast R, Van Gelder R, von der Heyden T, Pallapies D, Behrens T, Eisenhawer C, Brüning T. Schweißrauchexpositionen in Deutschland und Bewertung der gesundheitsschädigenden Wirkungen – insbesondere im Hinblick auf Lungenkrebserkrankungen. Arbeitsmedizin Sozialmedizin Umweltmedizin 2023; 58: 185-195 doi: 10.17147/asu-1-257912

750. *Taeger D, Koslitz S, Käfferlein HU, Pelzl T, Heinrich B, Breuer D, Weiß T, Harth V, Behrens T, Brüning T. Exposure to polycyclic aromatic hydrocarbons assessed by biomonitoring of firefighters during fire operations in Germany. Int J Hyg Environ Health 2023; 114110 IF: 6.000 DOI 10.1016/j.ijheh.2023.114110

2022

749. *Ebert KE, Griem P, Weiß T, Brüning T, Hayen H, Koch HM, Bury D. Diastereoselective metabolism of homomenthyl salicylate (homosalate): Identification of relevant human exposure biomarkers. Environ Int 2022; 170: 107637 IF: 11.800 DOI: 10.1016/j.envint.2022.107637

748.*Connolly A, Koch HM, Bury D, Koslitz S, Kolossa-Gehring M, Conrad A, Murawski A, McGrath JA, Leahy M, Brüning T, Coggins MA. A human biomonitoring study assessing Glyphosate and Aminomethylphosphonic Acid (AMPA) exposures among farm and non-farm families. Toxics 2022; 10: 11 IF: 4.600 DOI: 10.3390/toxics10110690

747. *Manoochehri M, Borhani N, Gerhäuser C,..., Brüning T, Brauch H, Ko Y-D, Hamann U. DNA methylation biomarkers for non-invasive detection of triple negative breast cancer using liquid biopsy. Int J Cancer 2023; 152: 1025-1035 IF: 6.400 DOI:10.1002/ijc.34337

746. *Jimenez-Ramirez C, Weber DG, Agular-Madrid G, Brik A, ...Casjens S, Raiko I, Brüning T, Johnen G, Cabello-Lopez A. Assessment of miR-103a-3p in leukocytes-No diagnostic benefit in combination with the blood-based biomarkers mesothelin and calretinin for malignant pleural mesothelioma diagnosis. PLosOne 2022; 17: e0275936 IF: 3,700 DOI: 10.1371/journal.pone.0275936

745. *Ahearn TU, Zhang H, ... Brüning T, ..., Schmidt MK, Garcia-Closas M, Chatterjee N. Common variants in breast cancer risk loci predispose to distinct tumor subtypes. Breast Cancer Res 2022; 24: 2 IF: 7.400 DOI: 10.1186/s13058-021-01484-x

744. *Bünger J, Marek EM, van Kampen V, Brüning T. Efficiency and burdens of wearing masks for protection against SARS-CoV-2: A narrative review focused on the current situation at workplaces. Res & Rev Health Care 2022; 7: RRHOAJ.MS.ID.000266

743. *Bracht T, Kleefisch D, ..., Hovanec J, Johnen G, Meier S, Ko YD, Behrens T, Brüning T, ..., Sitek M. Plasma Proteomics Enable Differentiation of Lung Adenocarcinoma from Chronic Obstructive Pulmonary Disease (COPD). IJMS 2022; 23: 11242 IF: 3.600 DOI: 10.3390/ijms231911242

742. *Behrens T, Ge C, Vermeulen R, Kendzia B, Olsson A, Schüz J, Kromhout H, Pesch B, ..., Straif K, Brüning T. Occupational exposure to nickel and hexavalent chromium and the risk of lung cancer in a pooled analysis of case-control studies (SYNERGY). Int J Cancer 2023; 152: 645-660. IF: 6.400 DOI: 10.1002/ijc.34272

741. *Ringbeck B, Bury D, Lee I, Lee G, Alakeel R, Alrashed M, Tosepu R, Jayadipraja EA, Tantrakarnapa K, Kliengshuay W, Brüning T, Choi K, Koch HM. Biomarker-determined Nonylphenol exposure and associated risks in children of Thailand, Indonesia, and Saudi Arabia. Environ Sci Technol 2022; 56: 10229-10238 IF: 11.400 DOI: 10.1021/acs.est.2c01404

740. Brüning T, Sucker K. Arbeitsplatzgrenzwerte für Stoffe mit einer Reiz- und Geruchswirkung. ASU 2022; 57: 448-445 DOI: 10.17147/asu-1-204767

739. *Casjens S, Taeger D, Tisch A, Brenscheidt F, Beermann B, Brüning T, Behrens T, Rabstein S. Investigating the influence of shift work rosters on stress measured as cortisol in hair during the SARS-CoV-2 pandemic. Psychoneuroendocrinol 2022; 143: 105858 IF:4.693 DOI: 10.1016/j.psyneuen.2022.105858

738. *Monsé C, Westphal G, Raulf M, Jettkant B, van Kampen V, Kendzia B, Schürmeyer L, Seifert E, Marek EM, Wiegand F, Rosenkranz N, Wegener C, Merget R, Brüning T, Bünger J. No inflammatory effects after acute inhalation of barium sulfate particles in human volunteers. BMC Pulm Med 22; 22: 233. IF: 3.100 DOI: 10.1186/s12890-022-02021-y

737. *Gleichenhagen J, Arndt C, Casjens S, Töpfer C, Gerulis H, Raiko I, Taeger D, Ecke T, Brüning T, Johnen G. Exploring solid-phase proximity ligation assay for survivin detection in urine. PLoS ONE 2022; 17: e0270535. IF: 3.700 DOI: 10.1371/journal.pone.0270535

736. *Casjens S, Taeger D, Brüning T, Behrens T. Altered mental distress among employees from different occupational groups and industries during the COVID-19 pandemic in Germany. J Occup Environ Med 2022; 64: 874-880 IF: 3.200 DOI: 10.1097/JOM.0000000000002595

735. *Taeger D, Wichert K, Lehnert M, Casjens S, Pesch B, Weber DG, Brüning T, Johnen G, Behrens T. Lung cancer and mesothelioma risks in a prospective cohort of workers with asbestos-related lung or pleural diseases. Am J Ind Med 2022; 65: .652-659 IF: 3.500 DOI: 10.1002/ajim.23401

734. *Wang X, Kapoor P, Auer Pl, Dennis J, Dunning AM, ...Brüning T, ..., Milne RL, Kraft P, Chang-Claude J, Lindström S. Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women. Sci Rep 2022; 12: 6199 IF: 4.600 DOI: 10.1038/s41598-022-10121-2

733. *Ringbeck B, Bury D, Ikeda-Araki A, Ait Bamai Y, Ketema RM, Miyashita C, Brüning T, Kishi R, Koch HM. Nonylphenol exposure in 7-year-old Japanese children between 2012 and 2017- Estimation of daily intakes based on novel urinary metabolites. Environ Int 2022; 161: 161: 107145 IF: 11.800 DOI: 10.1016/j.envint.2022.107145

732. *Ringbeck B, Belov V, Schmidtkunz C, Küpper K, Gries W, Weiß T, Brüning T, Hayen H, Bury D, Leng G, Koch HM. Human metabolism and urinary excretion kinetics of nonylphenol in three volunteers after a single oral dose. Chem Res Toxicol 2022; 34: 2392-2403 IF: DOI: 10.1021/acs.chemrestox.1c00301

731. *Olsson A, Guha N, Bouaoun L, Kromhout H, Peters S, Siemiatycki J, Ho V, Gustavsson P, Boffetta P, Vermeulen R, Behrens T, Brüning T, ... Schüz J, Straif K. Occupational exposure to polycyclic aromatic hydrocarbons and lung cancer risk: results from a pooled analysis of case-control studies (SYNERGY). Cancer Epidemiol Biomarkers Prev 2022; 31; 1433-1441 IF: 3.800 DOI: 10.1158/1055-9965.EPI-21-1428

730. *Hovanec J, Weiß T, Koch HM, Pesch B, Behrens T, Kendzia B, Arendt M, Dragano N, Moebus S, Schmidt B, Brüning T, Jöckel KH. Smoking intensity and urinary nicotine metabolites by socioeconomic status in the Heinz Nixdorf Recall study. BMC Public Health 2022; 22: 302 IF: 4.500 DOI: 10.1186/s12889-022-12609-y

729. *Gamrad-Streubel L, Haase LM, Rudolph K, Rühle K, Bachand AM, Crawford L, Mundt K, Bünger J, Pallapies D, Taeger D, Casjens S, Molkenthin A, Neumann S, Brüning T, Birk T. Underground salt and potash workers exposed to nitrogen oxides and diesel exhaust: assessment of specific effect biomarkers. Int Arch Occup Environ Health 2022; 95: 1817-1828 IF: 3.000 DOI: 10.1007/s00420-022-01876-2

728. *Gambichler T, Finis C, Abu Rached N, Scheel CH, Becker JC, Käfferlein HU, Brüning T, Abolmaali N, Susok L. Expression of DNA mismatch repair proteins in melanoma patients treated with immune checkpoint inhibitors. J Canc Res Clin Onc 2022; 149. 1241-1247. IF: 3.600 DOI: 10.1007/s00432-022-04002-4

727. *Burek K, Rabstein S, Kantermann T, Vetter C, Rotter M, Wang-Sattler R, Lehnert M, Pallapies D. Jöckel KH, Brüning T, Behrens T. Night work, chronotype and cortisol at awakening in female hospital employees. Sci Rep 2022; 12: 6525 IF: 4.600 DOI: 10.1038/s41598-022-10054-w

726. *Taeger D, Wichert k, Lehnert M, Casjens S, Pesch B, Weber DG, Brüning T, Johnen G, Behrens T. Lung cancer and mesothelioma risks in a prospective cohort of workers with asbestos-related lung or pleural diseases. Am J Ind Med 2022; Online ahead of Print IF: 3.500 DOI: 10.1002/ajim.23401

725. *Mavaddat N, Dorling L, Carvalho S, Allen J, ....., Brüning T, ....Schmidt M, Easton DF. Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes. JAMA Oncology 2022; 8: e216744 IF: 28.400 DOI: 10.1001/jamaoncol.2021.6744

724. *Sander I, Kespohl S, Zahradnik E, Göcke P, Hosbach I, Herrmann BL, Brüning T, Raulf M. Quantitative measurement of IgG to SARS‐CoV‐2 antigens using monoclonal antibody‐based enzyme‐linked immunosorbent assays. Clin & Trans Imm 2022; 11 IF: 5.800 DOI: 10.1002/cti2.1369

723. *Casjens S, Brenscheidt F, Tisch A, Beermann B, Brüning T, Behrens T, Rabstein S. Social jetlag and sleep debts are altered in different rosters of night shift work. PLoS ONE 2022; 17: e0262049 IF: 3.700 10.1371/journal.pone.0262049

722. * Bauer A, Siegrist K, Wolff M, Nield L, Brüning T, Upham BL, Käfferlein HU, Plöttner S. The Carcinogenic Properties of Overlooked yet Prevalent Polycyclic Aromatic Hydrocarbons in Human Lung Epithelial Cells. Toxics 2022; 10: 28 IF: 4.600 DOI: 10.3390/toxics10010028

721. *Ahearn T, Zhang H, Michailidou K, ...., Brüning T, ...., Garcia-Closas M, Chatterjee N. Common variants in breast cancer risk loci predispose to distinct tumor subtypes. Breast Cancer Res 2022; 24: 1 IF: 7.400 DOI: 10.1186/s13058-021-01484-x

720. * Wrobel SA, Bury D, Hayen H, Koch HM, Brüning T, Käfferlein HU. Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages.
Arch Toxicol 2022; 96: 121-134 IF: 6.100 DOI: 10.1007/s00204-021-03159-0

719. *Manoocchehri M, Hielscher T, Borhani N, Gerhäuser C, Fletcher O, Swerdlov A, Ko YD, Brauch H, Brüning T, Hamann U. Epigenetic quantification of circulating immune cells in peripheral blood of triple-negative breast cancer patients. Clin Epigenetics 2021; 13: 207 IF: 5.700 DOI: 10.1186/s13148-021-01196-1

718 *Behrens T, Burek K, Rabstein S, Wichert K, Erbel R, Eisele L, Arendt M, Dragano N, Brüning T, Jöckel KH. Impact of shift work on the risk of depression. Chronobiol Int 2021; 38: 1761-1775 IF: 2.800 DOI: 10.1080/07420528.2021.1962903

717. *Morra A, Escala-Garcia M, .....Brüning T, ...., Easton DF, Chevenx-Trench G, Schmidt MK. Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
Breast Canc Res 2021; 23: 86 IF: 7.400 DOI: 10.1186/s13058-021-01450-7

716. *Maniscalco J, Hoffmeyer F, Monsé , Jettkant B, Marek EM, Brüning T, Bünger J, Sucker K. Physiological responses, self-reported health effects, and cognitive performance during exposure to carbon dioxide at 20 000 ppm.
Indoor Air 2022, 32: e12939 IF: 5.800 DOI: 10.1111/ina.12939

715. *Lehnert M, Goebel A, Zschiesche W, Kendzia B, Pelzer J, Taeger D, Brüning T, Behrens T. How to reduce the exposure of welders to an acceptable level: Results of the InterWeld study.
Ann Work Exp Healh 2022; 66: 192-202 IF: 2.600 DOI: 10.1093/annweh/wxab082

2021

714. *Gambichler T, Ganjuur N, Tannapfel A, Vogt M, Scholl L, Abu Rached N, Bruckmüller S, Skrygan M, Becker JC, Käfferlein HU, Brüning T, Lang K. Mismatch Repair Protein Expression and Microsatellite Instability in Cutaneous Squamous Cell Carcinoma.
Current Oncol 2021; 28: 3316-3322 IF: 2.600 DOI: 10.3390/curroncol28050287

713. *Ebert K, Belov V, Weiß T, Brüning T, Hayen H, Koch HM, Bury D. Determination of urinary metabolites of the UV filter homosalate by online-SPE-LC-MS/MS. Analytica Chimica Acta 2021; 1176: 33874 IF: 6.200 DOI: 10.1016/j.aca.2021.338754

712. Casjens S, Behrens T, Brüning T, Taeger D. Studie zur Umsetzung und Akzeptanz des SARS-CoV-2 Arbeitsschutzstandards und der SARS-CoV-2-Arbeitsschutzregel für einen erfolgreichen Infektionsschutz im Unternehmen. ASU 2021; 56: 638-643

711. *Behrens T, Burek K, Rabstein S, Wichert K, Eberl R, Eisele L, Arendt M, Dragano N, Brüning T, Jöckel KH. Impact on shift work on the risk of depression. Chronobiol Int 2021; 38: 1761-1775 IF: 2.800 DOI: 10.1080/07420528.2021.1962903

710. *Ackar L, Casjens S, Andreas A, Raiko I, Brüning T, Geffken M, peine S, Kollmeier J, Johnen G, Bartkowiak K et al. Blood-based detection of lung cancer using cysteine-rich angiogenic inducer 61 (CYR61) as a circulating protein biomarker: a pilot study.
Molecular Oncology 2021; 15: 2877-2890 IF: 6.600 DOI: 10.1002/1878-0261.13099

709. Casjens S, Brüning T, Taeger D. Das Krebsrisiko von Feuerwehrleuten. Arbeitsmedizin Sozialmedizin Umweltmedizin 2021; 56: 359-366

708. *van Kampen V, Mertens H, Brüning T, Merget R
Serial measurements of fractional exhaled nitric oxide at home and at work: A useful tool for monitoring workers with platinum salt allergy after exposure reduction.
Health Sci Rep. 2021; 4: e299. eCollection 2021 Jun. DOI: 10.1002//hsr2.299.

707. *Ringbeck B, Bury D, Hayen H, Weiss T, Brüning T, Koch HM.
Determination of specific urinary nonylphenol metabolites by online-SPE-LC-MS/MS as novel human exposure biomarkers.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021;: 1177:122794. IF: 1.911 DOI: 10.1016/jchromb.2021.122794

706. *Gambichler T, Abu Rached N, Tannapfel A, Becker JC, Vogt M, Skrygan M, Wieland U, Silling S, Susok L, Stücker M, Meyer T, Stockfleth E, Junker K, Kaefferlein HU, Brüning T, Lang K. Expression of Mismatch Repair Proteins in Merkel Cell Carcinoma.
Cancers 2021; 21; 13:2524. IF: 5.200 DOI: 10.3390/cancers13112524

705. *Goertzen N, Pappesch R, Fassunke J, Brüning T, Ko YD, Schmidt J, Großerueschkamp F, Buettner R, Gerwert K.
Quantum cascade laser-based infrared imaging as a label-free and automated approach to determine mutations in lung adenocarcinoma.
Am J Pathol. 2021; 191: 1269-1280 IF: 6.000 DOI: 10.1016/j.ajpath.2021.04.013

704. *Monsé C, Hagemeyer O, van Kampen V, Raulf M, Weiss T, Menne E, Jettkant B, Kendzia B, Merget R, Brüning T, Bünger J.
Human Inhalation Study with Zinc Oxide: Analysis of Zinc Levels and Biomarkers in Exhaled Breath Condensate.
Adv Exp Med Biol 2021; 1324; 83-90. IF: 3.650 DOI: 10.1007/5584_2020_572

703. *Hovanec J, Siemiatycki J, Conway DI, Olsson A, Guenel P, Luce D, Jöckel KH, Pohlabeln H, Ahrens W, ...., Kromhout H, Vermeulen R, Boffetta P, Straif K, Schüz J, Casjens S, Pesch B, Brüning T, Behrens T. Application of two job indices for general occupational demands in a pooled analysis of case-control studies on lung cancer.
Scand J Work Environ Health 2021; 47: 475-481 IF: 6.300 DOI: 10.5271/sjweh.3967

702. *Aigner C, Brüning T, Eberhardt W, Härter M, Kaelberlah HP, Metzenmacher M, Shah R, Taube C, Thomas C.
Die aktuelle Therapie des asbestassoziierten malignen Pleuramesothelioms – Ein Experten-Konsensuspapier.
Pneumologie 2021; 75: 776-794 IF: 1.200 DOI: 10.1055/a-1404-1562

701. *Ringbeck B, Bury D, Gotthardt A, Hayen H, Otter R, Weiß T, Brüning T, Koch HM.
Human metabolism and urinary excretion kinetics of di-n-butyl adipate (DnBA) after oral and dermal administration in three volunteers.
Toxicol Lett 2021; 343: 11-20 IF: IF: 3.500 DOI: 10.1016/j.toxlet.2021.02.012

700. *Monsé C, Vossen K, Martiny A, Kirchner M, Dragan G, Jettkant B, Bünger J, Brüning T, Emmel C.
Comparative nitrogen oxide measurements in the IPA exposure laboratory. Gefahrstoffe Reinhaltung der Luft 2020; 80: 377-384 IF: 0.300

699. *Gotthardt A, Bury D, Kling HW, Otter R, Weiß T, Brüning T, Koch HM.
Quantitative investigation of the urinary excretion of three specific monoester metabolites of the plasticizer diisononyl adipate (DINA).
Excli J 2021; 20: 412-425 IF: 4.600 DOI: 10.17179/excli2021-3360

698. *Gambichler T, Hartenstein I, Dreissigacker M, Stockfleth E, Schaller J, Schulze HJ, Becker JC, Käfferlein HU, Brüning T, Lang K.
Expression of hedgehog signaling molecules in microcystic adnexal carcinoma.
Clin Exp Dermatol 2021; 70: 1635-1647 IF: 4.100 DOI: 10.1111/ced.14634

697. *Casjens S, JohnenG, Raiko I, Pesch B, Taeger D, Töpfer C, Schonefeld S, Moebus S, Jöckel KH, Brüning T, Weber DG.
Re-evaluation of potential predictors of calretinin and mesothelin in a population-based cohort study using assays for the routine application in clinical medicine.
BMJ Open 2021; 11: e039079 IF: 2.900 DOI: 10.1136/bmjopen-2020-039079

696. Brüning T, Bünger J, Casjens S, Raulf M.
Arbeitsmedizinische Forschung und Beratung in Pandemiezeiten.
DGUV Forum 2021; 3 Zum Beitrag

695. Behrens T, Brüning T. Wirksamkeit von Gesichtsmasken bei der Verhinderung von Atemwegsinfektionen. DGUV Forum 2021; 3 Zum Beitrag

694. *Sucker K, Zschiesche W, Aziz M, Drews T, Hummel T, Raulf M, Weiß T, Bury D, Werner S, Friedrich C, Bünger J, Pallapies D, Brüning T. Naphthalene: irritative and inflammatory effects on the airways.
Int Arch Occup Environ Health 2021; 94: 889-899 IF: 3.000 DOI: 10.1007/s00420-020-01636-0

693. *Tschersich C, Murawski A, Schwedler G, Rucic E, Moos RK, Kasper-Sonnenberg M, Koch HM, Brüning T, Kolossa-Gehring M.
Bisphenol A and six other environmental phenols in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017.
Sci Total Environ 2021; 763: 144615 IF:9.800 DOI: 10.1016/j.scitotenv.2020.144615

2020

692. *Lotz A, Pesch B, Casjens S, Lehnert M, Zschiesche W, Taeger D, Yeh CL, Weiß T, Schmidt-Wilcke T, Quetscher C, Gabriel S, Zella MAS, Woitalla D, Dydak U, van Thriel C, Brüning T.
Association of exposure to manganese and fine motor skills in welders - results from the WELDOX II study.
Neurotox 2020; 82: 137-145 IF: 3.400 DOI: 10.1016/j.neuro.2020.12.003

691. *Casjens S, Taeger D, Brüning T.
Author's reply to: cancer risks of firefighters: a systematic review and meta‑analysis of secular trends and region‑specific differences.
Int Arch Occup Environ Health 2021; 94: 355-356 IF: 3.000 DOI: 10.1007/s00420-020-01625-3

690. *Murawski A, Tschersich C, Rucic E, Scwedler G, Moos RK, Kasper-Sonnenberg M, Brüning T, Koch HM, Kolossa-Gehring M.
Parabens in urine of children and adolescents in Germany - human biomonitoring results of the german environmental survey 2014-2017 (GerES V)
Environ Res 2021; 194: 110502 IF: 8.300 DOI: 10.1016/j.envres.2020.110502

689. *Dorling L, Carvalho S, ...., Brauch H, Bremer M, Briceno I, Brüning T,..., Teo SH, Devilee P, Easton DF.
Breast cancer risk genes - association analysis in more than 113,000 women.
N Engl J Med 2021; 384: 428-439 IF:158.500 DOI: 10.1056/NEJMoa1913948

688. *Heba S, Sczesny-Kaiser M, Sucker K, Bünger J, Brüning T, Tegenthoff M, Schmidt-Wilcke T.
Pain perception, brain connectivity, and neurochemistry in healthy, Capsaicin-sensitive subjects.
Neural Plasticity 2020; 9125913 IF:3.100 DOI: 10.1155/2020/9125913

687. *Bartkowiak K, Casjens S, Anderas A, Ackar L, Joosse SA, Raiko I, Brüning T, Geffken M, Peine S, Johnen G, Weber DG, Pantel K.
Sensitive Blood-Based Detection of Asbestos-Associated Diseases Using Cysteine-Rich Angiogenic Inducer 61 as Circulating Protein Biomarker.
Clin Chem 2021; 67: 363-373 IF: 9.300 DOI: 10.1093/clinchem/hvaa232

686. *Apel P, Kortenkamp A, Koch HM, Vogel N, Rüther M, Kasper-Sonnenberg M, Conrad A, Brüning T, Kolossa-Gehring M
Time course of phthalate cumulative risks to male developmental health over a 27-year period: Biomonitoring samples of the German Environmental Specimen Bank.
Environ Int 2020; 137: 105467 IF:11.800 DOI: 10.1016/j.envint.2020.105467

685. *Guha N, Bouaoun L, Kromhout H, Vermeulen R, Brüning T, Behrens T, Peters S, Luzon V, Siemiatycki J, Xu M, Kendzia B, Guenel P, ..., Straif K, Olsson A.
Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium. Occup Environ Med 2021; 78: 269-274 IF: 4.900 DOI: 0.1136/oemed-2020-106770

684. *Schmied-Tobies MIH, Murawski A, Rucic E, Schwedler G, Bury D, Kasper-Sonnenberg M, Koslitz S, Koch HM, Brüning T, Kolossa-Gehring M. Alkyl pyrrolidone solvents N-methyl-2-pyrrolidone (NMP) and N-ethyl-2-pyrrolidone (NEP) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerESV). Environ Int 2020; 146: 106221 IF:11.800 DOI:10.1016/j.envint.2020.106221

683. *Monsé C, Vossen K, Martiny A, Kirchner M, Dragan G, Jettkant B, Bünger J, Brüning T, Emmel C. Stickoxidvergleichsmessungen im IPA-Expositionslabor. Gefahrstoffe - Reinhaltung der Luft 2020; 80: 377-384 IF:0.300

682. *Ecke T, Kiani A, Schlomm T, Friedersdorff F, Rabien A, Jung K, Kilic E, Boström P, Tervahartiala M, Taimen P, Gleichenhagen J, Johnen G, Brüning T, Koch S, Roggisch J, Wirtz R. Prognostic Role of Survivin and Macrophage Infiltration Quantified on Protein and mRNA Level in Molecular Subtypes Determined by RT-qPCR of KRT5, KRT20, and ERBB2 in Muscle-Invasive Bladder Cancer Treated by Adjuvant Chemotherapy.
Int J Mol Sci 2020; 21: E7420 IF: 5.600 DOI: 10.3390/ijms21197420

681. *Monsé C, Raulf M, Jettkant B, van Kampen V, Kendzia B, Schürmeyer L, Seifert CE, Marek EM, Westphal G, Rosenkranz N, Merget R, Brüning T, Bünger J.
Health effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers.
Arch Tox 2021; 95: 53-65 IF:6.100 DOI: 10.1007/s00204-020-02923-y

680. *Knobloch J, Casjens S, Lehnert M, Yanik S, Körber S, Lotz A, Rupp J, Raulf M, Zschiesche W, Weiß T, Kronsbein J, Koch A, Brüning T, Pesch B,
Exposure to welding fumes suppresses the activity of T-helper cells.
Environ Res 2020; 189: 109913 IF: 8.300 DOI: 10.1016/j.envres.2020.109913

679. *Connolly A, Koslitz S, Bury D, Brüning T, Conrad A, Kolossa-Gehring M, Coggins MA, Koch HM.
Sensitive and selective quantification of glyphosate and aminomethylphosphonic acid (AMPA) in urine of the general population by gas chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci 2020; 1158: 122348 IF: 1.911 DOI: 10.1016/j.jchromb.2020.122348

678. *Brik A, Weber DG, Casjens S, Rozynel P, Meier S, Behrens T, Stamatis G, Darwiche K, Theegarten D, Brüning T, Johnen G.
Digital PCR for the analysis of MYC copy number variation in lung cancer.
Disease Markers 2020; 1-8 IF: 3.464 DOI: 10.1155/2020/4176376

677. *Bauer A, Haufe E, Heinrich L, Seidler A, Schulze HJ, Elsner P, Drexler H, Letzel S, John SM, Fartasch M, Brüning T, Dugas-Breit S, Gina M, Weistenhöfer W, Bachmann K, Bruhn I, Lang BM, Brans R, Allam JP, Grobe W, Westerhausen S, Knuschke P, Wittlich M, Diepgen TL, Schmitt J; FB181 study group.
Basal cell carcinoma risk and solar UV exposure in occupationally relevant anatomic sites: do histological subtype, tumor localization and Fitzpatrick phototype play a role? A population-based case-control study.
J Occup Med Toxicol 2020 eCollection IF: 3.000 DOI: 10.1186/s12995-020-00279-8

676. *van Kampen V, Hoffmeyer F, Seifert C, Brüning T, Bünger J.
Occupational health hazards of street cleaners - a literature review considering prevention practices at the workplace.
Int J Occup Med Environ Health. 2020 33: 701-732 IF: 2.000 DOI: 10.13075/ijomeh.1896.01576

675. *Liebers V, Brüning T, Raulf M. Occupational endotoxin exposure and health effects.
Arch Toxicol 2020; 94: 3629-3644 IF: 6.100 DOI: 10.1007/s00204-020-02905-0

674. *Schwedler G, Rucic E, Koch HM, Lessmann F, Brüning T, Conrad A, Schmied-Tobies MIH, Kolossa-Gehring M. Metabolites of the substitute plasticiser Di-(2-ethylhexyl) terephthalate (DEHTP) in urine of children and adolescents investigated in the German Environmental Survey GerES V, 2014-2017. Int J Hyg Environ Health 2020; 230: 113589 IF: 6.000 DOI: 10.1016/j.ijheh.2020.113589

673. *Monsé C, Hagemeyer O, van Kampen V, Raulf M, Weiß T, Menne E, Jettkant B, Kendzia B, Merget R, Brüning T, Bünger J. Human inhalation study with Zinc Oxide: Analysis of zinc levels and biomarkers in exhaled breath condensate. Adv Exp Med Biol 2021; 95: 53-65 IF: 3.650 DOI:10.1007/5584_2020_572

672. Gambichler T, Wrobel M, Koim S, Becker J, Käfferlein HU, Büning T, Lang K. A study on DNA hydroxymethylation in Kaposi sarcoma and cutaneous angiosarcoma. J Eur Acad Dermatol & Venereol 2020; IF: 9.200DOI: 10.1111/jdv.16444

671. Weiß T, Koslitz S, Bünger J, Brüning T. Human-Biomonitoring nach „Fume and Smell Events“ in Verkehrsflugzeugen – Eine Übersichtsarbeit zum aktuellen Zwischenstand. Umweltmed - Hygiene - Arbeitsmed 2020; 25: 7-15

670. *Lehnert M, Weber DG; Taeger D, Raiko I, Kollmeier J, Stephan-Falkenau S, Brüning T, Johnen G.
Determinants of plasma calretinin in patients with malignant pleural mesothelioma.
BMC Res Notes 2020; 13: 359 IF: 1.800

669.*Köhler CU, Walter M, Lang K, Plöttner S, Roghmann F, Noldus J, Tannapfel A, Tam YC, Käfferlein HU, Brüning T.
In-vitro identification and invivo confirmation of DNA methylation biomarkers for urothelial cancer. Biomedicines 2020; 8: E233 IF: 4.700 DOI: 10.3390/biomedicines8080233

668. *Wichert K, Rabstein S, Stang A, Erbel R, Eisele L, Arendt M, Keimer A, Dragano N, Hoffmann W, Lerch MM, Roskoden FC, Schmidt CO, Völzke H, Jöckel KH, Brüning T, Behrens T. Associations between shift work and risk of colorectal cancer in two German cohort studies. Chronobiol Int. 2020; 37: 1235-1243 IF: 2.800 DOI: 10.1080/07420528.2020.1782930.

667. *Weiß T, Breuer D, Bury D, Friedrich C, Werner S, Aziz M, Hummel T, Raulf M, Zschiesche W, Sucker K, Pallapies D, Bünger J, Brüning T. (Mono-) Exposure to Naphthalene in the Abrasives Industry: Air Monitoring and Biological Monitoring. Ann Work Expo Health. 2020; 64: 982-992 IF: 2.600 DOI:10.1093/annweh/wxaa062

666. *Rabstein S, Behrens T, Pallapies D, Eisenhawer C, Brüning T. Schichtarbeit und Krebserkrankungen. Zbl Arbeitsmed 2020; 70; 249-255 DOI: 10.1007/s40664-020-00398-3

665. *Weber DG, Casjens S, Brik A, Raiko I, Lehnert M, Taeger D, Gleichenhagen J, Kollmeier J, Bauer TT, Brüning T, Johnen G. Circulating long non-coding RNA GAS5 (growth arrest-specific transcript 5) as a complement marker for the detection of malignant mesothelioma using liquid biopsie. Biomark Res. 2020. IF: 11.100 DOI: 10.1186/s40364-020-00194-4

664. *Zhang H, Thomas U, Leocarpentier J, Barnes D, ...Brauch H, Brenner H, Broeks A, Brucker S, Brüning T, ..., Easton D, Chatterjee N, Garcia-Closas M. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 2020; 52: 572-581 IF:30.800 DOI: 10.1038/s41588-020-0609-2

663. *Ringbeck B, Bury D, Hayen H, Weiß T, Brüning T, Koch HM. Determination of di-n-butyl adipate (DnBA) metabolites as possible biomarkers of exposure in human urine by online-SPE-LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2020; 1141: 122029 IF: 1.911 DOI: 10.1016/j.jchromb.2020.122029

662.* Lehnert M, Beine A, Hoffmeyer F, Taeger D, Brüning T, Raulf M. Self-reported Survey on Allergy Symptoms Among First-Year Students in Veterinary Medicine: A Preamble to the AllergoVet Cohort Study. Adv Exp Med Biol. 2020; 1279: 9-14 IF: 3.650 DOI: 10.1007/5584_2020_502

661. *Kleinbeck S, Schäper M, Pacharra M, Lehmann ML, Golka K, Blaszkewicz M, Brüning T, van Thriel C. A short-term inhalation study to assess the reversibility of sensory irritation in human volunteers. Arch Toxicol 2020; 94: 1687-1701 IF: 6.100 DOI: 10.1007/s00204-020-02703-8

660. * Kapoor PM, Mavaddat N, Choudhury PP, ...; Brauch H, Brenner H, Brüning T

.;....Kraft P, Easton DF, Milne RL, García-Closas M, Chang-Claude, J. Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. J Natl Cancer Inst 2021; 113: 329-337 IF: 13.757 DOI: 10.1007/s00204-020-02703-8

659. *van Kampen V, Hoffmeyer F, Monsé C, Raulf M, Brüning T, Bünger J, Sucker K. Discrimination between atopic, allergic, and asthmatic volunteers for human exposure studies on sensory irritation. Adv Exp Med Biol 2020; 1279; 27-35 IF: 3.650 DOI: 10.1007/5584_2020_520

658. *Hoffmeyer F, Beine A, Lehnert M, Berresheim H, Taeger D, van Kampen V, Sander I, Zahradnik E, Brüning T, Raulf M. The pattern of sensitization influences exhaled and nasal nitric oxide levels in young adults Adv Exp Med Biol 2020; 1279: 15-26 IF: 3.650DOI: 10.1007/5584_2020_509

657. *Ge C, Peters S, Olsson A, Portengen L, Schüz J, Almansa J, Behrens T, Pesch B, Kendzia B, Ahrens W, Bencko V, Benhamou S, Boffetta P, Bueno-de-Mesquita B, Caporaso N, Consonni D, Demers P, Fabiánová E, Fernández-Tardón G, Field J, Forastiere F, Foretova L, Guénel P, Gustavsson P, Ho V, Janout V, Jöckel K-H, Karrasch S, Landi MT, Lissowska J, Luce D, Mates D, McLaughlin J, Merletti F, Mirabelli D, Plato N, Pohlabeln H, Richiardi L, Rudnai P, Siemiatycki J, Świątkowska B, Tardón A, Wichmann HE, Zaridze D, Brüning T , Straif K, Kromhout H, Vermeulen R. Respirable Crystalline Silica Exposure, Smoking, and Lung Cancer Subtype Risks: A Pooled Analysis of Case-control Studies. Am J Respir Crit Care Med 2020 IF: 24.700DOI: 10.1164/RCCM.201910-1926OC

656. *Gambichler T, Wrobel M, Koim S, Becker JC, Käfferlein HU, Brüning T, Lang K. A study on DNA hydroxymethylation in Kaposi sarcoma and cutaneous angiosarcoma. J Eur Acad Dermatol & Venereol 2020; 34: e785-e787 IF: 9.200DOI: 10.1111/JDV.1644

655. *Gambichler T, Koim S, Wrobel M, Käfferlein HU, Brüning T, Stockfleth E, Becker JC, Lang K. Expression of programmed cell death proteins in Kaposi sarcoma and cutaneous angiosarcoma. J Immunother 2020; 43: 169-174 IF: 3.900

DOI: 10.1111/jdv.16271654. *Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, …, Brauch H, Brenner H, Briceno I, Broeks A, Brüning T , …, …, Chenevix-Trench G, Zheng W, Kraft P, Jiang X. Transcriptome-wide association study of breast cancer risk by estrogen-receptor status. Genet. Epidemiol 2020; 44; 442-468 IF: 2.100 DOI: 10.1002/GEPI.22288

653. *Casjens S, Brüning T, Taeger D. Cancer risks of firefighters: a systematic review and meta-analysis of secular trends and region-specific differences. Int Arch Occup Environ Health 2020; 93: 839-852 IF: 3.000 DOI: 10.1007/S00420-020-01539-0

652. *Casjens S, Brüning T, Taeger D. Cancer incidence and mortality in firefighters. Asian Pac. J. Cancer Prev. 2020; 21: 575 IF: 2.514 DOI: 10.31557/APJCP.2020.21.3.575

651. *Benderska-Söder N, Hovanec J, Pesch B, Goebell PJ, Roghmann F, Noldus J, Rabinovich J, Wichert K, Gleichenhagen J, Käfferlein HU, Köhler CU, Johnen G, Kernig K, Hakenberg O, Jahn D, Todenhöfer T, Stenzl A, Gleissner J, Gerwert K, El-Mashtoly SF, Behrens T, Brüning T, Schmitz-Dräger BJ. Toward noninvasive follow-up of low-risk bladder cancer - Rationale and concept of the UroFollow trial. Urol Oncol 2020; 38: 886-895 IF: 0.818 DOI: 10.1016/J.UROLONC.2020.01.006

650. *Aweimer A, Jettkant B, Monsé C, Hagemeyer O, van Kampen V, Kendzia B, Gering V, Marek EM, Bünger J, Mügge A, Brüning T, Merget R. Heart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults. J Occup Med Toxicol 2020; 15: 4 IF: 3.000 DOI: 10.1186/S12995-020-00255-2

649. *Fachal L, Aschard H, Beesley J, ..., Brauch H, Brenner H, Briceno I, Brock IW, Brooks-Wilson A, Brüning T, ....Chevenix-Trench G, Simard J, Easton DF, Kraft P, Düning AM. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nat Genet 2020; 49: 1767 IF: 30.800

648. *Schwedler G, Rucic E, Lange R, Conrad A, Koch HM, Pälmke C, Brüning T,, Schulz C, Schmied-Tobies MI, Daniels A, Kolossa-Gehring M. Phthalate metabolites in urine of children and adolescents in Germany. Human biomonitoring results of the German Environmental Survey GerES V, 2014-2017. Int J Hyg Environ Health 2020; 225: 113444 IF: 6.000

647. *Rosenkranz D, Bünger J, Hoffmeyer F, Monsé C, van Kampen V, Raulf M, Brüning T, Sucker K. How healthy is healthy? Comparison between self-reported symptoms and clinical outcomes in connection with the enrollment of volunteers for human exposure studies on sensory irritation effects. Adv Exp Med Biol 2020; 1271: 49-59 IF: 3.650

646. *Nehring A, Bury D, Ringbeck B, Kling HW, Otter R, Weiß T, Brüning T, Koch HM. Metabolism and urinary excretion kinetics of di(2-ethylhexyl) adipate (DEHA) in four human volunteers after a single oral dose. Toxicol Letters 2020; 321: 95-192 IF: 3.500

645. *Liebers V, Kendzia B, Monsé C, Jettkant B, Stubel H, Borowitzki G, Hagemeyer O, Brüning T, Merget R, Raulf M. Whole blood assay as a tool to describe the effects of Zinc Oxide exposure on innate immunity. Adv Biol Med 2020; 1271: 69-81 IF: 2.126

644. *Apel P, Kortenkamp A, Koch HM, Vogel N, Rüther M, Kasper-Sonnenberg M, Conrad A,

Brüning T , Kolossa-Gehring M. Time course of phthalate cumulative risks to male developmental health over a 27-year period: Biomonitoring samples of the German Environmental Specimen Bank. Environ Int 2020; 137: 105467 IF: 11.800

643. *Monsé C, Raulf M, Hagemeyer O, van Kampne V, Kendzia B, Gering V, Marek E, Jettkant B, Bünger J, Merget R, Brüning TAirway inlfammation after inhalation of nano-sized particles in human volunteers. BMC Pulm Med 2019; 19: 266 IF: 3.100

642. *Wahrendorf M, Marr A, Antoni M, Pesch B, Jöckel KH, Lunau T, Moebus S, Arendt M, Brüning T, Behrens T, Dragano N. Agreement of self-reported and administrative data on employment histories in a german cohort study: A sequence analysis. Eur J Popul 2019; 35: 329-346 IF: 1.280

641. *Ulrich N, Bury D, Koch HM, Rüther M, Weber T, Käfferlein H-U, Weiß T, Brüning T, Kolossa-Gehring M. Correction to: Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014. Int Arch Occup Environ Health 2020; 93: 147 DOI: 10.1007/S00420-019-01506-4 IF: 3.000

640. *Lessmann F, Kolossa-Gehring M, Apel P, Rüther M, Pälmke C, Harth V, Brüning T, Koch HM. German Environmental Specimen Bank: 24-hour urine samples from 1999 to 2017 reveal rapid increase in exposure to the para-phthalate plasticizer di(2-ethylhexyl) terephthalate (DEHTP). Environ Int 2019; 132: 105102 IF 11.800

639. *Figlioli G, Bogliolo M, Catucci I, Caleca L, …, Brauch, Hiltrud, Brenner H, Brüning T, Burwinkel B, …, Parsons MT, Pharoah PD, Fostira F, Toland AE, Andrulis IL, Ramus SJ, werdlow AJ, Greene MH, Chung WK, Milne RL, Chenevix-Trench G, Dörk T, Schmidt MK, Easton DF, Radice P, Hahnen E, Antoniou AC, Couch FJ, Nevanlinna H, Surrallés J, Peterlongo P. The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. NPJ Breast Cancer 2019; 5: 38 IF: 5.900

638. *Sucker K, Hoffmeyer F, Monsé C, Jettkant B, Berresheim H, Rosenkranz N, Raulf M, Bünger J, Brüning T. Ethyl acrylate: influence of sex or atopy on perceptual ratings and eye blink frequency. Arch Toxicol 2019; 93: 2913-2926 IF 6.100

637. Zahradnik E, Thullner I, Liebers V, Sander I, Walther C, Schäl N, Brüning T, Raulf M. Exposition gegenüber Allergenen, Endotoxinen und 1-3beta-Glucan in verschiedenen Bereichen der veterinärmedizinischen Fakultät. Gefahrstoffe - Reinhaltung der Luft 2019; 79; 323-334 IF 0.300

636. *Pesch B, Kendzia B, Pohlabeln H, Ahrens W, Wichmann HE, Siemiatycki J, Taeger D, Zschiesche W, Behrens T, Jöckel KH, Brüning T.Exposure to welding fumes, hexavalent chromium, or nickel and lung cancer risk. Am J Epidemiol 2019; 188: 1984-1993 IF 3.500

635. *Monsé C, Jettkant B, Schramm B, Broding H, Knappe M, Michl M, Hoffmeyer F, Sucker K, Brüning T, Bünger J. Effects of Exposure to Carbon Dioxide in Potash Miners. Adv Exp Med Biol 2019; 1150: 1-10 IF 3.650

634. Lang K, Kahveci S, Bonberg N, Wichert K, Behrens T, Hovanec J, Roghmann F, Noldus J, Tam YC, Tannapfel A, Käfferlein HU, Brüning T. TGFBI protein is increased in the urine of patients with high-grade urothelial carcinomas, and promotes cell proliferation and migration. IJMS 2019; 20: 4483 IF 5.600

633. Liebers V, Düser M, Kendzia B, Brüning T, Raulf M. Quantifizierung von Endotoxin mit dem rekombinanten Faktor-C-(rFC)-Test - Vergleich mit dem LAL-Test. Gefahrstoffe Reinhaltung Luft 2019; 79: 337-341 IF 0.300

632. *Behrens T, Burek K, Pallapies D, Kösters L, Lehnert M, Beine A, Wichert K, Kantermann T, Vetter C, Brüning T, Rabstein S. Decreased psychomotor vigilance of female shift workers after working night shifts. PLoS ONE 2019; 14: e0219087 IF 3.700

631. *Hoffmeyer F, Sucker K, Berresheim H, Monsé C, Jettkant B, Beine A, Raulf M, Brüning T, Bünger J. Methodological implications and repeatability of nasal nitric oxide: Relevance for challenge studies. Adv Exp Med Biol. 2019; 113: 1-10 IF 3.650

630. *Kasper-Sonnenberg M, Koch HM, Apel P, Rüther M, Pälmke C, Brüning T, Kolossa-Gehring M. Time trend of exposure to the phthalate plasticizer substitute DINCH in Germany from 1999 to 2017: Biomonitoring data on young adults from the Environmental Specimen Bank (ESB). Int J Hyg Environ Health. 2019; 222: 1084-1092 IF 6.000

629. *van Kampen V, Brüning T, Merget R. Serial fractional exhaled nitric oxide measurements off and at work in the diagnosis of occupational asthma. Am J Ind Med 2019; 62: 663-671IF: 3.500

628. *Nehring A, Bury D, Kling HW, Weiß T, Brüning T, Koch HM. Determination of human urinary metabolites of the plasticizer di(2-ethylhexyl) adipate (DEHA) by online-SPE-HPLC-MS/MS. J Chromatogr B Analyt technol Biomed Life Sci 2019; 1124: 239-246 IF: 1.911

627. *Monsé C, Monz C, Stahlmecke B, Jettkant B, Bünger J, Brüning T, Neumann V, Dahmann D. Development and validation of a novel particle source for nano-sized test aerosols. Aerosol Air Qual Res 2019; 677-687 IF: 4.000

626. *Lehnert M, Behrens T, Tulowietzki J, Guldner K, Brüning T, Taeger D. Cancer in glass workers: a systematic review and meta-analysis. Int Arch Occup Environ Health 2020; 93: 1-10 IF 3.000

625. *Klotz K, Weiß T, Zobel M, Bury D, Breuer D, Werner S, Sucker K, Zschiesche W, Göen T,Brüning T, Drexler H. Validity of different biomonitoring parameters in human urine for the assessment of occupational exposure to naphthalene. Arch Toxicol 2019; 93: 2185-2195 IF: 6.100

624. *Jiménez-Ramírez C, Casjens S, Juárez-Pérez CA, Raiko I, Del Razo LM, Taeger D, Calderón-Aranda ES, Rihs HP, Acosta-Saavedra LC, Weber DG, Cabello-López A, Pesch B, Ochoa-Vázquez MD, Burek K, Torre-Bouscoulet L, Pérez-Padilla JR, García-Bazan EM, Brüning T, Johnen G, Aguilar-Madrid G. Mesothelin, Calretinin, and Megakaryocyte Potentiating Factor as biomarkers of malignant pleural mMesothelioma. Lung 2019; 197: 641-649 IF 5.000

623 *Ditchen D, Ellegast R, Pflaumbaum W, Bünger J, Fartasch M, Hagemeyer O, Brüning T, Zagrodnik F. Von der Diagnose zum Berufskrankheiten-Verdacht - BK-Info der Deutschen Gesetzlichen Unfallversicherung e. V. (DGUV). Zbl Arbeitsmed 2019; 69: 245-260

622. *Engel J, van Kampen V, Gering V, Hagemeyer O, Brüning T, Raulf M, Merget R. Non-invasive tools beyond lung function before and after specific inhalation challenges for diagnosing occupational asthma. Int Arch Occup Environ Health 2019; 92: 1067-1076 IF 3.000

621. *Casjens S, Brüning T, Taeger D. Meta-Analysis of cancer risks of professional firefighters. Int J Cancer 2019. 145: 1701 IF: 6.400

620. *Bury D, Griem P, Wildemann T, Brüning T, Koch HM. Urinary metabolites of the UV filter 2-Ethylhexyl salicylate as biomarkers of exposure in humans. Toxicol Lett. 2019; 309: 35-41 IF: 3.500

619. *Gambichler T, Salveridou K, Schmitz L, Käfferlein HU, Brüning T, Stockfleth E, Sand M, Lang K. Low Drosha protein expression in cutaneous T cell lymphoma is associated with worse disease outcome. J Eur Acad Dermatol Venereol 2019; 33: 1695-1699 IF: 9.200

618. *Westphal GA, Rosenkranz N, Brik A, Weber DG, Föhring I, Monsé C, Kaieser N, Hellack B, Mattenklott M, Brüning T, Johnen G, Bünger J. Multi-walled carbon nanotubes induce stronger migration of inflammatory cells in vitro than asbestos or granular particles but a similar pattern of inflammatory mediators. Toxicol in Vitro 2019; 58: 215-223 IF: 3.200

617. *Köhler CU, Bonberg N, Ahrens M, Behrens T, Hovanec J, Eisenacher M, Noldus J, Deix T, Braun K, Gohlke H, Walter M, Tannapfel A, Tam YC, Sommerer F, Marcus K, Jöckel KH, Erbel R, Cantor CR, Käfferlein HU, Brüning T. Non-invasive diagnosis of urothelial cancer in urine using DNA hypermethylation signatures - Gender matters. Int J Cancer 2019; 145: 2861-2872 IF: 6.400

616. *Müller A, Hovanec J, Josephs B, Wiethege T, Brüning T, Behrens T. A Two-Level Biobank Data Protection Concept for Project-Driven Human Sample Collections. Biopreserv Biobank 2019; 17: IF: 1.600

615. *Hovanec J, Weiß T, Koch H, Pesch B, Behrens T, Kendzia B, Arendt M, Dragano N, Moebus S, Schmidt B, Brüning T, Jöckel KH. Smoking and urinary cotinine by socioeconomic status in the Heinz Nixdorf Recall Study. J Epidemiol Community Health. 2019; 73: 489-495 IF: 6.300

614. *Bury D, Brüning T , Koch HM. Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2019; 1110-1111:59-66 IF: 1.911

613. *Witzke KE, Großerueschkamp F, Jütte H, Horn M, Roghmann F, von Landenberg N, Bracht T, Kallenbach-Thieltges A, Käfferlein H, Brüning T, Schork K, Eisenacher M, Marcus K, Noldus J, Tannapfel A, Sitek B, Gerwert K. Integrated Fourier Transform Infrared Imaging and Proteomics for Identification of a Candidate Histochemical Biomarker in Bladder Cancer. Am J Pathol 2019; 189: 619-631 IF: 6.000

612. *Rabstein S, Burek K, Lehnert M, Beine A, Vetter C, Harth V, Putzke S, Kantermann T, Walther J, Wang-Sattler R, Pallapies D, Brüning T, Behrens T. Differences in twenty-four-hour profiles of blue-light exposure between day and night shifts in female medical staff. Sci Total Environ 2019; 653:1025-1033 IF: 9.800

611. *Weber DG, Brik A, Casjens S, Burek K, Lehnert M, Pesch B, Taeger D, Brüning T

, Johnen G; MoMar study group. Are circulating microRNAs suitable for the early detection of malignant mesothelioma? Results from a nested case-control study. BMC Res Notes 2019;12:77 IF: 1.800

610. *Bury D, Modick-Biermann H, Leibold E, Brüning T , Koch HM. Urinary metabolites of the UV filter octocrylene in humans as biomarkers of exposure. Arch Toxicol. 2019; 93: IF: 6.100

609. *Bury D, Saillenfait AM, Marquet F, Käfferlein HU, Brüning T, Koch HM. Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration. Arch Toxicol. 2019; 93: 921-929 IF: 6.100

608. *Pesch B, Casjens S, Woitalla D, Dharmadhikari S, Edmondson DA, Zella MAS, Lehnert M, Lotz A, Herrmann L, Muhlack S, Kraus P, Yeh CL, Glaubitz B, Schmidt-Wilcke T, Gold R, van Thriel C, Brüning T, Tönges L, Dydak U. Impairment of Motor Function Correlates with Neurometabolite and Brain Iron Alterations in Parkinson's Disease. Cells. 2019; 29: 8 IF: 6.000

607. *Mavaddat N; Michailidou K, Dennis J; ...Brentnall A; Brock IW, Brooks-Wilson A, Brucker SY, Brüning TBurwinkel B; ... Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. Am J Hum Genet. 2019;104: 21-34 IF: 9.800

606. *Kendzia B, Koppisch D, Van Gelder R, Gabriel S, Zschiesche W, Behrens T, Brüning T, Pesch B. Modelling of exposure to respirable and inhalable welding fumes at German workplaces. J Occup Environ Hyg. 2019 16: 400-409 IF: 3.000

605. Fartasch M, Zschiesche W, Brüning T. Heller Hautkrebs als BK-Folge: Berücksichtigung von dermatologischen Zweittumoren. Dermatologie in Beruf und Umwelt. 2018; 66 : 151

604. *Rosenberger A, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Haiman CA, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Kiemeney B, Lazarus P, Haugen A, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Brunnsstöm H, Goodman GE, Doherty JA, Chen C, Teare MD, Wichmann HE, Manz J, Risch A, Muley TR, Johansson M, Brennan P, Landi MT, Amos CI, Pesch B, Johnen G, Brüning T, Bickeböller H, Gomolka M. Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners. Int Arch Occup Environ Health. 2018; 91 : 937 - 950 IF: 3.000

603. Behrens T, Lehnert M, Zschiesche W, Taeger D, Pallapies D, Brüning T. Ableitung des Arbeitsplatzgrenzwertes für Mangan (MnA) bei Schweißarbeiten. Arbeitsmed Sozialmed Umweltmed 2018; 53: 598-601

602. Behrens T, Pesch B, Brüning T. Herausforderungen bei der Bewertung synergistischer Effekte aus bevölkerungsbezogenen Studien. ASU 2018; 53: 526-529

601. Behrens T, Taeger D, Pallapies D, Brüning T. Synergistische Effekte nach Mehrfachexposition – Bewertung für die Regulation. ASU 2018; 53: 452-458

600. Weiß T, Hagmann M, Hebisch R, Wolf T, Brüning T. TRGS 910 führt zum Präventionserfolg auch in kleinen Betrieben. DGUV Forum 2018; 8: 34-35

599. *Koch HM, Lessmann F, Swan SH, Hauser R, Kolossa-Gehring M, Frederiksen H, Andersson AM, Thomsen C, Sakhi AK, Bornehag CG, Mueller JF, Rudel RA, Braun JM, Harth V, Brüning T. Analyzing terephthalate metabolites in human urine as biomarkers of exposure: Importance of selection of metabolites and deconjugation enzyme. J Chromatogr B Analyt Technol Biomed Life Sci 2018; 1100-1101: 91-92 IF: 1.911

598. *Rieger MA, Liebers V, Nübling M, Brüning T, Brendel B, Hoffmeyer F, Raulf M. Adaptation to Occupational Exposure to Moderate Endotoxin Concentrations: A Study in Sewage Treatment Plants in Germany. Adv Exp Med Biol. 2018; 89-109 IF: 3.650

597. *Shu X, Wu L, Khankari NK, Shu XO, Wang TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W; Breast Cancer Association Consortium. Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis. Int J Epidemiol. 2018; 11: 55-64 IF: 7.700

596. *Johnen G, Burek K, Raiko I, Wichert K, Pesch B, Weber DG, Lehnert M, Casjens S, Hagemeyer O, Taeger D, Brüning T; MoMar Study Group. Prediagnostic detection of mesothelioma by circulating calretinin and mesothelin - a case-control comparison nested into a prospective cohort of asbestos-exposed workers. Sci Rep 2018; 8: 14321. IF: 4.600

595. *Monsé C, Jettkant B, Schramm BKH, Broding HC, Knappe M, Michl M, Hoffmeyer F, Sucker K, Brüning T , Bünger J. Effects of Exposure to Carbon Dioxide in Potash Miners. Adv Exp Med Biol. 2019; 1150: 1-10 IF: 3.650

594. *Bermejo JL, Huang G, Manoochehri M, Mesa KG, Schick M, Silos RG, Ko YD, Brüning T, Brauch H, Lo WY, Hoheisel JD, Hamann U. Long intergenic noncoding RNA 299 methylation in peripheral blood is a biomarker for triple-negative breast cancer. Epigenomics 2019; 11: 81 - 83 IF: 3.800

593. *Hertel J, Rotter M, Frenzel S, Zacharias HU, Krumsiek J, Rathkolb B, Hrabe de Angelis M, Rabstein S, Pallapies D, Brüning T, Grabe HJ, Wang-Sattler R. Dilution correction for dynamically influenced urinary analyte data. Anal Chim Acta 2018; 1032:18-31 IF: 6.200

592. *Rotter M, Brandmaier S, Covic M, Burek K, Hertel J, Troll M, Bader E, Adam J, Prehn C, Rathkolb B, Hrabe de Angelis M, Grabe HJ, Daniel H, Kantermann T, Harth V, Illig T, Pallapies D, Behrens T, Brüning T, Adamski J, Lickert H, Rabstein S, Wang-Sattler R. Night Shift Work Affects Urine Metabolite Profiles of Nurses with Early Chronotype. Metabolites. 2018; 8. pii: E45. IF: 4.100

591. *Casjens S, Pesch B, van Thriel C, Zschiesche W, Behrens T, Weiss T, Pallapies D, Arendt M, Dragano N, Moebus S, Jöckel KH, Brüning T. Associations between blood lead, olfaction and fine-motor skills in elderly men: Results from the Heinz Nixdorf Recall Study. Neurotoxicology. 2018; 68: 66 - 72. IF: 3.400

590. *Aguilar-Madrid G, Pesch B, Calderón-Aranda ES, Burek K, Jiménez-Ramírez C, Juárez-Pérez CA, Ochoa-Vázquez MD, Torre-Bouscoulet L, Acosta-Saavedra LC, Sada-Ovalle I, García-Figueroa J, Alvarado-Cabrero I, Castillo-González P, Báez-Saldaña AR, Pérez-Padilla JR, Osnaya-Juárez J, Rivera-Rosales RM, García-Bazán EM, Bautista-Aragón YL, Lazcano-Hernandez E, Munguía-Canales DA, Argote-Greene LM, Taeger D, Weber DG, Casjens S, Raiko I, Brüning T, Johnen G. Biomarkers for Predicting Malignant Pleural Mesothelioma in a Mexican Population. Int J Med Sci 2018;15: 883-891. IF: 3.600

589. *Liebers V, Kendzia B, Stubel H, Borowitzki G, Gering V, Monsé C, Hagemeyer O, Merget R, Brüning T, Raulf M. Cell Activation and Cytokine Release Ex Vivo: Estimation of Reproducibility of the Whole-Blood Assay with Fresh Human Blood. Adv Exp Med Biol. 2018; 1108: 25-36 IF: 3.650

588. *Engel J, van Kampen V, Lotz A, Abramowski J, Gering V, Hagemeyer O, Brüning T

, Raulf M, Merget R. An increase of fractional exhaled nitric oxide after specific inhalation challenge is highly predictive of occupational asthma. Int Arch Occup Environ Health. 2018; 91: 799 - 809 IF: 3.000

587. *Walter RFH, Rozynek P, Casjens S, Werner R, Mairinger FD, Speel EJM, Zur Hausen A, Meier S, Wohlschlaeger J, Theegarten D, Behrens T, Schmid KW, Brüning T, Johnen G.Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer. PLoS One. 2018; 13: e0195716 IF: 3.700

586. Zahradnik E, Sander I, van Kampen V, Brüning T, Raulf M. Entwicklung eines Immunoassays zur Quantifizierung von Saccharopolyspora- Antigenen. Atemwegs- und Lungenkrankheiten 2018; 44: 144

585. *van Kampen V, Sander I, Merget R, Brüning T, Raulf M. Baker's Asthma: Is the ratio of rye flour-specific IgE to total IgE more suitable to predict the outcome of challenge test than specific IgE alone. Adv Exp Med Biol. 2018; 1070: 1 - 7. IF: 3.650

584. *Lehnert M, Beine A, Burek K, Putzke S, Schlösser S, Pallapies D, Brüning T, Behrens T, Rabstein S. Vitamin D supply in shift working nurses. Chronobiol Int 2018; 25: 724-729 IF: 2.800

583. Fartasch M, Brüning T. Das Kontaktekzem. DGUV Forum 2018; 3: 15-16

582. Weiß T, Koch HM, Käfferlein HU, Brüning T. Die Aufnahme von Gefahrstoffen über Atemluft, Haut und Mund. DGUV Forum 2018; 3: 22-23

581. Reinert D, Jahn F, Brüning T, Herrmann J. Forschung zur Prävention und Berufskrankheiten durch die DGUV. DGUV Forum 2018; 3: 9-11

580. Raulf M, Brüning T. Berufliche Atemwegsallergien. DGUV Forum 2018; 3: 17-18579. Johnen G, Behrens T,Brüning T. Biomarker für die nachgehende Vorsorge. DGUV Forum 2018; 3: 19-21

578. *Hoffmeyer F, Sucker K, Berresheim H, Monsé C, Jettkant B, Beine A, Raulf M,

Brüning T, Bünger J. Methodological Implications and Repeatability of Nasal Nitric Oxide: Relevance for Challenge Studies. Adv Exp Med Biol 2018; 1111: 1-10 IF: 3.650

577. *Ulrich N, Bury D, Koch HM, Rüther M, Weber T, Käfferlein HU, Weiß T, Brüning T, Kolossa-Gehring M. Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014. Int Arch Occup Environ Health. 2018; 91: 1073 - 1082 IF: 3.000

576. *Cordina-Duverger E, Menegaux F, Popa A, Rabstein S, Harth V, Pesch B, Brüning T, Fritschi L, Glass DC, Heyworth JS, Erren TC, Castaño-Vinyals G, Papantoniou K, Espinosa A, Kogevinas M, Grundy A, Spinelli JJ, Aronson KJ, Guénel P. Night shift work and breast cancer: a pooled analysis of population-based case-control studies with complete work history. Eur J Epidemiol. 2018; 33: 369 - 379. IF: 13.600

575. *Hovanec J, Siemiatycki J, Conway DI, Olsson A, Stücker I, Guida F, Jöckel KH, Pohlabeln H, Ahrens W, Brüske I, Wichmann HE, Gustavsson P, Consonni D, Merletti F, Richiardi L, Simonato L, Fortes C, Parent ME, McLaughlin J, Demers P, Landi MT, Caporaso N, Tardón A, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, Lissowska J, Fabianova E, Field J, Dumitru RS, Bencko V, Foretova L, Janout V, Kromhout H, Vermeulen R, Boffetta P, Straif K, Schüz J, Kendzia B, Pesch B, Brüning T, Behrens T. Lung cancer and socioeconomic status in a pooled analysis of case-control studies. PLoS ONE 2018; 13: e0192999 IF: 3.700

574. *Schmitt J, Haufe E, Trautmann F, Schulze H-J, Elsner P, Drexler H, Bauer A, Letzel S, John SM, Fartasch M, Brüning T, Seidler A, Dugas-Breit S, Gina M, Weistenhöfer W, Bachmann K, Bruhn I ....Zimmermann, E. Is UV-exposure acquired at work the most important risk factor for cutaneous squamous cell carcinoma? Results of the population-based case-control study FB-181. Brit J Dermatol 2018; 178: 462 - 472 IF: 10.300

573. *Lessmann F, Bury D, Weis T, Hayen H, Brüning T, Koch HM. De-novo identification of specific exposure biomarkers of the alternative plasticizer di(2-ethylhexyl) terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS. Biomarkers 2018; 23: 196-206 IF: 2.600

572. *Pesch B, Lehnert M, Weiß T, Kendzia B, Menne E, Lotz A, Heinze E, Behrens T, Gabriel S, Schneider W, Brüning T. Exposure to hexavalent chromium in welders: Results of the WELDOX II field study. Ann Work Expos Health 2018; 62: 35100 361 IF: 2.600

571. *Monsé C, Hagemeyer O, Raulf M, Jettkant B, van Kampen V, Kendzia B, Gering V, Kappert G, Weiß T, Ulrich N, Marek EM, Bünger J, Brüning T, Merget R. Conncentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers. Particle and Fibre Tox 2018; 15: 8 IF: 10.000

570. *Krauß S, Yosef H, Lechtonen T, Jütte H, Tannapfel A, Käfferlein HU, Brüning T, Roghmann F, Noldus J, El-Mashtoly S, Gerwert K, Mosig A. Integrating spatial, morphological, and textural information for improved cell type differentiation using Raman microscopy. J Chemometrics 2018; 32: e2973 IF: 2.400

569. *Casjens S, Dydak U, Dharmadhikari S, Lotz A, Lehnert M, Quetscher C, Stewig C, Glaubitz B, Schmidt-Wilcke T, Edmondson D, Yeh CL, Weiß T, van Thriel C, Herrmann L, Muhlack S, Woitalla D, Aschner M, Brüning T, Pesch B. Association of exposure to manganese and iron with striatal and thalamic GABA and other neurometabolites - Neuroimaging results from the WELDOX II study. Neurotox 2018; 64: 60-67 IF: 3.400

568. *Rudolph A, ...Brüning T, Mannermaa A, Kosma VM, Lambrechts D, Keupers M, Couch FJ, Vachon C, Giles GG, ...Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. Int J Epidemiol. 2018; 47: 526 - 536 IF: 7.700

567. *Bury D, Belov V, Qi Y, Hayen H, Volmer DA, Brüning T, Koch HM. Determination of urinary metabolites of the emerging UV filter Octocrylene by online-SPE-LC-MS/MS. Anal Chem 2018; 90: 944-951 IF: 7.400

566. *Gleichenhagen J, Arndt C, Casjens S, Meinig C, Gerullis H, Raiko I, Brüning T

, Ecke T, Johnen G. Evaluation of a new Survivin ELISA and UBC® rapid for the detection of bladder cancer in urine. Int J Mol Sci. 2018; 19 pii: E226 IF: 5.600

565. *Pesch B, Dydak U, Lotz, Casjens S, Quetscher C, Lehnert M, Abramowski J, Stewig C, Yeh CL, Weiß T, van Thriel C, Herrmann L, Muhlack S, Woitalla D, Glaubitz B, Schmidt-Wilcke T, Brüning T. Association of exposure to manganese and iron with relaxation rates R1 and R2*- magnetic resonance imaging results from the WELDOX II study. Neurotox 2018; 64: 68-77 IF: 3.400

564.*Merget R, Sander I, Fartasch M, van Kampen V, Röseler S, Merk HF, Wurpts G, Raulf M, Brüning T. Occupational generalized urticaria and anaphylaxis after inhalation of cefuroxime in a nurse. Am J Ind Med 2018; 61: 261-266 IF: 3.500

563. *Jiao X, Aravidis C, ..., Brauch H, Brenner H, Broeks A, Brüning T, Burwinkel B,..., Hamann U, ... Czene K, Hall P, Lindblom A. PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget 2017; 8: 102769-102782 IF: 5.168

562. *Raulf M, Brüning T, Jensen-Jarolim E, van Kampen V. Gender-related aspects in occupational allergies – Secondary publication and update. World Allergy Organ J 2017; 10: 284 IF: 5.100

561. *Bauer AK, Velmurugan K, Plöttner S, Siegrist KJ, Romo D, Welge P, Brüning T, Xiong KN, Käfferlein HU. Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model. Arch Toxicol. 2017; 92: 1311 - 1322 IF:6.100

560. *Lang K, Bonberg N, Robens S, Behrens T, Hovanec J, Deix T, Braun K, Roghmann F, Noldus J, Harth V, Jöckel KH, Erbel R, Chun Tam Y, Tannapfel A, Käfferlein HU, Brüning T. Soluble chemokine (C-X-C motif) ligand 16 (CXCL16) in urine as a novel biomarker candidate to identify high grade and muscle invasive urothelial carcinomas. Oncotarget 2017; 8: 104946-104959 IF: 5.168

559. *Schmitt J, Haufe E, Trautmann F, Sch3l20H-J, Elsner P, Drexler H, Bauer A, Letzel S, John SM, Fartasch M, Brüning T, Seidler A, Dugas-Breit S, Gina M, Weistenhöfer W, Bachmann K, Bruhn I, Lang BM, Bonness S, Allam, JP, Grobe W, Stange T, Westerhausen, S, Knuschke P, Wittlich M, Diepgen TL. Occupational UV-exposure is a Major Risk Factor for Basal Cell Carcinoma. Results of the Population-Based Case-Control Study FB-181. J Occup Environ Med 2017; 60: 36 - 43 IF: 3.200

558. Kendzia B, van Gelder R, Schwank T, Hagemann C, Zschiesche W, Behrens T, Weiß T, Brüning T, Pesch B. Occupational Exposure to Inhalable Manganese at German Workplaces. Ann Work Expos Health 2017; 61: 1108-1117 IF: 2.600

557. *Marek EM, Koslitz S, Weiß T, Fartasch M, Schlüter G, Käfferlein HU, Brüning T. Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions. Arch Tox 2017; 91: 3587-3596 IF: 6.100

556. *Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, ..., Brooks-Wilson A, Brunet J, Brüning T, Burwinkel B, Buys SS, Byun J, Cai Q, Caldés T, Caligo MA, Campbell I, Canzian F, Caron O, Carracedo A, Carter BD, Castelao JE, Castera L, ..., Easton DF, Kraft P, Chenevix-Trench G, García-Closas M, Schmidt MK, Antoniou AC, Simard J. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics 2017; 49: 1767-1778 IF: 30.800

555. *Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, ..., Brauch H, Brennan P, Brenner H, Brinton L, Broberg P, Brock IW, Broeks A, Brooks-Wilson A, Brucker SY, Brüning T, Burwinkel B,..., Chanock SJ, Dunning AM, Edwards SL, Bader GD, Chenevix-Trench G, Simard J, Kraft P, Easton DF. Association analysis identifies 65 new breast cancer risk loci. Nature 2017; 551: 92-94 IF: 64.800

554. *Pesch B, Casjens S, Weiß T, Kendzia B, Arendt M, Eisele L, Behrens T, Ulrich N, Pundt N, Marr A, Robens S, van Thriel C, Van Gelder R, Aschner M, Moebus S, Dragano N, Brüning T, Jöckel KH. Occupational exposure to manganese and fine motor skills in elderly men. Results from the Heinz Nixdorf Recall Study. Ann Work Expos Health 2017; 61: 1118-1131 IF: 2.600

553. *Zahradnik E, Sander I, van Kampen V, Brüning T, Raulf M. Development of a quantitative immunoassay for Saccharopolyspora antigens. Allergologie 2017; 8: 306-310 IF: 0.500

552. *Casjens S, Weber DG, Johnen G, Raiko I, Taeger D, Meinig C, Moebus S, Jöckel KH, Brüning T, Pesch B. Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study. BMJ Open 2017; 7: e017104 IF: 2.900

551. *Behrens T, Rabstein S, Wichert K, Erbel R, Eisele L, Arendt M, Dragano N, Brüning T, Jöckel K-H. Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study. Scand J Work Environ Health 2017; 52: 670-681 IF: 6.300

550. *Kendzia B, Pesch B, Koppisch D, van Gelder R, Pitzke K, Zschiesche W, Behrens T, Weiß T, Siemiatycki J, Lavoue J, Jöckel K-H, Stamm R, Brüning T. Modelling of occupational exposure to inhalable nickel compounds. J Expo Sci Environ Epidemiol 2017; 27: 427-433 IF: 4.500

549. *Hessam S, Sand M, Lang K, Käfferlein HU, Scholl L, Gambichler T, Skrygan M, Brüning T, Stockfleth E, Bechara FG. Altered global 5-Hydroxymethylation status in Hidradenitis Suppurativa. Support for an epigenetic background. Dermatology 2017; 233: 129-135 IF: 3.400

548. *Raulf M, Brüning T, van Kampen V. Berufliche Allergien: Inwieweit spielen Genderaspekte eine Rolle? Allergologie 2017; 40: 117–127 IF: 0.500

547. *Bigert C, Gustavsson P, Straif K, Schüz J, Olsson A, Taeger D, Brüning T. Response to "Lung cancer among non-smoking firefighters". J Occup Environ Med 2017 ; 59: e69 IF: 3.200

546. *Johnen G, Gawrych K, Raiko I, Casjens S, Pesch B, Weber DG, Taeger D, Lehnert M, Kollmeier J, Bauer T, Musk AW, Robinson BWS, Brüning T, Creaney J
Calretinin as a blood-based biomarker for mesothelioma.
BMC Cancer 2017; 386: 1-11 IF: 3.800

545. *Yosef H, Krauß SD, Lechtonen T, Jutte H, Tannapfel A, Käfferlein HU, Brüning T, Roghmann F, Noldus J, Mosig A, El-Mashtoly SF, Gerwert K
Non-invasive Diagnosis of High-grade Urothelial Carcinoma in Urine by Raman Spectral Imaging.
Anal Chem 2017; 89: 6893-6899 IF: 7.400

544. *Mielke S, Taeger D, Weitmann K, Brüning T, Hoffmann W
Influence of quartz exposure on lung cancer types in cases of lymph node-only silicosis and lung silicosis in German uranium miners.
Arch Environ Occup Health 2018; 26: 1-14 IF: 1.800

543. *Day F, Thompson D, Helgason H,...., Brauch H, Brenner H, Broer L, Brüning T, ...., Murray A
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
Nat Genet 2017; 49: 834-841 IF: 30.800

542. *Bonberg N, Pesch B, Ulrich N, Moebus S, Eisele L, Marr A, Arendt M, Jöckel KH, Brüning T, Weiß T
The distribution of blood concentrations of lead (Pb), cadmium (Cd), chromium (Cr) and manganese (Mn) in residents of the German Ruhr area and its potential association with occupational exposure in metal industry and/or other risk factors.
Int J Hyg Environ Health 2017; 220: 998-1005 IF: 6.000

541. *Weber DG, Gawrych K, Casjens S, Brik A, Lehnert M, Taeger D, Pesch B, Kollmeier J, Bauer TT, Johnen G, Brüning T
Circulating miR-132-3p as a candidate diagnostic biomarker for malignant mesothelioma.
Dis Markers 2017; 9280170 IF: 3.464

540. *Raulf M, van Kampen V, Neumann HD, Liebers V, Deckert A, Brüning T, Bünger J, Hoffmeyer F.
Airway and Blood Inflammatory Markers in Waste Collectors.
Adv Exp Med Biol 2017; 1021: 1-14 IF: 3.650

539. Raiko I, Rihs HP, Gleichenhagen J, Sander I, Kollmeier J, Lehnert M, Brüning T, Johnen G.
A recombinant polypeptide of the megakaryocyte potentiatinactor is a potential biomarker in plasma for the detection of mesothelioma.
Biochem Biophys Res Commun 2017; 486: 526-532 IF: 3.100

538. Liebers V, Kendzia B, Düser M, Brüning T, Raulf M.
Bestimmung der Endotoxin-Aktivität - Methodische Aspekte.
Gefahrstoffe - Reinhaltung der Luft 2017; 77: 143-150 IF: 0.300

537. Lessmann F, Correia-Sa L, Calhau C, Domingues VF, Weiß T, Brüning T, Koch HM.
Exposure to the plasticizer di(2-ethylhexyl) terephthalate (DEHTP) in Portuguese children - Urinary metabolite levels and estimated daily intakes.
Environ Int 2017; 104: 25-32 IF: 11.800

536. Kleinbeck S, Schaper M, Zimmermann A, Blaszkewicz M, Brüning T, van Thriel C.
Prediction of human sensory irritation due to ethyl acrylate: the appropriateness of time-weighted average concentration x time models for varying concentrations.
Arch Toxicol 2017; 91: 3051-3064 IF: 6.100

535. Hoffmeyer F, Sucker K, Berresheim H, Monsé C, Jettkant B, Beine A, Raulf M, Bünger J, Brüning T.
Impact of Internal and External Factors on EBC-pH and FeNO Changes in Humans Following Challenge with Ethyl Acrylate.
Adv Exp Med Biol 2017; 1020: 7-16 IF: 3.650

534. Gambichler T, Kohsik C, Hoh AK, Lang K, Käfferlein HU, Brüning T, Stockfleth E, Stucker M, Dreissigacker M, Sand M.
Expression of PIWIL3 in primary and metastatic melanoma.
J Cancer Res Clin Oncol 2017; 143: 433-437 IF: 3.600

533. Großerüschkamp F, Bracht T, Diehl HC, Kuepper C, Ahrens M, Kallenbach-Thieltges A, Mosig A, Eisenacher M, Marcus K, Behrens T, Brüning T, Theegarten D, Sitek B, Gerwert K.
Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics.
Sci. Rep 2017; 7: 44829 IF: 4.600

532. Shimelis H, Mesman RL, Von Nicolai C, Ehlen A, ... Brauch H, Brennan P, Brenner H, Broeks A, Brouwers B, Brüning T, Burwinkel B, Chang-Claude J, Chenevix-Trench G, Cheng CY, Choi JY, Collée JM, Cox A, Cross SS, ..., Hamann U, Hartman M, Hogervorst FB, ..., Vrieling H, Monteiro AN, Goldgar DE, Carreira A, Vreeswijk MP, Couch FJ.
BRCA2 hypomorphic missense variants confer moderate risks of breast cancer.
Cancer Res 2017: 77: 2789-2799 IF: 11.200

531. Raulf M, Brüning T, van Kampen V
Berufliche Allergien: Inwieweit spielen Genderaspekte eine Rolle?
Allergologie 2017; 40: 117-127 IF: 0.500

530. *Lehnert M, Kraywinkel K, Heinze E, Wiethege T, Johnen G, Fiebig J, Brüning T, Taeger D
Incidence of malignant mesothelioma in Germany 2009–2013.
Cancer Causes Control 2017; 28: 97-105 IF: 2.532

529. *van Thriel C, Quetscher C, Pesch B, Lotz A, Lehnert M, Casjens S, Weiß T, Van Gelder R, Plitzke K, Brüning T, Beste C; WELDOX II Study Group.
Are multitasking abilities impaired in welders exposed to manganese? Translating cognitive neuroscience to neurotoxicology.
Arch Tox 2017; 91: 2865-2877 IF: 6.168

528. *Olsson AC, Vermeulen R, Schüz J, Kromhout H, Pesch B, Peters S, Behrens T, Portengen L, Mirabelli D, Gustavsson P, Kendzia B, Almansa J, Luzon V, Vlaanderen J, Stücker I, Guida F, Consonni D, Caporaso N, Landi MT, Field J, Brüske I, Wichmann HE, Siemiatycki J, Parent ME, Richiardi L, Merletti F, Jöckel KH, Ahrens W, Pohlabeln H, Plato N, Tardón A, Zaridze D, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Stanescu Dumitru R, Bencko V, Foretova L, Janout V, Boffetta P, Bueno-de-Mesquita B, Forastiere F, Brüning T, Straif K.
Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies.
Epidemiology 2017; 28: 288-299 IF: 4.860

527. *Rotter M, Brandmaier S, Prehn C, Adam J, Rabstein S, Gawrych K, Brüning T, Illig T, Lickert H, Adamski J, Wang-Sattler R:
Stability of targeted metabolite profiles of urine samples under different storage conditions.
Metabolomics 2017; 13: 4IF: 4.747

526. *Merget R, Pham N, Schmidtke M, Casjens S, van Kampen V, Sander I, Hagemeyer O, Sucker K, Raulf M, Brüning T:
Medical surveillance and long-term prognosis of occupational allergy due to platinum salts.
Int Arch Occup Environ Health 2017; 90: 73-81 IF: 2.851

525. *Schütze A, Otter R, Modick H, Langsch A, Brüning T, Koch HM:
Additional oxidized and alkyl chain breakdown metabolites of the plasticizer DINCH in urine after oral dosage to human volunteers.
Arch Toxicol 2017; 91: 179-188 IF: 6.168

524. *Koch HM, Rüther M, Schütze A, Conrad A, Pälmke C, Apel P, Brüning T, Kolossa-Gehring M:
Phthalate metabolites in 24-h urine samples of the German Environmental Specimen Bank (ESB) from 1988 to 2015 and a comparison with US NHANES data from 1999 to 2012.
Int J Hyg Environ Health 2017; 220: 130-141 IF: 7.401

523.* Sander I, Neumann HD, Lotz A, Czibor C, Zahradnik E, Flagge A, Faller I, Buxtrup M, Brüning T, Raulf M:
Allergen quantification in surface dust samples from German day care centers.
J Toxicol Env Health, Part A 2016; 79: 1094-1105 IF: 1.036

522. *Raulf M, Weiß T, Lotz A, Lehnert M, Hoffmeyer F, Liebers V, Van Gelder R, Käfferlein HU, Hartwig A, Pesch B, Brüning T:
Analysis of inflammatory markers and metals in nasal lavage fluid of welders.
J Toxicol Env Health, Part A 2016; 79: 1144-1157 IF: 1.036

521. *Kespohl S, Campo P, Zahradnik E, Maryska S, Aranda-Guerrero A, Rodriguez J, Brüning T, Raulf M:
Quantification of obeche wood allergen: Development of a sensitive sandwich-ELISA for occupational exposure assessment.
J Toxicol Env Health, Part A 2016; 79: 1070-1077 IF: 1.036

520. *Moos R, Apel P, Schröter-Kermani C, Kolossa-Gehring M, Brüning T, Koch HM:
Daily intake and hazard index of parabens based upon 24 h urine samples of the German Environmental Specimen Bank from 1995 to 2012.
J Expo Sci Environ Epidemiol 2016; 27: 591-600 IF: 6.371

519. *Plöttner S, Bastian LA, Käfferlein HU, Brüning T:
Effects of benzo[a]pyrene, aromatic amines, and a combination of both on CYP1A1 activities in RT-4 human bladder papilloma cells.
J Toxicol Env Health, Part A 2016; 79: 1106-1117 IF: 1.036

518. *Casjens S, Pesch B, Robens S, Kendzia B, Behrens T, Weiß T, Ulrich N, Arendt M, Eisele L, Pundt N, Marr A, van Thriel C, van Gelder R, Aschner M, Moebus S, Dragano N, Jöckel K-H, Brüning T:
Associations between former exposure to manganese and olfaction in an elderly population: Results from the Heinz Nixdorf Recall Study.
Neurotoxicology 2016; 58: 58-65 IF: 4.398

517. *Bigert C, Gustavsson P, Straif K, Taeger D, Pesch B, Kendzia B, Schüz J, Stucker I, Guida F, Brüske I, Wichmann H-E, Pesatori A, Landi M, Caporaso N, Tse L, Yu I, Siemiatycki J, Lavoue J, Richiardi L, Mirabelli D, Simonato L, Jockel K-H, Ahrens W, Pohlabeln H, Tardon A, Zaridze D, Field J, Mannetje A 't, Pearce N, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Stanescu Dumitru R, Bencko V, Foretova L, Janout V, Boffetta P, Peters S, Vermeulen R, Kromhout H, Brüning T, Olsson A:
Lung Cancer Among Firefighters: Smoking-Adjusted Risk Estimates in a Pooled Analysis of Case-Control Studies.
J Occup Environ Medicine 2016; 58: 1137–1143 IF: 2.306

516. *Guo Y, Warren Andersen S, Shu X-O, Michailidou K, …, Brauch H, Brenner H, Brüning T, …,Kraft P, Pharoah P, Hunter D, Easton DF, Zheng W:
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
PLoS medicine 2016; 13: e1002105 IF: 11.613

515. *Taeger D, Gawrych K, Brüning T:
Validity of mesothelin in occupational medicine practice.
Int J Occup Med Environ Health 2016; 29 IF: 1.828

514. *Zaghow M, Sucker K, Pallapies D, Schlüter G, Brüning T:
Gefahrstoff-Forschung - Gerüche und Reizstoffe.
Gefahrstoffe - Reinhaltung der Luft 2016; 76: 383–386 IF: 0.158

513. *Zeng C, Guo X, Long J, Kuchenbaecker K, …, Brauch H, Brennan P, Brenner H, Broeks A, Brüning T,…, Dunning AM, Simard J, Couch FJ, Easton DF, Zheng W:
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Breast Cancer Res Tr 2016; 18: 64 IF: 4.624

512. *Darabi H, Beesley J, Droit A, Kar S, Nord S, Moradi Marjaneh M, Soucy P, Michailidou K,..., Brauch H, Brenner H, Broeks A, Brüning T,...Vincent D, Winqvist R, Wu AH, Wu PE, Yip CH, Zheng W, Pharoah PD, Hall P, Edwards SL, Simard J, French JD, Chenevix-Trench G, Dunning AM:
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
Sci Rep 2016; 6: 32512 IF: 4.996

511. *Schremmer I, Brik A, Weber DG, Rosenkranz N, Rostek A, Loza K, Brüning T, Johnen G, Epple M, Bünger J, Westphal GA:
Kinetics of chemotaxis; cytokine; and chemokine release of NR8383 macrophages after exposure to inflammatory and inert granular insoluble particles.
Toxicol Lett 2016; 263: 68-75 IF: 4.271

510. *Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD,... Brauch H, Brüning T,..., Kupryjanczyk J, Pharoah PD, Song H, Winship I, Chenevix-Trench G, Giles GG, Tavtigian SV, Easton DF, Milne RL:
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.
J Med Genet 2016; 53: 800-811 IF: 5.954

509. *van Kampen V, Hoffmeyer F, Deckert A, Kendzia B, Casjens S, Neumann HD, Buxtrup M, Willer E, Felten C, Schöneich R, Brüning T, Raulf M, Bünger J:
Effects of bioaerosol exposure on respiratory health in compost workers: a 13-year follow-up study.
Occup Environ Med 2016; 73: 829-837 IF: 4.961

508. *Lotz A, Pesch B, Dettbarn G, Raulf M, Welge P, Rihs H, Breuer D, Gabriel S, Hahn J, Brüning T, Seidel A:
Metabolites of the PAH diol epoxide pathway and other urinary biomarkers of phenanthrene and pyrene in workers with and without exposure to bitumen fumes.
Int Arch Occup Environ Health 2016; 89: 1251-1267 IF: 2.851

507. *Kar SP, Beesley J, Amin Ak Olama A, Michailidou K,... Brauch H, ...Brüning T,...,Easton DF, Chenevix-Trench G, Eeles R, Pharoah PD, Lambrechts D:
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.
Cancer Discov 2016; 6: 1052-1067 IF: 38.272

506. *van Kampen V, Brüning T, Merget R:
Occupational Allergies to Trypsin and Chymotrypsin.
Pneumologie 2016; 70: 442-445 IF: 0.28

505. *Behrens T, Groß I, Siemiatycki J, Conway D, Olsson A, Stücker I, Guida F, Jöckel KH, Pohlabeln H, Ahrens W, Brüske I, Wichmann HE, Gustavsson P, Consonni D, Merletti F, Richiardi L, Simonato L, Fortes C, Parent ME, McLaughlin J, Demers P, Landi M, Caporaso N, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, Lissowska J, Fabianova E, Tardón A, Field J, Dumitru R, Bencko V, Foretova L, Janout V, Kromhout H, Vermeulen R, Boffetta P, Straif K, Schüz J, Hovanec J, Kendzia B, Pesch B, Brüning T:
Occupational prestige, social mobility and the association with lung cancer in men.
BMC Cancer 2016; 16: 395 IF: 4.638

504. *Schmitz-Dräger C, Bonberg N, Pesch B, Todenhöfer T, Sahin S, Behrens T, Brüning T, Schmitz-Dräger BJ:
Replacing cystoscopy by urine markers in the follow-up of patients with low-risk non-muscle-invasive bladder cancer? An International Bladder Cancer Network project.
Urol Oncol 2016; 34: 452-459 IF: 0.818

503. *Monsé C, Sucker K, Hoffmeyer F, Jettkant B, Berresheim H, Bünger J, Brüning T:
The influence of humidity on assessing irritation threshold of ammonia.
Biomed Res Int 2016; 6015761 IF: 3.246

502. *Westphal GA, Rihs HP, Schaffranek A, Zeiler T, Werfel T, Heratizadeh A, Dickel H, Weisshaar E, Bauer A, Schliemann S, Reich K, Breuer K, Schröder-Kraft C, Worm M, Molin S, Brans R, Schäkel K, Schwantes H, Pföhler C, Szliska C, Kreft B, Löffler H, Bünger, J, Brüning T, Geier J, Schnuch A:
A variant of the CXCL11 gene may influence susceptibility to contact allergy, particularly in polysensitized patients.
Contact Dermatitis 2016; 75: 303-307 IF: 6.419

501. *Schmidt MK, Hogervorst F, van Hien R, Cornelissen S, ..., Brauch H, Brenner H, Brüning T, ..., Dörk T, Bojesen S, Easton DF:
Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
J Clin Oncol 2016; 34: 2750-60 IF: 50.769

500. *Peters S, Vermeulen R, Portengen L, Olsson A, Kendzia B, Vincen, R, Savary B, Lavoue J, Cavallo D, Cattaneo A, Mirabelli D, Plato N, Fevotte J, Pesch B, Brüning T, Straif K, Kromhout H:
SYN-JEM: A quantitative job-exposure matrix for five lung carcinogens.
Ann Occup Hyg 2016; 60: 795-811 IF: 2.241

499. *Monsé C, Sucker K, Hoffmeyer F, Jettkant B, Berresheim H, Bünger J, Brüning T:
The Influence of Humidity on Assessing Irritation Threshold of Ammonia.
Biomed Res Int 2016; ID 6015761 IF: 3.246

498. *Bünger J, Bünger JF, Krahl J, Munack A, Schröder O, Brüning T, Hallier E, Westphal GA:
Combusting vegetable oils in diesel engines: the impact of unsaturated fatty acids on particle emissions and mutagenic effects of the exhaust.
Arch Tox 2016; 90: 1471-1479 IF: 6.168

497. *Pelttari LM, Khan S, Vuorela M, Kiiski JI, Vilske S, Nevanlinna V, ..., Brauch H, Brüning T,... Couch FJ, Yannoukakos D, Orr N, Swerdlow A, Darabi H, Li J, Czene K, Hall P, Easton DF, Mattson J, Blomqvist C, Aittomäki K, Nevanlinna H:
RAD51B in Familial Breast Cancer.
PlosOne 2016; 11(5):e0153788 IF: 3.752

496. *Lessmann F, Schütze A, Weiß T, Langsch A, Otter R, Brüning T, Koch HM:
Metabolism and urinary excretion kinetics of di(2-ethylhexyl) terephthalate (DEHTP) in three male volunteers after oral dosage.
Arch Toxicol 2016; 90: 1659-1667 IF: 6.168

495. *Shi J, Zhang Y, Zheng W, Michailidou K, ..., Brauch H, Brenner H, Brinton L, Broeks A, Brüning T, ..., Dunning AM, Antoniou AC, Easton DC, Cai Q, Long J:
Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.
Int J Cancer 2016; 139: 1303-1317 IF: 7.316

494. Kespohl S, Ochsmann U, Kotschy-Lang N, Maryska S, Nowak D, Brüning T, Raulf M.
Diagnostic algorithm for IgE-mediated wood dust allergy.
Allergologie 2016; 39: 168-174 IF: 0.238

493. *Brüning T, Welge P, Plöttner S, Hagemeyer O, Weiß, Van Gelder R, Bünger J:
Arbeiten unter Einwirkung von Quecksilber und seinen Verbindungen.
Arbeitsmed Sozialmed Umweltmed 2016; 51: 292-296

492. *Käfferlein HU, Stamm R, Dörr R, Brüning T: Abbeizer
Gefahrstoffe Reinhaltung Luft 2016; 76: 146-147 IF: 0.158

491. *Hoffmeyer F, van Kampen V, Schantora AL, Deckert A, Neumann HD, Brüning T, Raulf M, Bünger J:
Gesundheitsbeeinträchtigungen bei aktuell und ehemals Beschäftigten der Abfallsammlung.
Arbeitsmed Sozialmed Umweltmed 2016; 51: 276-285

490. *Taeger D, McCunney R, Bailer U, Barthel K, Küpper U, Brüning T, Morfeld P, Merget R:
Cross-sectional study on nonmalignant respiratory morbidity due to exposure to synthetic amorphous silica.
J Occup Environ Med. 2016; 58: 376-384 IF: 2.306

489. *Kespohl S, Maryska S, Bünger J, Hagemeyer O, Jakob T, Joest M, Knecht R, Koschel D, Kotschy-Lang N, Merget R, Mülleneisen NK, Rabe U, Röseler S, Sander I, Stollewerk D, Straube H, Ulmer HM, van Kampen V, Walusiak-Skorupa J, Wiszniewska M, Wurpts G, Brüning T, Raulf M:
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results.
Clin Exp Allergy 2016; 46: 981-991 IF: 5.401

488. *Codas M, Pesch B, Adolphs M, Madrazo C, Matthias C, Heinze E, Taeger D, Behrens T, Chaux A, Brüning T:
Cancer mortality in Itapúa-A rural province of Paraguay 2003-2012.
Cancer Epidemiol 2016; 40: 1-6 IF: 2.890

487. *Petridis C, Brook MN, Shah V, ... Brüning T, Brauch H, Southey MC, ...,Roylance R, Garcia-Closas M, Sawer EJ:
Genetic predisposition to ductal carcinoma in situ of the breast.
Breast Cancer Res 2016; 18 IF: 8.408

486. *Sander I, Rihs HP, Brüning T, Raulf M:
A further wheat allergen for baker's asthma: Tri a 40.
J Allergy Clin Immunol 2016; 137: 1286 IF: 14.290

485. *Merget R, Sander I, van Kampen V, Raulf M, Brüning T:
Triticale allergy in a farmer.
Am J Ind Medicine 2016; 59: 501-509 IF: 3.079

484. *Lessmann F, Schütze A, Weiß T, Brüning T, Koch HM:
Determination of Metabolites of Di(ethylhexyl)-terephthalate (DEHTP) in Human Urine by HPLC-MS/MS with On-line Clean-up.
J. Chrom B 2016; 1011: 196-203 IF: 1.911

483. *Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, and Consortium of Modifiers of BRCA1 and BRCA2, Hollestelle A, van der Baan FH, Berchuck A, Johnatty SE, ..., Brüning T,..., Winqvist R, Wu AH, Wu X, Yang HP, Zaffaroni D, Pilar Zamora M, Zheng W, Ziogas A, Chenevix-Trench G, Pharoah PD, Rookus MA, Hooning MJ, Goode EL.:
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Gynecol Oncol 2016; 141: 386-401 IF: 5.304

482. *Modick H, Weiß T, Dierkes G, Koslitz S, Käfferlein HU, Brüning T, Hoch HM:
Human metabolism and excretion kinetics of aniline after a single oral dose.
Arch Tox 2016; 90: 1325-1333 IF: 6.168

481. *Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, Wang Q, ..., Brauch H, Brüning T,..., Easton DF, Couch FJ, Spurdle AB, Goldgar DE.
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
J Natl Cancer Inst 2016; 108 (2): djv315 IF: 13.757

480. *Moos RK, Angerer J, Dierkes G, Brüning T, Koch HM:
Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage.
Arch Tox 2015; 218: 666-74 IF: 6.168

479. *Day FR, Ruth KS, Thompson DJ, Lunetta KL, ..., Brenner H, Brüning T,..., , Ulivi S, Völzke H, Wareham NJ, Weir DR, Yerges-Armstrong LM; PRACTICAL Consortium; kConFab Investigators; AOCS Investigators; Generation Scotland; EPIC-InterAct Consortium; LifeLines Cohort Study, Price AL, Stefansson K, Visser JA, Ong KK, Chang-Claude J, Murabito JM, Perry JR, Murray A:
Nat Genet 2015; 47: 1294-1303 IF: 41.379

478. *Brüning T, Pesch B, Zschiesche W, Welge P, Hagemeyer F, Weiß T, Schlüter G, Nies E, Bochmann F, Stamm R, Palfner S, Pallapies D:
Wissenschaftliche Datenlage zur BK-Nr. 1103 im Hinblick auf die kanzerogene Wirkung von Chrom(VI)-Verbindungen.
Arbeitsmed Sozialmed Umweltmed 2015; 50: 666-676

477. *Zhang B, Shu XO, Delahanty RJ, Zeng C, Michailidou K, Bolla MK, Wang Q, Dennis J, Wen W, Long J, Li C, Dunning AM...,Brauch H, Brüning T,...,Hall P, Hunter DJ, Easton DF, Zheng W :
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.
J Natl cancer Inst 2015; 107: pii:djv219 IF: 13.757

476. *Monsé C, Hahn JU, Assenmacher-Maiworm H, Kessler G, Bünger J, Brüning T, Merget R:
Validation of a new paper-tape monitor for the quasi-continuous determination of airborne diisocyanate concentrations.
Env & Anal Toxicol 2015; 5: 4

475. *Moos R, Koch HM, Angerer J, Apel P, Schröter-Kermani C, Brüning T, Kolossa-Gehring M:
Parabens in 24 h urine samples of the German Environmental Specimen Bank from 1995 to 2012.
Int. J. Hyg. Environ Health 2015; 218: 666-674 IF: 7.401

474. *Taeger D, Pesch B, Kendzia B, Behrens T, Jöckel KH, Dahmann D, Siemiatycki J, Kromhout H, Vermeulen R, Peters S, Olsson A, Brüske I, Wichmann HE, Stücker I, Guida F, Tardón A, Merletti F, Mirabelli D, Richiardi L, Pohlabeln H, Ahrens W, Landi MT, Caporaso N, Pesatori AC, Mukeriya A, Szeszenia-Dabrowska N, Lissowska J, Gustavsson P, Field J, Marcus MW, Fabianova E, 't Mannetje A, Pearce N, Rudnai P, Bencko V, Janout V, Dumitru RS, Foretova L, Forastiere F, John McLaughlin JM, Paul Demers PD, Bas Bueno-de-Mesquita BB, Joachim Schüz JS, Kurt Straif KS, Brüning T:
Lung cancer among coal miners, ore miners and quarrymen: smoking-adjusted risk estimates from the synergy pooled analysis of case-control studies.
Scand J Work Environ Health 2015; 41: 467-477 IF: 5.492

473. *Zahradnik E, Sander I, Brüning T, Raulf M:
Allergen Levels in the Hair of Different Cattle Breeds.
Int Arch Allergy Immunol 2015; 167: 9-15 IF: 3.767

472. *Schütze A, Gries W, Kolossa-Gehring M, Apel P, Schröter-Kermani C, Fiddicke U, Leng G, Brüning T, Koch HM:
Bis(2-propylheptyl)phthalate (DPHP) metabolites emerging in 24h urine samples from the German Environmental Specimen Bank (1999 to 2012).
Int J Hyg Environ Health 2015; 218: 559-563 IF: 7.401

471. *Hagemeyer O, Marek E, van Kampen V, Sander I, Raulf M, Merget R, Brüning T.
Specific inhalation challenge in Persulfate asthma.
Adv Exp Med Biol 2015; 861: 85-91 IF: 3.650

470. *Merget R, Fartasch M, Sander I, Van Kampen V, Raulf M, Brüning T:
Eosinophilic airway disease in a patient with a negative skin prick test, but a positive patch test with platinum salts - implications for medical surveillance.
Am J Ind Med 2015; 58: 1008-1011 IF: 3.079

469. *Raulf M, Bergmann KC, Kull S, Sander I, Hilger C, Brüning T, Jappe U, Müsken H, Sperl A, Vratal S, Zahradnik E, Klimek L.:
Mites and other indoor allergens — from exposure to sensitization and treatment.
Allergo J Int 2015; 24: 68-80 IF: 0.35

468. *Hoffmeyer F, Berresheim H, Beine A, Sucker K, Brüning T, Bünger J:
Methodological implications in pH standardization of exhaled breath condensate.
J Breath Res 2015; 14: 036003 IF: 2.922

467. *Pesch B, Kendzia B, Hauptmann K, Van Gelder R, Stamm R, Hahn JU, Zschiesche W, Behrens T, Weiß T, Siemiatycki J, Lavoué J, Jöckel KH, Brüning T:
Airborne exposure to inhalable hexavalent chromium in welders and other occupations: Estimates from the German MEGA database.
Int J Hyg Env Health 2015; 218: 500-506 IF: 7.401

466. *Westphal GA, Schremmer I, Rostek A, Loza K, Rosenkranz N, Brüning T, Epple M, Bünger J:
Particle-induced cell migration assay (PICMA): a new in vitro assay for inflammatory particle effects based on permanent cell lines.
Toxicol In vitro 2015; 29: 997-1005 IF: 3.685

465. *Rihs HP, Sander I, Heimann H, Meurer U, Brüning T, Raulf M:
The new latex allergen Hev b 15: IgE-Binding properties of a recombinant serine protease inhibitor.
J Invest Allergol Clin Immunol 2015; 25: 160-162 IF: 8.185

464. *Mavaddat N, Pharaoah PD, Michailidou K,...,Brauch H , Brüning T, Ko YD, ..., Hall P, Easton DF, Garcia-Closas M.:
Prediction of breast cancer risk based on profiling with common genetic variants.
J Natl Cancer Inst 2015; 107: djv036 IF: 13.757

463. *Painter JN, O'Mara T,...,Brauch H , The GENICA Network,..., Johnson N, Peto J:
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Hum Mol Genet 2015; 24; 1478-1492 IF: 5.121

462. *Hoffmeyer F, van Kampen V, Deckert A, Neumann HD, Buxtrup M, Willer E, Felten C, Brüning T, Raulf M, Bünger J:
Evaluation of Airway Inflammation in Compost Workers Exposed to Bioaerosols Using Exhaled Breath Condensate and Fractional Exhaled Nitric Oxide.
Adv Exp Med Biol 2015; 858: 57-67 IF: 3.650

461. *van Kampen V, Sander I, Quirce S, Brüning T, Merget R, Raulf M.:
IgE Sensitization to Lupine in Bakers - Cross-Reactivity or Co-Sensitization to Wheat Flour?
Int Arch Allergy Immunol 2015; 166: 63-70 IF: 3.767

460. *Michailidou K, Beesley J, Lindstrom S, Canisius S, Dennis J..., Brauch H, Hamann U, Brüning T, GENICA Network, ..., Hall P, Easton DF:
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nat Genet 2015; 47: 373-380 IF: 41.379

459. *Monsé C, Hahn J-U, Assenmacher-Maiworm H, Keßler G, Brüning T, Merget R:
Determing the concentration of diisocyanate atmospheres during inhalative exposure tests.
Gefahrstoffe - Reinhaltung der Luft 2015; 75: 95-100 IF: 0.158

458. *Punsmann S, Liebers V, Brüning T, Raulf M:
Can mold exposure affect the innate immune system? Summary of the results of a pilot study.
Allergologie 2015; 38: 91-102 IF: 0.238

457. *Raulf M, Sander I, Hilger C, Brüning T, Zahradnik E:
Pests and other undiserable subtenants - how relevant are they as indoor allergen source?
Allergologie 2015; 38: 103-108 IF: 0.238

456. *Sander I, Zahradnik E, Brüning T, Raulf M:
Quantification of mite exposure in homes with different immunoassays and airborne dust sampling methods.
Allergologie 2015; 38: 64-69 IF: 0.238

455. *Schütze A, Lorber M, Gawryh K, Kolossa-Gehring M, Apel P, Brüning T, Koch HM:
Development of a multi-compartment pharmacokinetic model to characterize the exposure to Hexamoll® DINCH®.
Chemosphere 2015; 128: 216-224 IF: 8.943

454. *Behrens T, Brüning T, Pesch B:
Tumormarkerforschung für die klinische Praxis.
Onkologe 2015; 21: 250-256 IF: 0.170

453. *Orr N, Dudbridge F, Dryden N, Maguire S, Novo D, Perrakis E, Johnson N, Ghoussaini M, Hopper JL, Southey MC, Apicella C, ..., Hamann U, Brauch H, Justenhoven C, Brüning T, Ko YD; The GENICA Network, Nevanlinna H, ..., Michailidou K, Bolla MK, Easton DF, Dos Santos Silva I, Fletcher O, Peto J.
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
Hum Mol Genet 2015; 24: 2966-2984 IF: 5.121

452. *Bigert C, Gustavsson P, Straif K, Pesch B, Brüning T, Kendzia B, Schüz J, Stücker I, Guida F, Brüske I, Wichmann HE, Pesatori AC, Landi MT, Caporaso N, Tse LA, Yu IT, Siemiatycki J, Pintos J, Merletti F, Mirabelli D, Simonato L, Jöckel KH, Ahrens W, Pohlabeln H, Tardón A, Zaridze D, Field J, ʼt Mannetje A, Pearce N, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Stanescu Dumitru R, Bencko V, Foretova L, Janout V, Boffetta P, Forastiere F, Bueno-de-Mesquita B, Peters S, Vermeulen R, Kromhout H, Olsson AC
Lung cancer risk among cooks when accounting for tobacco smoking: a pooled analysis of case-control studies from europe, Canada, new zealand, and china.
J Occup Env Med 2015; 57: 202-209 IF: 2.306

451. *Raulf M, Hoffmeyer F, van Kampen V, Deckert A, Brüning T, Brüning T, Bünger J:
Cellular and Soluble Inflammatory Markers in Induced Sputum of Composting Plant Workers.
Adv Exp Med Biol. 2015; 858: 19-29 IF: 3.650

450. *Kabisch M, Bermejo JL, Dünnebier T, Ying S, Michailidou K, Bolla MK, Wang Q, Dennis J, Shah M,...,Brauch H, Brüning T, Ko YD, The GENICA Network,..., Dunning AM, Easton DF, Hamann U:
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER negative breast cancer.
Carcinogenesis 2015; 36: 256-271 IF: 4.741

449. *Weiß T, Schindler BK, Schütze A, Koslitz S, Broding HC, Bünger J, Brüning T
Reply to the letter of Anderson J entitled "Comment on Schindler, BK; Weiß, T; Schütze, A; et al. Occupational exposure of air crews to tricresyl phosphate isomers and organophosphate flame retardants after fume events.
Arch Toxicol 2013; 87:645-648
Arch Tox 2015; 36: 256-271 IF: 6.168

448. *Sander I, Rihs HP, Doekes G, Quirce S, Krop E, Rozynek P, van Kampen V, Merget R, Meurer U, Brüning T, Raulf M
Component-resolved diagnosis of baker's allergy based on specific IgE to recombinant wheat flour proteins.
J Allergy Clin Immunol 2015; 135: 1529-1536 IF: 14.290

447. *Liebers V, Bachmann D, Franke G, Freundt S, Stubel H, Düser M, Kendzia B, Böckler M, Brüning T, Raulf M
Determination of ATP-activity as a useful tool for monitoring microbial load in aqueous humidifier samples.
Int J Hyg Environ Health 2015;218: 246-253 IF: 7.401

446. *Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O'Reilly,..., Brauch H, Ko Y, Brüning T, The GENICA Network,..., Thompson DJ, Edwards SL, Easton DF, Dunning AM, French JD.Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1. Am J Hum Genet 2015; 96: 5-20 IF: 9.800

445. *Großerüschkamp F, Kallenbauch-Thieltges A, Behrens T, Brüning T, Altmayer M, Stamatis G, Theegarten D, Gerwert K. Marker‐free automated histopathological annotation of lung tumour subtypes by FTIR‐Imaging. Analyst 2015; 140: 2465-2472 IF: 4.200

444. *Lehnert M, Hoffmeyer F, Gawrych K, Lotz A, Heinze E, Berresheim H, Merget R, Harth V, Van Gelder R, Hahn JU, Hartwig A, Weiß T, Pesch B, Brüning T; for the WELDOX Study Group. Effects of Exposure to Welding Fume on Lung Function: Results from the German WELDOX Study. Adv Exp Med Biol 2015; 834: 1-13 IF: 3.650

443. *Hoffmeyer F, Sucker K, Monsé C, Berresheim H, Jettkant B, Rosenkranz N, Brüning T, Bünger J. Different Patterns in Changes of Exhaled Breath Condensate pH and Exhaled Nitric Oxide After Ozone Exposure. Adv Exp Med Biol 2015; 834: 39-47 IF: 3.650

442. *Schantora A, Casjens S, Deckert A, van Kampen V, Neumann HD, Brüning T, Raulf M, Bünger J, Hoffmeyer F. Prevalence of Work-Related Rhino-Conjunctivitis and Respiratory Symptoms Among Domestic Waste Collectors. Adv Exp Med Biol 2015; 834: 53-61 IF: 3.650

441. *Merget R, Sander I, van Kampen V, Raulf M, Hagemeyer O, Marek E, Brüning T.
Serial Measurements of Exhaled Nitric Oxide at Work and at Home: A New Tool for the Diagnosis of Occupational Asthma. Adv Exp Med Biol 2015; 834: 49-52 IF: 3.650

440. *Rudolph A, Milne R, Truong T, Knight J, Seibold P, Flesch-Janys D, ..., Lissowska J, Sherman M, Brüning T, Hamann U, Ko Y, Orr N, Schoemaker M, ...Garcia-Closas M, Chang-Claude J. Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility. Int J Cancer 2015; 136: E685-96 IF: 6.400

439. *Lin WY, Ghoussaini M, Beesley J, Michailidou K, Hopper J, APicella C,... Brauch H, Brüning T, Ko Y, Tessier D, Vincent D, ..., Dünning A, Easton DF, Cox A
Identification and characterisation of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Hum Mol Genet 2015; 24: 285-298 IF: 3.500

438. *Pesch B, Lotz A, Koch HM, Marczynski B, Casjens S, Käfferlein HU, Welge P, Lehnert M, Heinze E, Van Gelder R, Hahn JU, Behrens T, Raulf M, Hartwig A, Weiß T, Brüning T. Oxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores. Arch Toxicol 2015; 89: 1257-1269 IF: 6.100

437. *Consonni D, De Matteis S, Pesatori AC, Bertazzi PA, Olsson AC, Kromhout H, Peters S, Vermeulen RC, Pesch B, Brüning T, Kendzia B, Behrens T, Stücker I, Guida F, Wichmann HE, Brüske I, Landi MT, Caporaso NE, Gustavsson P, Plato N, Tse LA, Yu IT, Jöckel KH, Ahrens W, Pohlabeln H, Merletti F, Richiardi L, Simonato L, Forastiere F, Siemiatycki J, Parent ME, Tardón A, Boffetta P, Zaridze D, Chen Y, Field JK, 't Mannetje A, Pearce N, McLaughlin J, Demers P, Lissowska J, Szeszenia-Dabrowska N, Bencko V, Foretova L, Janout V, Rudnai P, Fabiánová E, Stanescu Dumitru R, Bueno-de-Mesquita B, Schüz J, Straif K. Lung cancer risk among bricklayers in a pooled analysis of case-control studies. Int J Cancer 2015; 136: 360-371 IF: 6.400

436. *Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, ..., Brauch H, Brüning T, Ko YD, GENICA Network, Brenner H, ..., Chenevix-Trench G, Blomqvist C, Aittomäki K, Easton DF, Nevanlinna H. MicroRNA Related Polymorphisms and Breast Cancer Risk. PLoS One 2014; 9: e109973 IF: 3.700

435. *Hoffmeyer F, van Kampen V, Taeger D, Deckert A, Rosenkranz N, Kaßen M, Schantora AL, Brüning T, Raulf M, Bünger J. Prevalence of and relationship between rhinoconjunctivitis and lower airway diseases in compost workers with current or former exposure to organic dust. Ann Agric Environ Med 2014; 21: 705-711 IF: 1.700

434. *Weber DG, Casjens S, Johnen G, Bryk O, Raiko I, Pesch B, Kollmeier J, Bauer TT, Brüning T. Combination of MiR-103a-3p and mesothelin improves the biomarker performance of malignant mesothelioma diagnosis. Plos One 2014; 9: e114483 IF: 3.700

433. *Bonberg N, Pesch B, Behrens T, Johnen G, Taeger D, Gawrych K, Schwentner C, Wellhäußer H, Kluckert M, Leng G, Nasterlack M, Oberlinner C, Stenzl A, Brüning T. Chromosomal alterations in exfoliated urothelial cells from bladder cancer cases and healthy men: a prospective screening study. BMC Cancer 2014; 14: 854 IF: 3.800

432. *Koslitz S, Meier S, Schindler BK, Weiß T, Koch HM, Brüning T, Käfferlein HU. Biomonitoring of N-ethyl-2-pyrrolidone in automobile varnishers. Tox Lett 2014; 231: 142-146 IF: 3.500

431. *Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE, Nordestgaard BG,... Brauch H, Brüning T, Koto YD, Radice P, Peterlongo P, Bonanni B, ..., Bacot F, de Santiago I, Carroll J, Caldas C, Brown MA, Lupien M, Kristensen VN, Pharoah PD, Chenevix-Trench G, French JD, Easton DF, Dunning AM. Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nat Commun 2014; 4: 4999 IF: 16.600

430. *Rabstein S, Harth V, Justenhoven C, Pesch B, Plöttner S, Heinze E, Lotz A, Baisch C, Schiffermann M, Brauch H, Hamann U, Ko Y, Brüning T, on behalf of the GENICA Consortium Polymorphisms in circadian genes, night work and breast cancer: Results from the GENICA study. Chronobiol Int. 2014; 31: 1115-1122 IF: 2.800

429. *Casjens S, Henry J, Rihs HP, Lehnert M, Raulf M, Welge P, Lotz A, Van Gelder R, Hahn JU, Stiegler H, Eisele L, Weiß T, Hartwig A, Brüning T, Pesch B. Influence of welding fume on systemic iron status. Ann Occup Hygiene 2014; 58: 1143-1154 IF: 2.241

428. *Brüning T, Bartsch R, Bolt HM, Desel H, Drexler H, Gundert-Remy U, Hartwig A, Jäckh R, Leibold E, Pallapies D, Rettenmeier AW, Schlüter G, Stropp G, Sucker K, Triebig G, Westphal GA, van Thriel C. Sensory irritation as a basis for setting occupational exposure limits. Arch Toxicol 2014; 88:1855-1879 IF: 6.100

427. *Rihs HP, Armentia A, Sander I, Brüning T, Raulf M, Varga R. IgE-binding properties of a recombinant lipid transfer protein from Cannabis sativa. Ann Allergy Asthma Immunol 2014; 113: 233-234 IF: 5.900

426. *Moos RK, Angerer J, Wittsiepe J, Wilhelm M, Brüning T, Koch HM. Rapid determination of nine parabens and seven other environmental phenols in urine samples of German children and adults. Int J Hyg Environ Health 2014; 217: 845-853 IF: 6.000

425. *Denholm R, Schüz J, Straif K, Stücker I, Jöckel KH, Brenner DR, De Matteis S, Boffetta P, Guida F, Brüske I, Wichmann HE, Landi MT, Caporaso N, Siemiatycki J, Ahrens W, Pohlabeln H, Zaridze D, Field JK, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Dumitru RS, Bencko V, Foretova L, Janout V, Kendzia B, Peters S, Behrens T, Vermeulen R, Brüning T, Kromhout H, Olsson A. Is Previous Respiratory Disease a Risk Factor for Lung Cancer? Am J Crit Care Med 2014; 190: 549-559 IF: 2.700

424. *Darwiche K, Ozkan F, Ting S, Johnen G, Brüning T, Soltermann A, Huber LC, Christoph DC, Freitag L, Franzen D. Role of pretherapeutic biomarkers in lung cancer with special regards to bronchoscopic procedures. Pneumologie 2014; 68: 719-726 IF: 1.200

423. *Leng G, Koch HM, Gries W, Schütze A, Langsch A, Brüning T, Otter R. Urinary metabolite excretion after oral dosage of bis(2-propylheptyl)phthalate (DPHP) to five male volunteers – characterization of suitable biomarkers for human biomonitoring. Toxicol Lett 2014; 231: 282-288 IF: 3.500

422. *Kasper-Sonnenberg M, Koch HM, Wittsiepe J, Brüning T, Wilhelm M. Phthalate metabolites and bisphenol A in urines from German school-aged children: Results of the Duisburg Birth Cohort and Bochum Cohort Studies. Int J Hyg Environ Health 2014; 217: 830-838 IF: 6.000

421. *Behrens T, Stenzl A, Brüning T. Factors Influencing false-positive results for nuclear matrix protein 22. Eur Urol 2014; 66: 970-972 IF: 23.400

420. *Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H..., The GENICA Network, Brüning T, Ko YD, van Deurzen CH,...Slager S, Vachon CM, Couch FJ. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. Hum Mol Genet 2014; 15: 6034-6046 IF: 3.500

419. *Käfferlein HU, Broding HC, Bünger J, Jettkant B, Koslitz S, Lehnert M, Marek EM, Blaszkewicz M, Monsé C, Weiß T, Brüning T. Human exposure to airborne aniline and formation of methemoglobin: a contribution to occupational exposure limits. Arch Toxicol 2014; 88: 1419-1426 IF: 6.100

418. *Monsé C, Bünger J, Brüning T, Merget R. Generation and characterization of airborne ethyl-2-cyanoacrylate atmospheres in a human whole-body exposure unit. Anal Methods 2014; 6: 3124 IF: 3.100

417. *Monsé C, Broding HC, Sucker K, Berresheim H, Jettkant B, Hoffmeyer F, Merget R, Brüning T, Bünger J. Exposure assessment of potash miners at elevated CO2 levels. Int Arch Occup Env Health 2014; 87:413-421 IF: 3.000

416. *Lehnert M, Weiß T, Pesch B, Lotz A, Zilch-Schöneweis S, Heinze E, Van Gelder R, Hahn JU, Brüning T, The WELDOX Study Group. Reduction in welding fume and metal exposure of stainless steel welders: an example from the WELDOX study. Int Arch Occup Env Health 2014; 87: 483-492 IF: 3.000

415. *Köhler CU, Martin L, Bonberg N, Behrens T, Deix T, Braun K, Noldus J, Jöckel KH, Erbel R, Sommerer F, Tannapfel A, Harth V, Käfferlein HU, Brüning T. Automated quantification of FISH signals in urinary cells enables the assessment of chromosomal aberration patterns characteristic for bladder cancer. Biochem Biophys Res Commun 2014; 9: e114483 IF: 3.100

414. *Kampen van V, Sander I, Liebers V, Deckert A, Neumann HD, Buxtrup M, Willer E, Felten C, Jäckel U, Klug K, Brüning T, Raulf M, Bünger J. Concentration of bioaerosols in composting plants using different quantification methods. Ann Occup Hyg 2014; 58: 693-706 IF: 2.241

413. *Raulf M, Sander I, Gonnissen D, Zahradnik E, Brüning T. Schaben und Co. Die Rolle von Gesundheitschädlingen als Allergenquelle. Bundesgesundheitsbl 2014; 57: 585-592 IF: 1.700

412. *Taeger D, Hagemeyer O, Merget R, Brüning T, Pallapies D. Is there a lung cancer risk in US coal miners? Occup Environ Med 2014; 71: 523 IF: 4.900

411. *Schütze A, Kolossa-Gehring M, Apel P, Brüning T, Koch HM. Entering markets and bodies: Increasing levels of the novel plasticizer Hexamoll® DINCH® in 24h urine samples from the German Environmental Specimen Bank. Int J Hyg Env Health 2014; 217: 421-426 IF: 6.000

410. *Vossoughi M, Schikowski T, Vierkötter A, Sugiri D, Hoffmann B, Teichert T, Herder C, Schulte T, Luckhaus C, Raulf-Heimsoth M, Casjens S, Brüning T, Krämer U. Air pollution and subclinical airway inflammation in the SALIA cohort study. Immun Ageing 2014; 11: 5 IF: 7.900

409. *Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT,... Brauch H, Brüning T, Hamann U, The GENICA Network, Dunning AM, ..., Bogdanova N, Dörk T, Hall P, Chenevix-Trench G, Easton DF, Pharoah PDP, Arias-Perez JI, Zamora P, Benitez J, Milne RL. FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. Br J Cancer 2014; 110: 1088-1100 IF: 8.800

408. *Seidler A, Brüning T, Taeger D, Möhner M, Gawrych K, Bergmann A, Haerting J, Bolt HM, Straif K, Harth V. Cancer incidence among workers occupationally exposed to dinitrotoluene in the copper mining industry. Int Arch Occup Env Health 2014; 87: 117-124 IF: 3.000

407. *Monsé C, Monz C, Dahmann D, Asbach C, Stahlmecke B, Buchwald KE, Merget R, Bünger J, Brüning T. Development and evaluation of a nanoparticle generator for human inhalation studies with airborne zinc oxide. Aerosol Sci Technol 2014; 48: 418-426 IF: 5.200

406. *Seidler A, Harth V, Taeger D, Mohner M, Gawrych K, Bergmann A, Haerting J, Kahmann HJ, Bolt HM, Brüning T. Dinitrotoluene exposure in the copper mining industry and renal cancer: a case-cohort study. Occup Env Med 2014; 71: 259-265 IF: 4.900

405. *Modick H, Weiß T, Dierkes G, Brüning T, Koch HM. Ubiquitous presence of paracetamol in human urine: sources and implications. Reproduction 2014; 147: 105-117 IF: 3.800

404. *Ollesch J, Heinze M, Heise HM, Behrens T, Brüning T, Gerwert K. It's in your blood: spectral biomarker candidates for urinary bladder cancer from automated FTIR spectroscopy. J Biophotonics 2014; 7: 210-221 IF: 2.800

403. *Justenhoven C, Pentimalli D, Rabstein S, Harth V, Lotz A, Pesch B, Brüning T, Dörk T, Schürmann P, Bogdanova N, Park-Simon TW, Couch FJ, Olson JE, Fasching PA, Beckmann MW, Häberle L, Ekici A, Hall P, Czene K, Liu J, Li J, Baisch C, Hamann U, Ko YD, Brauch H. CYP2B6*6 is associated with increased breast cancer risk. Int J Cancer 2014; 134: 426-430 IF: 6.400

402. *Schindler BK, Koslitz S, Weiss T, Broding HC, Brüning T, Bünger J. Exposure of aircraft maintenance technicians to organophosphates from hydraulic fluids and turbine oils: A pilot study. Int J Hyg Environ Health 2014; 217: 34-37 IF: 6.000

401. *Westphal GA, Tüshaus C, Monse C, Rosenkranz N, Brüning T, Bünger J. Amylenes do not lead to bacterial mutagenicity in contrast to structurally related epoxides. BioMed Research International 2014; 1-5 doi: 10.1155/2014/592434 IF: 3.246

400. *Pesch B, Brüning T, Johnen G, Casjens S, Bonberg N, Taeger D, Müller A, Weber DG, Behrens T. Biomarker research with prospective study designs for the early detection of cancer. BBA-Proteins Proteomics 2014; 1844: 874-883 IF: 3.200

399. *Vlaanderen J, Portengen L, Schütz J, Olsson A, Pesch B, Kendzia B, Stücker I, Guida F, Brüske I, Wichmann HE, Conconni D, Landi MT, Caporaso N, Siemiatycki J, Merletti F, Mirabelli D, Richiardi L, Gustavsson P, Plato N, Jöckel KH, Ahrens W, Pohlabeln H, Tardon A, Zaridze D, Field JK, t'Mannetje A, Pearce N, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, ...Bofetta P, Forstiere F, Bueno-de-Mesquita B, Peters S, Brüning T, Kromhout H, Straif K, Vermeulen R. Effect Modification of the Association of Cumulative Exposure and Cancer Risk by Intensity of Exposure and Time Since Exposure Cessation: A Flexible Method Applied to Cigarette Smoking and Lung Cancer in the SYNERGY Study. Am J Epidemiol 2014; 179: 290-298 IF: 5.000

398. *Milne R, Herranz J, Michailidou K, Dennis J, Tyrer J, Zamora M, Arias-Perez J, González-Neira A, Pita G, Alonso M, Wang Q, Bolla M, Czene K, … ,Børresen-Dale A-L, García-Closas M, Chanock S J, Lissowska J, Figueroa JD,Schmidt MK, Broeks A, Verhoef S, Rutgers EJ, Brauch H, Brüning T, Ko Y-D, Couch F J, Toland AE, Yannoukakos D, Pharoah Paul DP, Hall P, Benítez J, Malats N, Easton F. A Large-Scale Assessment of Two-Way SNP Interactions in Breast Cancer Susceptibility Using 46,450 Cases and 42,461 Controls from the Breast Cancer Association Consortium. Hum Mol Genet 2014; 23: 1934-1946 IF: 3.500

397. *Koch HM, Bader M, Weiß T, Koslitz S, Schütze A, Käfferlein HU, Brüning T. Metabolism and elimination of N-ethyl-2-pyrrolidone (NEP) in human males after oral dosage.
Arch Tox 2014;88: 893-899 IF: 6.100

396. *Pesch B, Taeger D, Johnen G, Gawrych K, Bonberg N, Schwentner C, Wellhäußer H, Kluckert M, Leng G, Nasterlack M, Lotan Y, Stenzl A, Brüning T, the UroScreen Study Group. Screening for bladder cancer with urinary tumor markers in chemical workers with exposure to aromatic amines. Int Arch Occup Environ Health 2014; 87: 712-724 IF: 3.000

395. *Westphal GA, Krahl J, Munack A, Rosenkranz N, Schr&oumL,der O, Schaak J, Pabst C, Brüning T, Bünger J. Combustion of hydrotreated vegetable oil and jatropha methyl ester in a heavy duty engine: emissions and bacterial mutagenicity. Environ Sci Technol. 2013 Jun 4;47: 6038-6046 IF: 11.400

394. *Dierkes G, Weiß T, Modick H, Käfferlein HU, Brüning T, Koch HM. N-Acetyl-4-aminophenol (paracetamol), N-acetyl-2-aminophenol and acetanilide in urine samples from the general population, individuals exposed to aniline and paracetamol users.
Int J Hyg Environ Health 2013; 217: 592-599 IF: 6.000

393. *Raulf-Heimsoth M, Liebig R, Marczynski B, Borowitzki G, Bernard S, Freundt S, Heinze E, Brüning T, Merget R. Implementation of non-invasive methods in the diagnosis of diisocyanate-induced asthma. Adv Exp Med Biol 2013; 788: 293-300 IF: 3.650

392. *Ewald-Kleimeier S, Lotz A, Merget R, Brüning T, Hagemeyer O. Exhaled nitric oxide in specific inhalation challenge. Adv Exp Med Biol 2013; 788: 255-264 IF: 3.650

391. *Hagemeyer O, Bünger J, van Kampen V, Raulf-Heimsoth M, Drath C, Merget R, Brüning T, Broding HC. Occupational allergic respiratory diseases in garbage workers: relevance of molds and actinomycetes. Adv Exp Med Biol 2013; 788: 313-320 IF: 3.650

390. *Scheidler L, Sucker K, Taeger D, van Kampen V, Heinze E, Marczynski B, Monsé C, Brüning T, Merget R. Evaluation of a 4-steps-1-day whole body challenge protocol for the diagnosis of occupational asthma due to diisocyanates. Adv Exp Med Biol 2013; 788: 301-311 IF: 3.650

389. *Merget R, Sander I, van Kampen V, Raulf-Heimsoth M, Rabente T, Kolk A, Brüning T. Hypersensitivity pneumonitis due to metalworking fluids: how to find the antigens. Adv Exp Med Biol 2013; 788: 335-40 IF: 3.650

388. *Punsmann S, Liebers V, Lotz A, Brüning T, Raulf M.Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. PLoS One 2013; 8(12):e82734 IF: 3.700

387. *Weber DG, Johnen G, Casjens S, Bryk O, Pesch B, Jöckel KH, Kollmeier J, Brüning T. Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer. BMC Research Notes 2013; 6: 518 IF: 1.800

386. *Meyer KB, O'Reilly M, Michailidou K, Carlebur S, ..., Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Schmutzler RK, Engel C, Ditsch N, Brauch H, Brüning T, Ko YD; The GENICA Network, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Yatabe Y, Dörk T, Helbig S, Bogdanova NV, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, ..., Ashworth A, Orr N, Schoemaker MJ, Ponder BA, Dunning AM, Easton DF. Fine-Scale mapping of the FGFR2 breast cancer risk Locus: Putative functional variants differentially Bind FOXA1 and E2F1. Am J Hum Genet 2013; 93: 1046-1060 IF: 9.800

385. *Ahrens M, Turewicz M, Casjens S, May C, Pesch B, Stephan C, Woitalla D, Gold R, Brüning T, Meyer HE, Rahnenführer J, Eisenacher M. Detection of patient subgroups with differential expression in omics data: a comprehensive comparison of univariate measures. PLoS One 2013; 8(11): e79380 IF: 3.700

384. *Rudolph A, Hein R, Lindström S, Beckmann L, Behrens S, Liu J, Aschard H, Bolla MK, Wang J, Truong T, Cordina-Duverger E, Menegaux F, Brüning T, Harth V, Genica Network T, Severi G, Baglietto L, Southey M, Chanock SJ, Lissowska J, Figueroa JD, Eriksson M, Humphreys K, Darabi H, Olson JE, Stevens KN, Vachon CM, Knight J, Glendon G, Mulligan AM, Ashworth A, Orr N, Schoemaker M, Webb PM, Investigators K, Management Group A, Guénel P, Brauch H, Giles G, Garcia-Closas M, Czene K, Chenevix-Trench G, Couch FJ, Andrulis IL, Swerdlow A, Hunter DJ, Flesch-Janys D, Easton DF, Hall P, Nevanlinna H, Kraft P, Chang-Claude J. Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study. Endocr Relat Cancer 2013; 20: 875-887 IF: 3.900

383. *Kespohl S, Maryska S, Zahradnik E, Sander I, Brüning T, Raulf-Heimsoth M. Biochemical and immunological analysis of mould skin prick test solution: current status of standardization. Clin Exp Allergy 2013;43: 1286-1296 IF: 6.100

382. *Pesch B, Gawrych K, Rabstein S, Weiß T, Casjens S, Rihs HP, Ding H, Angerer J, Illig T, Klopp N, Bueno-de-Mesquita HB, Ros MM, Kaaks R, ..., Brüning T, Vineis P. NAT2 acetylator phenotype, occupation and bladder cancer risk: Results from the EPIC cohort. Cancer Epidemiol Biomarkers Prev 2013; 22: 2055-2065 IF: 3.800

381. *Kendzia B, Behrens T, Jockel K, Siemiatycki J, Kromhout H, Vermeulen R, Peters S, van Gelder R, Olsson A, Brüske I, Wichmann H, Stucker I, Guida F, Tardon A, Merletti F, Mirabelli D, Richiardi L, Pohlabeln H, Ahrens W, Landi M, Caporaso N, Consonni D, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Gustavsson P, Marcus M, Fabianova E, Mannetje A 't, Pearce N, Tse L, Yu I, Rudnai P, Bencko V, Janout V, Mates D, Foretova L, Forastiere F, McLaughlin J, Demers P, Bueno-de-Mesquita B, Boffetta P, Schüz J, Straif K, Pesch B, Brüning T. Welding and Lung Cancer in a Pooled Analysis of Case-Control Studies. Am J Epidemiol 2013; 15: 1513-1525 IF: 5.000

380. *Olsson A, Xu Y, Schüz J, Vlaanderen J, Kromhout H, Vermeulen R, Peters S, Stücker I, Guida F, Brüske I, Wichmann HE, Consonni D, Landi MT, Caporaso N, Ah Tse L, Yu IT, Siemiatycki J, Richardson L, Mirabelli D, Richiardi L, Simonato L, Gustavsson P, Plato N, Jöckel KH, Ahrens W, Pohlabeln H, Tardon A, Zaridze D, Marcus MW, t'Mannetje A, Pearce N, McLaughlin J, Demers P, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Dumitru RS, Bencko V, Foretova L, Janout V, Bofetta P, Fortes C, Bueno-de-Mesquita B, Kendzia B, Behrens T, Pesch B, Brüning T, Straif K. Lung Cancer Risk Among Hairdressers: A Pooled Analysis of Case-Control Studies Conducted Between 1985 and 2010. Am J Epidemiol 2013; 178: 1355-1365 IF: 5.000

379. *Behrens T, Bonberg N, Casjens S, Pesch B, Brüning T. A practical guide to epidemiological practice and standards in the identification and validation of diagnostic markers using a bladder cancer example. BBA-Proteins and Proteomics 2013; 1844: 145-155 IF: 3.200

378. *Köhler CU, Bryk O, Meier S, Lang K, Rozynek P, Brüning T, Käfferlein HU. Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers. Biochem Biophys Res Commun. 2013; 438: 48-53. IF: 3.100

377. *Behrens T, Kendzia B, Treppmann T, Olsson A, Jöckel KH, Gustavsson P, Pohlabeln H, Ahrens W, Brüske I, Wichmann HE, Merletti F, Mirabelli D, Richiardi L, Simonato L, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, ..., Plato N, Boffetta P, Straif K, Schüz J, Pesch B, Brüning T. Lung cancer risk among bakers, pastry cooks and confectionary makers: the SYNERGY study. Occup Environ Med 2013; 70: 810-814 IF: 4.900

376. *Hoffmeyer F, Sucker K, Monsé C, Berresheim H, Rosenkranz N, Jettkant B, Beine A, Brüning T, Bünger J. Relationship of pulmonary function response to ozone exposure and capsaicin cough sensitivity. Inhal Toxicol 2013; 25: 569-76. IF: 2.100

375. *Plöttner S, Käfferlein HU, Brüning T. Miniaturization of cytotoxicity tests for concentration range-finding studies prior to conducting the pH 6.7 Syrian hamster embryo cell-transformation assay. Mutat Res Genet Toxicol Environ Mutagen 2013; 755: 108-14 IF: 1.900

374. *Pallapies D, Taeger D, Hagemeyer O, Merget R, Brüning T. Clinically significant lung function impairment due to current levels of respirable quartz? Occup Environ Med 2013; 70: 893 IF: 4.900

373. *Justenhoven C, Obazee O, Winter S, Rabstein S, Lotz A, Harth V, Pesch B, Brüning T, Baisch C, Hartikainen JM, Mannermaa A, Kosma VM, Kataja V, Winqvist R, Pylkes K, Jukkola-Vuorinen A, Grip M, Fasching P, Beckmann M, Ekici AB, Hein A, Hall P, Li J, Chang-Cluade J, Flesch-Janys D, Seibold P, Rudolph A, Hamann U, Ko YD, Brauch H. The UGT1A6_19_GG genotype is a breast cancer risk factor. Front Pharmacogenetics Pharmocogenomics 2013; 4: 104

372. *Sander I, Zahradnik E, Kraus S, Mayer H, Neumann H, Fleischer C, Brüning T, Raulf-Heimsoth M. Neues Messverfahren zum Nachweis von Hausmilbenantigenen auch in Luftstaubproben aus Innenräumen von Wohnungen und Arbeitsplätzen. Gefahrstoffe Reinhalt Luft 2013; 73: 281-284 IF: 0.300

371. *Pesch B, Weiß T, Pallapies D, Schlüter G, Brüning T. Re: Seidler A, Jänichen S, Hegewald J et al. Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent chromium FTIR spectroscopy of biofluids revisited: an automated approach to spectral biomarker identification. Int Arch Occup Env Health 2013; 86: 957-960 IF: 3.000

370. *Ollesch J, Drees SL, Heise HM, Behrens T, Brüning T, Gerwert K. FTIR spectroscopy of biofluids revisited: an automated approach to spectral biomarker identification. Analyst 2013; 138: 4092-4102 IF: 4.200

369. *Bonberg N, Taeger D, Gawrych K, Johnen G, Banek S, Schwentner C, Sievert K, Wellhäußer H, Kluckert M, Leng G, Nasterlack M, Stenzl A, Behrens T, Brüning T, Pesch B. Chromosomal instability and bladder cancer: the UroVysion(TM) test in the UroScreen study. BJU Int 2013; 112: 372-82 IF: 4.500

368. *Zahradnik E, Kespohl S, Sander I, Schies U, Khosravie-Hohn J, Lorenz W, Engelhart S, Kolk A, Schneider G, Brüning T, Raulf-Heimsoth M. A new immunoassay to quantify fungal antigens from the indoor mould Aspergillus versicolor. Environ Sci Process Impacts 2013; 15: 1162-71 IF: 5.500

367. *Casjens S, Eckert A, Woitalla D, Ellrichmann G, Turewicz M, Stephan C, Eisenacher M, May C, Meyer HE, Brüning T, Pesch B. Diagnostic value of the impairment of olfaction in Parkinson's disease. PLoS One 2013; 8: e64735 IF: 3.700

366. *Johnen G, Rozynek P, von der Gathen Y, Bryk O, Zdrenka R, Johannes C, Weber DG, Igwilo-Okuefuna OB, Raiko I, Hippler J, Brüning T, Dopp E. Cross-Contamination of a UROtsa Stock with T24 Cells - Molecular Comparison of Different Cell Lines and Stocks. PLoS One 2013; 8: e64139 IF: 3.700

365. *Hein R, Flesch-Janys D, Dahmen N, Beckmann L, Lindström S, Schoof N, Czene K, Mittelstrat K, Illig T, Seibold P, Behrens S, Humphreys K, Li J, Liu J, Olson J, Wang X, Hankinson S, Truong T, Menegaux F, dos Santos Silva I, Johnson N, Chen S, Yu J, Ziogas A, Kataja V, Kosma V, Mannermaa A, Anton-Culver H, Shen C, Brauch H, Peto J, Guanel P, Kraft P, Couch F, Easton D, GENICA Network, Hall P, Chang-Claude J. A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication. Breast Cancer Res Tr 2013; 138: 529-542 IF: 3.800

364. *Turewicz M, May C, Ahrens M, Woitalla D, Gold R, Casjens S, Pesch B, Brüning T, Meyer HE, Nordhoff E, Böckmann M, Stephan C, Eisenacher MD. Improving the default data analysis workflow for large autoimmune biomarker discovery studies with protoarrays. Proteomics 2013; 13: 2083-7 IF: 3.400

363. *Taeger D, Pallapies D, Brüning T. Qualitative job-exposure-matrix -- a tool for the quantification of population-attributable fractions. Int J Epidemiol 2013; 42: 356-357 IF: 7.700

362. *Nickels S, Truong T, Hein R, Stevens K, Buck, Behrens S, ..., Brauch H, Brüning T, Harth V, The Genica Network,..., Paridaens R, Flesch-Janys D, Obi N, Wang-Gohrke S,..., Pharoah PD, Schmidt MK, Hall P, Easton DF, Garcia-Closas M, Milne RL, Chang-Claude J. Evidence of Gene-Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors. PLoS Genet 2013 9:e1003284 IF: 4.500

361. *Rabstein S, Harth V, Pesch B, Pallapies D, Lotz A, Justenhoven C, Baisch C, Schiffermann M, Haas S, Fischer HP, Heinze E, Pierl C, Brauch H, Hamann U, Ko Y, Brüning T. Night work and breast cancer estrogen receptor status - results from the German GENICA study. Scand J Work Environ Health 2013; 39: 448-455 IF: 6.300

360. *Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K,..., Brauch H, Chang-Claude J, Carpenter J, Godwin AK,..., Guénel P, Burwinkel B, Sawye EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A,..., Justenhoven C, Ko Y, Gene Environmental Interaction and breast CAncer (GENICA) Network,..., Familial Breast Cancer Study (FBCS), Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Auststralian Breast Cancer Tissue Bank (ABCTB) Investigators,..., Brüning T, ..., Pharoah PD, Vachon C, Easton DF, Haiman CA, Kraft P. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 2013; 45: 392-398 IF: 30.800

359. *Bojesen SE, Pooley KA,..., Australian Cancer Study Australian Ovarian Cancer Study Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) Gene Environment Interaction and Breast Cancer (GENICA) Swedish Breast Cancer Study (SWE-BRCA) Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE), Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO),..., Hamann U, Karlan BY,..., Brüning T, Pike MC, Ko Y,..., Schmutzler RK, Ito H,..., Pharoah PD, Reddel RR, Goode EL, Greene MH, Easton DF, Berchuck A, Antoniou AC, Chenevix-Trench G, Dunning AM. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet 2013; 45:371-384 IF: 30.800

358. * Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M,..., Chang-Claude J, Bojesen SE, Bolla MK, Wang Q,..., Breast and Ovarian Cancer Susceptibility Collaboration,..., Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON),..., kConFab Investigators,..., Australian Ovarian Cancer Study Group,..., Brauch H, Hamann U, Brüning T, GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network,..., Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zhen, W, ..., Benitez J, Easton DF. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013; 45: 353-361 IF: 30.800

357. *Modick H, Schütze A, Pälmke C, Weiß T, Brüning T, Koch HM. Rapid determination of N-acetyl-4-aminophenol (paracetamol) in urine by tandem mass spectrometry coupled with on-line clean-up by two dimensional turbulent flow/reversed phase liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2013; 15: 33-9 IF: 1.911

356. *van Kampen V, Lessmann H, Brüning T, Merget R. Occupational allergies against pepsin, chymosin and microbial rennet. Pneumologie 2013; 67: 260-264 IF: 1.200

355. *van Kampen V, Blay F, Folletti I, Kobierski P, Moscato G, Olivieri M, Quirce S, Sastre J, Walusiak-Skorupa J, Kotschy-Lang N, Müsken H, Mahler V, Schliemann S, Ochmann U, Schültz J, Worm M, Sander I, Zahradnik E, Brüning T, Merget R, Raulf-Heimsoth M. Evaluation of commercial skin prick test solutions for selected occupational allergens. Allergy 2013; 68: 651-658 IF: 12.400

354. *Weiß T, Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T. Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Arch Toxicol 2013; 87: 1265-1272 IF: 6.100

353. *Meier S, Schindler BK, Koslitz S, Koch HM, Weiß T, Käfferlein HU, Brüning T. Biomonitoring of Exposure to N-Methyl-2-Pyrrolidone in workers of the automobile industry. Ann Occup Hyg 2013; 57: 766-73 IF: 2.241

352. *Weiß T, Pesch B, Lotz A, Gutwinski E, Van Gelde R, Punkenburg E, Kendzia B, Gawrych K, Lehnert M, Heinze E, Hartwig A, Käfferlein HU, Hahn JU, Brüning T, the WELDOX Group. Levels and predictors of airborne and internal exposure to chromium and nickel among welders-Results of the WELDOX study. Int J Environ Health 2013; 216: 175-183 IF: 3.200

351. *Obazee O, Justenhoven C, Winter C, Chang-Claude J, Rudolph A, Flesch-Jannys D, Rabstein S, Harth V, Lotz A, Pesch B, Brüning T, Baisch C, Ko Y, Hamann U, Brauch H. Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant. Breast Cancer Res Tr 2013; 138: 543-548 IF: 3.800

350. *Peters S, Kromhout H, Portengen L, Olsson A, Kendzia B, Vincent R, Savary B, Lavoué J, Cavallo D, Cattaneo A, Mirabelli D, Plato N, Fevotte J, Pesch B, Brüning T, Straif K, Vermeulen R. Sensitivity analyses of exposure estimates from a quantitative job-exposure matrix (SYN-JEM) for use in community-based studies. Ann Occup Hyg 2013; 57:98-106 IF: 2.241

349. *Bermejo JL, Kabisch M, Dünnebier T, Schmaidt S, Melchior F, Fischer H, P, Harth V, Rabstein S, Pesch B, Brüning T, Justenhoven C, Brauch H, Baisch C, Ko Y, Hamann U
Exploring the association between inherited variation in the ubiquitin-specific peptidase-like 1 gene (USPL1) and breast cancer through integration of data from the population-based GENICA study and external genetic databases. Int J Cancer 2013; 133: 362-372 IF: 6.400

348. *Koch HM, Christensen M, Lorber C, Pälmke C, Koslitz S, Brüning T. Identifying sources of phthalate exposure with human biomonitoring: results of a 48 hour fasting study with urine collection and personal activity patterns. Int J Hyg Env Health 2013; 216: 672-681 IF: 6.000

347. *Schindler BK, Weiß T, Schütze A, Koslitz S, Broding HC, Bünger J, Brüning T. Occupational exposure of air crews to tricresyl phosphate isomers and organophosphate flame retardants after fume events. Arch Toxicol 2013; 87: 645-8 IF: 6.100

346. *Koch H, Schütze A, Pälmke C, Angerer J, Brüning T. Metabolism of the plasticizer and phthalate substitute diisononyl-cyclohexane-1,2-dicarboxylate (DINCH(®)) in humans after single oral doses. Arch Toxicol 2013; 87: 799-806 IF: 6.100

345. *Banek S, Schwentner C, Taeger D, Pesch B, Nasterlack M, Leng G, Gawrych K, Bonberg N, Kluckert M, Gakis G, Todenhöfer T, Hennenlotter J, Brüning T, Stenzl A, UroScreen Study Group. Prospective evaluation of fluorescence-in situ-hybridization to detect bladder cancer: Results from the UroScreen-Study. Urol Oncol 2013; 31: 1656-1662 IF: 0.818

344. *Punsmann S, Liebers V, Stubel H, Brüning T, Raulf-Heimsoth M. Determination of inflammatory responses to Aspergillus versicolor and endotoxin with human cryo-preserved blood as a suitable tool. Int J Hyg Env Health 2012; 26: ppi: S1438-4639 IF: 6.000

343. *Sander I, Zahradnik E, Kraus G, Mayer S, Neumann HD, Fleischer C, Brüning T, Raulf-Heimsoth M. Domestic Mite Antigens in Floor and Airborne Dust at Workplaces in Comparison to Living Areas: A New Immunoassay to Assess Personal Airborne Allergen Exposure. PLoS One 2012; 7: e52981 IF: 3.700

342. *Hein R, Maranian M, Hopper JL, The GENICA Network, Easton DF, Dunning AM. Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS One 2012; 7:e42380 IF: 3.700

341. *Pesch B, Casjens S, Stricker I, Westerwick D, Taeger D, Rabstein S, Wiethege T, Tannapfel A, Brüning T, Johnen G. NOTCH1, HIF1A and Other Cancer Related Proteins in Lung Tissue from Uranium Miners-Variation by Occupational Exposure and Subtype of Lung Cancer. PLoS One 2012; 7: e45305 IF: 3.700

340. *Sander I, Zahradnik E, van Kampen V, Kespohl S, Stubel H, Fischer G, Brüning T, Bünger J, Raulf-Heimsoth M. Development and application of mold antigen-specific enzyme-linked immunosorbent assays (ELISA) to quantify airborne antigen exposure. J Toxicol Env Health A 2012; 75: 1185-93 IF: 1.036

339. *Fartasch M, Wittlich M, Broding HC, Gellert B, Blome H, Brüning T. [Skin and occupational artificial UV-radiation. Hautarzt 2012; 63: 788-795 IF: 1.198

338. *Christensen KL, Lorber M, Koslitz S, Brüning T, Koch HM. The contribution of diet to total bisphenol A body burden in humans: Results of a 48hour fasting study. Environ Int 2012; 50: 7-14 IF: 11.800

337. *Sogl M, Taeger D, Pallapies P, Brüning T, Dufey F, Schnelzer M, Straif K, Walsh L, Kreuzer M. Quantitative relationship between silica exposure and lung cancer mortality in German uranium miners 1946-2003. Br J Cancer 2012; 107: 1188-1194 IF: 8.800

336. *Kirchhoff T, Gaudet M, M, GENICA-Network, Chenevix-Trench G, Easton DF. Breast Cancer Risk and 6q22, 33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2. Plos One 2012 7(6): e35706 IF: 3.700

335. *Liebers V, Brinkert S, Brüning T, Raulf-Heimsoth M. Bioaerosole - mehr als nur Allergene: komplexe Situationen an Arbeitsplätzen. Allergologie 2012; 35 8: 413-424 IF: 0.500

334. *Warren H, Durbridge F, Fletcher H, Brüning T, Peto J, dos Santos-Silva I.
9q31, 2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium. Cancer Epidem Biomark & Prev 2012; 21: 1783-1791 IF: 3.800

333. *Koch HM, Christensen KL, Harth V, Lorber M, Brüning T. Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses.
Arch Toxicol 2012; 86: 1829-1839 IF: 6.100

332. Raulf-Heimsoth M, Kespohl S, van Kampen V, Sander I, Zahradnik E, Brüning T. Inhalationsallergien am Arbeitsplatz. Allergologie 2012; 35: 274-285 IF: 0.500

331. Raulf-Heimsoth M, Zahradnik E, Sander I, Fleischer C, Kespohl S, Brüning T. Neuere Entwicklungen zum Nachweis von Schimmelpilzantigenen: Stellenwert von immunologischen Assays. Umweltmed Forsch Praxis 2012; 156-158

330. *Behrens T, *Brüning T. Potential work-related causes of dementia.
Dtsch Ärztebl 2012; 109: 283

329. *Liebers V, van Kampen V, Bünger J, Düser M, Stubel H, Brüning T, Raulf-Heimsoth M. Assessment of Airborne Exposure to Endotoxin and Pyrogenic Active Dust Using Electrostatic Dustfall Collectors (EDCs). J Toxicol Env Health A 2012; 75: 501-507 IF: 1.036

328. *Hoffmeyer F, Raulf-Heimsoth M, Lehnert M, Kendzia B, Bernard S, Berresheim H, Düser M, Henry J, Weiß T, Pesch B, Brüning T, WELDOX Group. Impact of different welding techniques on biological effect markers in exhaled breath condensate of 58 mild steel welders. J Toxicol Env Health A 2012; 75: 525-532 IF: 1.036

327. *Kendzia B, Pesch B, Marczynski B, Lotz A, Welge P, Brüning T, Raulf-Heimsoth M. Pre- and postshift levels of inflammatory biomarkers and DNA damage in non-bitumen-exposed construction workers-subpopulation of the german human bitumen study. J Toxicol Env Health A 2012; 75: 533-543 IF: 1.036

326. *Käfferlein HU, Marczynski B, Simon P, Angerer J, Rihs HP, Wilhelm M, Straif K, Pesch B, Brüning T. Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: a null result in brief. Arch Toxicol 2012; 86: 1317-1321 IF: 6.100

325. *Kopp R, Kumbartski M, Harth V, Brüning T, Käfferlein HU. Partition of metals in the maternal/fetal unit and lead-associated decreases of fetal iron and manganese: an observational. Arch Toxicol 2012; 86: 1571-81 IF: 6.100

324. *van Kampen V, Deckert A, Hoffmeyer F, Taeger D, Brinkmann E, Brüning T, Raulf-Heimsoth M, Bünger J. Symptoms, spirometry, and serum antibody concentrations among compost workers exposed to organic dust. J Toxicol Env Health A 2012; 75: 492-500 IF: 1.036

323. *Rihs HP, Lotz A, Rueff F, Landt O, Brüning T, Raulf-Heimsoth M. Impact of Interleukin-13 and -18 Promoter Polymorphisms in health care workers with natural rubber latex allergy. J Toxicol Env Health A 2012; 75: 515-524 IF: 1.036

322. *Rihs H, Marczynski B, Lotz A, Raulf-Heimsoth M, Brüning T. Modulation of oxidative DNA damage by repair enzymes XRCC1 and hOGG1. J Toxicol Env Health A 2012; 75: 588-596 IF: 1.036

321. *Peters S, Vermeulen R, Olsson A, Van GR, Kendzia B, Vincent R, Savary B, Williams N, Woldbaek T, Lavoue J, Cavallo D, Cattaneo A, Mirabelli D, Plato N, Dahmann D, Fevotte J, Pesch B, Brüning T, Straif K, Kromhout H. Development of an exposure measurement database on five lung carcinogens (ExpoSYN) for quantitative retrospective occupational exposure assessment. Ann Occup Hyg. 2012; 56: 70-79 IF: 2.241

320. *Koch H, Kolossa-Gehring M, Schröter-Kermani C, Angerer J, Brüning T. Bisphenol A in 24 h urine and plasma samples of the German Environmental Specimen Bank (ESBHum) from 1995 to 2009: a retrospective exposure evaluation. J Expo Sci Environ Epidemiol 2012; 22: 610-6 IF: 4.500

319. *Hoffmeyer F, Raulf-Heimsoth M, Weiss T, Lehnert M, Gawrych K, Kendzia B, Brüning T. Relation between biomarkers in exhaled breath condensate and internal exposure to metals from gas metal arc welding. J Breath Res 2012; 6: 027105 IF: 3.800

318. *Fartasch M, Taeger D, Broding HC, Schöneweis S, Gellert B, Pohrt U, Brüning T. Evidence of increased skin irritation after wet work: impact of water exposure and occlusion. Contact Dermatitis 2012; 67: 217-228 IF: 5.500

317. *Behrens T, Pesch B, Brüning T. Urinary bladder cancer risk factors. Cancer Epidem Biomark & Prev 2012; 21: 693 IF: 3.800

316. Behrens T, Brüning T. Ursachen einer Demenz. Dt Ärzteblatt 2012; 109: 283

315. van Kampen V, Rabente T, Lessmann H, Brüning T, Raulf-Heimsoth M, Merget R, Bünger J. Sensibilisierende Arbeitsstoffe - wie werden sie gekennzeichnet und wie werden Tätigkeiten mit ihnen geregelt? Allergologie 2012; 35: 219-228 IF: 0.500

314. *Westphal GA, Krahl J, Munack A, Ruschel Y, Schröder O, Hallier E, Brüning T, Bünger J. Mutagenicity of diesel engine exhaust is eliminated in the gas phase by an oxidation catalyst but only slightly reduced in the particle phase. Environ Sci Technol 2012; 46: 6417-24 IF: 11.400

313. *Lehnert M, Pesch B, Lotz A, Pelzer, J, Kendzia B, Gawrych K, Heinze E, Van Gelder R, Punkenburg E, Weiß T, Mattenklott M, Hahn JU, Möhlmann C, Berges M, Hartwig A, Brüning T, WELDOX Study Group. Exposure to inhalable, respiratory, and ultrafine particles in welding fume. Ann Occup Hyg 2012; 56: 557-567 IF: 2.241

312. *Johnen G, Gawrych K, Bontrup H, Pesch B, Taeger D, Banek S, Kluckert M, Wellhäußer H, Eberle F, Nasterlack M, Leng G, Stenzl A, Brüning T. Performance of Survivin mRNA as a Biomarker for Bladder Cancer in the Prospective Study UroScreen. PLoS One 2012; e35363 IF: 3.700

311. *Schütze A, Pälmke C, Angerer J, Weiß T, Brüning T, Koch HM. Quantification of biomarkers of environmental exposure to di(isononyl)cyclohexane-1, 2-dicarboxylate (DINCH) in urine via HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2012; 895-896: 123-130 IF: 1.911

310. *Lambrechts D, Truong T, Justenhoven C, Brüning T, Easton DF, Guenel P, Brauch H. 11q13 is a susceptibility locus for hormone receptor positive breast cancer. Hum Mutat 2012; 33: 1123-32 IF: 3.900

309. *Schindler BK, Koslitz S, Meier S, Belov VN, Koch HM, Weiß T, Brüning T, Käfferlein HU. Quantification of four major metabolites of embryotoxic N-Methyl and N-Ethyl-2-pyrrolidone in human urine by cooled-injection gas chromatography and isotope dilution mass spectrometry. Anal Chem 2012; 17: 3787-94 IF: 7.400

308. *Raulf-Heimsoth M, van Kampen V, Kespohl S, Sander I, Merget R, Brüning T. Inhalationsallergien am Arbeitsplatz. Bundesgesundheitsbl 2012; 55: 363-72 IF: 1.700

307. *Pesch B, Weiß T, Kendzia B, Henry J, Lehnert M, Lotz A, Heinze E, Käfferlein HU, van Gelder R, Berges M, Hahn JU, Mattenklott M, Punkenburg E, Hartwig A, Brüning T, The WELDOX Group. Levels and predictors of airborne and internal exposure to manganese and iron among welders. J Expo Sci Environ Epidemiol 2012; 22: 291-298 IF: 4.500

306. *Rabstein S, Behrens T, Brüning T. Light Exposure and Melatonin among Rotating Shift Nurses - Letter. Cancer Epidemiol Biomarkers Prev 2012; 21: 557 IF: 3.800

305. *Behrens T, Pesch B, Brüning T. Urinary bladder cancer risk factors in Egypt - Letter. Cancer Epidemiol Biomarkers Prev 2012; 21: 603 IF:3.800

304. Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Hall P, Czene K, Irwanto A, Liu J, Nevanlinna H, Aittomaki K, Blomqvist C, Meindl A, Schmutzler RK, ...,Justenhoven C, Brauch H, Brüning T, GENICA Network,..., Swann R, Velentzis L, Eccles DM, Tapper WJ, Gerty SM, Graham NJ, Ponder BA, Chenevix-Trench G, Pharoah PD, Lathrop M, Dunning AM, Rahman N, PetoJ, Easton DF. Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012; 44: 312-318 IF: 30.800

302. *Weber DG, Johnen G, Bryk O, Jöckel KH, Brüning T. Identification of miRNA-103 in the cellular fraction of human peripheral blood as a potential biomarker for malignant mesothelioma - a pilot study. PLoS One 2012; 7: e30221 IF: 3.700

301. *Monsé C, Sucker K, van Thriel C, Broding HC, Jettkant B, Berresheim H, Wiethege T, Käfferlein H, Merget R, Bünger J, Brüning T. Considerations for the design and technical setup of a human whole-body exposure chamber. Inhal Toxicol 2012; 24: 99-108 IF: 2.100

300. *Lehnert M, Kraywinkel K, Pesch B, Holleczek B, Brüning T. New malignancies following cancer of the urinary bladder: analysis of German cancer registry data. Eur J Cancer Care 2012; 21: 398-402 IF: 2.100

299. *Pesch B, Kendzia B, Gustavsson P, Jöckel KH, Johnen G, Pohlabeln H, Olsson A, Ahrens W, Gross IM, Bröske I, Wichmann HE, Merletti F, Richiardi L, Simonato, L, Fortes, C, Siemiatycki J, Parent ME, Consonni D, Landi MT, Caporaso N, Zaridze D, Cassidy A, Szeszenia-Dabrowska N, Rudnai P, Lissowska J, StückeI, Fabianova E, Dumitru RS, Bencko V, Foretova L, Janout V, Rudin CM, Brennan P, Boffetta P, Straif K, Brüning T. Cigarette smoking and lung cancer - relative risk estimates for the major histological types from a pooled analysis of case-control studies. Int J Cancer 2012; 131: 1210-1219 IF: 6.400

298. *Justenhoven C, Obazee O, Winter S, Couch FJ, Olson JE, Hall P, Hannelius U, Li J, Humphreys K, Sever G, Giles G, Southey M, Baglietto L, Fasching PA, Beckmann MW, Ekici AB, Hamann U, Baisch C, Harth V, Rabstein S, Lotz A, Pesch B, Brüning T, Ko Y, Brauch H. The postmenopausal hormone replacement therapy-related breast cancer risk is decreased in women carrying the CYP2C19*17 variant. Breast Cancer Res Tr 2012; 131: 347-350 IF: 3.800

297. *Kespohl S, Kotschy-Lang N, Tomm TM, von Bergen M, Maryska S, Brüning T, Raulf-Heimsoth M. Occupational IgE-Mediated Softwood Allergy: Characterization of the Causative Allergen. Int Arch Allergy Immunol 2012; 157: 202-208 IF: 2.800

296. *Koch HM, Haller A, Weiß T, Käfferlein HU, Stork J, Brüning T. Phthalate exposure during cold plastisol application-A human biomonitoring study. Toxicol Lett 2012; 213: 100-106 IF: 3.500

295. *Peters S, Kromhout H, Olsson AC, Wichmann HE, Brüske I, Consonni D, Landi MT, Caporas o N, Siemiatycki J, Richiardi L, Mirabelli D, Simonato L, Gustavsson P, Plato N, Jöcke KH, Ahrens W, Pohlabeln H, Boffetta P, Brennan P, Zaridze D, Cassidy A, Lissowska J, Szeszenia-Dabrowska N, Rudnai P, Fabianova E, Forastiere F, Bencko V, Foretova L, Janout V, Stücker I, Dumitru RS, Benhamou S, Bueno-de-Mesquita B, Kendzia B, Pesch B, Straif K, Brüning T, Vermeulen R. Occupational exposure to organic dust increases lung cancer risk in the general population. Thorax 2012; 67: 111-116 IF: 10.000

294. *Peters S, Vermeulen R, Portengen L, Olsson A, Kendzia B, Vincent R, Savary B, Lavoue J, Cavallo D, Cattaneo A, Mirabelli D, Plato N, Fevotte J, Pesch B, Brüning T, Straif K, Kromhout H. Modelling of occupational respirable crystalline silica exposure for quantitative exposure assessment in community-based case-control studies. J Environ Monit 2011; 13: 3262-3268 IF: 2.179

293. *Stevens KN, Garcia-Closas M, Fredericksen Z, Kosel M, Brüning T, Chang-Claude J, Hein R, Wang-Gohrke S, Anton-Culver H, Ziogas A, Couch FJ, Easton DF. Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk. Br J Cancer 2011; 105: 1934-1939 IF: 8.800

292. *Lotz A, Raulf-Heimsoth M, Brüning T, Pesch B. [Learning the Structure of DAGs or Bayesian Networks with an Example from the Human Bitumen Study. Gesundheitswesen 2011; 73: 912-914

291. *Peters S, Vermeulen R, Olsson A, Van Gelder R, Kendzia B, Vincent R, Savary B, Williams N, Woldbaek T, Lavoue J, Cavallo D, Cattaneo A, Mirabelli D, Plato N, Dahmann D, Fevotte J, Pesch B, Brüning T, Straif K, Kromhout H. Development of an Exposure Measurement Database on Five Lung Carcinogens (ExpoSYN) for Quantitative Retrospective Occupational Exposure Assessment. Ann Occup Hyg. 2011 56: 70-79 IF: 2.241

290. *Stevens KN, Vachon CM, Brauch H, GENICA Consortium, Schmidt MK, Cox A, Chang-Claude J, Yannoukakos D, Nevanlinna H, Wang X, Couch FJ. Common breast cancer susceptibility loci are associated with triple negative breast cancer. Cancer Res 2011; 71: 6240-6249 IF: 11.200

289. *Figueroa JD, Garcia-Closas M, Brauch H, Justenhoven C, Brüning T, Easton D, Spurdle AB. Associations of common variants at 1p11, 2 and 14q24, 1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011; 20: 4693-4706 IF: 3.500

288. *Milne RL, Lorenzo-Bermejo J, Burwinkel B, Hamann U, Pesch B, Ko Y The GENICA Network, Easton DF, Chenevix-Trench G. 7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium. J Med Genet 2011; 48: 698-702 IF: 4.000

287. *Broding HC, Kollner A, Brüning T, Fartasch M. Maligne Hauttumoren in beruflich verursachten Narben. Hautarzt 2011; 62: 757-763 IF: 1.198

286. *Crooke PS, Justenhoven C, Brauch H, for the GENICA-Consortium, Dawling S, Roodi N, Higginbotham KS, Plummer WD, Schuyler PA, Sanders ME, Page DL, Smith JR, Dupont WD, Parl FF. Estrogen metabolism and exposure in a genotypic-phenotypic model for breast cancer risk prediction. Cancer Epidem Biomar & Prev 2011; 20: 1502-1515 IF: 3.800

285. *Raulf-Heimsoth M, Sander I, Kespohl S, van Kampen V, Brüning T. Rare and new occupational inhalation allergens. Allergologie 2011; 34: 27-32 IF: 0.500

284. *Milne RL, Goode EL, Garcia-Closas M, Couch FJ, Harth V, for the GENICA Network, Chenevix-Trench G, Easton DF. Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer. Cancer Epidem Biomar & Prev 2011; 20: 2222-2231 IF: 3.800

283. *Dünnebier T, Schläfer K, Gilbert M, Baisch C, Justenhoven C, Brauch H, Harth V, Spickenheuer A, Rabstein S, Pesch B, Brüning T, Ko YD, Hamann U. No association of polymorphisms in the cell polarity gene SCRIB with breast cancer risk. Breast Canc Res Treat 2011; 127: 259-264 IF: 3.800

282. *Broding HC, van der Pol A, de Sterke J, Monse C, Fartasch M, Brüning T. In vivo Monitoring of epidermal absorption of hazardous substances by confocal Raman micro-spectroscopy. J Dtsch Dermatol Ges 2011; 9: 618-627

281. *Zahradnik E, Sander I, Kendzia B, Fleischer, C, Brüning T, Raulf-Heimsoth M. Passive airborne dust sampling to assess mite antigen exposure in farming environments. J Environ Monit 2011; 13: 2638-2644 IF: 2.179

280. *Rabstein S, Spickenheuer A, Pesch B, Brüning T, Schwab M, Brauch H. The earwax-associated SNP c, 538G>A (G180R) in ABCC11 is not associated with breast cancer risk in Europeans. Breast Cancer Res 2011; 129: 993-999 IF: 7.400

279. *Käfferlein HU, Rühl R, Brüning T. Trichloromethane and paint stripping. Gefahrst Reinhalt Luft 2011; 71: 255-263 IF: 0.300

278. *Broeks A, Schmidt MK, Sherman ME, Brüning T, Pesch B, Pharoah PD, Garcia-Closas M. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: Findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011; 20: 3289-3303 IF: 3.500

277. *Sander I, Rozynek P, Rihs HP, van Kampen V, Chew FT, Lee WS, Kotschy-Lang N, Merget R, Brüning T, Raulf-Heimsoth M. Multiple wheat flour allergens and cross-reactive carbohydrate determinants bind IgE in baker's asthma. Allergy 2011; 66: 1208-1215 IF: 12.400

276. *Nasterlack M, Feil G, Leng G, Pesch B, Huber S, Sievert KD, Johnen G, Taeger D, Mayer T, Kluckert M, Brüning T, Stenzl A. Das Screening von Harnblasenkarzinomen mittels urinbasierter Tumormarker - Erfahrungen aus der Arbeitsmedizin. Aktuelle Urol 2011; 42: 128-134 IF: 0.300

275. *Welge P, Marczynski B, Raulf-Heimsoth M, Spickenheuer A, Kendzia B, Heinze E, Angerer J, Käfferlein HU, Pesch B, Brüning T. Assessment of micronuclei in lymphocytes from workers exposed to vapours and aerosols of bitumen. Arch Toxicol 2011; 85: 65-71 IF: 6.100

274. *Marczynski B, Raulf-Heimsoth M, Spickenheuer A, Pesch B Kendzia B, Mensing T, Engelhardt B, Eun-Hyun L, Schindler BK, Heinze E, Welge P, Bramer R, Angerer J, Breuer D, Käfferlein HU, Brüning T. DNA adducts and strand breaks in workers exposed to vapours and aerosols of bitumen: associations between exposure and effect. Arch Toxicol 2011; 85: 53-64 IF: 6.100

273. *Broding HC, Monsé C, Brüning T, Fartasch M. Induction of occupational leucoderma and vitiligo: Can butylated hydroxytoluene induce vitiligo similarly to p-tert-butylphenol? Hautarzt 2011; 62: 209-214 IF: 1.198

272. *Raulf-Heimsoth M, Pesch B, Kendzia B, Spickenheuer A, Bramer R, Marczynski B, Merget R, Brüning T. Irritative effects of vapours and aerosols of bitumen on the airways assessed by non-invasive methods. Arch Toxicol 2011; 85: 41-52 IF: 6.100

271. *Koch HM, Wittassek M, Brüning T, Angerer J, Heudorf U. Exposure to phthalates in 5-6 years old primary school starters in Germany - A human biomonitoring study and a cumulative risk assessment. Int J Hyg Env Health 2011; 214: 188-195 IF: 6.000

270. *Raulf-Heimsoth M, Pesch B, Rühl R, Brüning T. The Human Bitumen Study: executive summary. Arch Toxicol 2011; 85: 3-9 IF: 6.100

269. *Breuer D, Hahn JU, Höber D, Emmel C, Musanke U, Rühl R, Spickenheuer A, Raulf-Heimsoth M, Bramer R, Seidel A, Schilling B, Heinze E, Kendzia B, Marczynski B, Welge P, Angerer J, Brüning T, Pesch B. Air sampling and determination of vapours and aerosols of bitumen and polycyclic aromatic hydrocarbons in the Human Bitumen Study. Arch Toxicol 2011; 85: 11-20 IF: 6.100

268. *Raulf-Heimsoth M, Marczynski B, Spickenheuer A, Pesch B, Welge P, Rühl R, Bramer R, Kendzia B, Heinze E, Angerer J, Brüning T. Bitumen workers handling mastic versus rolled asphalt in a tunnel: assessment of exposure and biomarkers of irritation and genotoxicity. Arch Toxicol 2011; 85: 81-87 IF: 6.100

267. *Pesch B, Spickenheuer A, Kendzia B, Schindler BK, Welge P, Marczynski B, Rihs HP, Raulf-Heimsoth M, Angerer J, Brüning T. Urinary metabolites of polycyclic aromatic hydrocarbons in workers exposed to vapours and aerosols of bitumen. Arch Toxicol 2011; 85: 29-39 IF: 6.100

266. *Rihs HP, Spickenheuer A, Heinze E, Pesch B, Raulf-Heimsoth M, Angerer J, Brüning T. Modulation of urinary polycyclic aromatic hydrocarbon metabolites by enzyme polymorphisms in workers of the German Human Bitumen Study. Arch Toxicol 2011; 85: 73-79 IF: 6.100

265. *Spickenheuer A, Rühl R, Hober D, Raulf-Heimsoth M, Marczynski B, Welge P, Breuer D, Gabriel S, Musanke U, Rode P, Heinze E , Kendzia B, Bramer R, Knecht U, Hahn JU, Brüning T, Pesch B. Levels and determinants of exposure to vapours and aerosols of bitumen. Arch Toxicol 2011; 85: 21-28 IF: 6.100

264. *Taeger D, Brüning T, Pesch B, Müller KM, Wiethege T, Johnen G, Wesch H, Dahmann D, Hoffmann W. Association between lymph node silicosis and lung silicosis in 4,384 german uranium miners with lung cancer. Arch Env Occup Health 2011; 66: 34-42 IF: 1.800

263. *Wittassek M, Koch H, Angerer J, Brüning T. Assessing exposure to phthalates - The human biomonitoring approach. Mol Nutr Food Res 2011 55: 7-31 IF: 5.200

262. *Zahradnik E, Sander I, Bruckmaier LE, Flagge A, Fleischer C, Schierl R, Nowak D, Sültz J, Spickenheuer A, Noss I, Brüning T, Raulf-Heimsoth M. Development of a sandwich ELISA to measure exposure to occupational cow hair allergens. Int Arch Allergy Immunol 2011; 155: 225-233 IF: 2.800

261. *Merget R, Sander I, van Kampen V, Beckmann U, Heinze E, Raulf-Heimsoth M, Brüning T. Allergic asthma after flour inhalation in subjects without occupational exposure to flours: an experimental pilot study. Int Arch Occup Med Environ Health 2011; 84: 753-760 IF: 3.000

260. *Hoffmeyer F, Weiß T, Lehnert M, Pesch B, Berresheim H, Henry J, Raulf-Heimsoth M, Broding HC, Bünger J, Harth V, Brüning T. Increased metal concentrations in exhaled breath condensate of industrial welders. J Environ Monit 2011; 13: 212-218 IF: 2.179

259. *Olsson AC, Gustavsson P, Pesch B, Siemiatycki J, Pintos J, Brüning T, Groß IM, Kendzia B, Forastiere F, Bueno-de-Mesquita B, Brennan P, Boffetta P, Straif K. Exposure to Diesel Motor Exhaust and Lung Cancer Risk in a Pooled Analysis from Case-Control Studies in Europe and Canada. Am J Respir Crit Care Med 2011; 183: 941-948 IF: 24.700

258. *Pesch B, Nasterlack M, Eberle F, Bonberg N, Taeger D, Leng G, Feil G, Johnen G, Ickstadt K, Kluckert M, Wellhäußer H, Stenzl A, Brüning T. The role of haematuria in bladder cancer screening among men with former occupational exposure to aromatic amines. BJUI 2011; 108: 546-552 IF: 4.500

257. *Yang XR, Chang-Claude J, Goode EL, Couch FJ, Nevanlinna H, Milne RL, Gaudet M, Schmidt MK, Broeks A, Cox A, Fasching PA, ..., Brüning T ,..., Hankinson SE, Hunter DJ, Tamimi R, Sangrajrang S, Brennan P, McKay J, Odefrey F, Gaborieau V, Devilee P, Huijts PE, Tollenaar R, Seynaeve C, Dite GS, Apicella C, Hopper JL, Hammet F, Tsimiklis H, Smith LD, Southey MC, Humphreys MK, Easton D, Pharoah P, Sherman ME, Garcia-Closas M. Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the breast cancer association consortium studies. J Natl Cancer Inst 2011; 103: 250-263 IF: 13.757

256. *Justenhoven C, Winter S, Dünnebier T, Hamann U, Baisch C, Rabstein S, Spickenheuer A, Harth V, Pesch B, Brüning T, Ko Y, Brauch H. Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk. Breast Cancer Res Tr 2011; 13: 563-569 IF: 3.800

255. *Gube M, Taeger D, Weber DG, Brand P, Johnen G, Müller-Lux A, Gro&szl;ig I, Wiethege T, Weber A, Raithel HJ, Kraus T, Brüning T. Performance of biomarkers SMRP, CA125, and CYFRA 21-1 as potential tumor markers for malignant mesothelioma and lung cancer in a cohort of workers formerly exposed to asbestos. Arch Toxicol 2011; 85: 185-192 IF: 6.100

254. *Milne RL, Gaudet MM, Spurdle AM, Fasching PA, Couch FJ, Benitez J, Rias Perez JI, Zamora MP, Malats N, Dos Santos Silva I, Brüning T, Garcia-Closas M, Goode EL, Chang-Claude J. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the Breast Cancer Association Consortium: a combined case-control study. Breast Cancer Res 2010; 12: R110 IF: 7.400

253. *Hoffmeyer F, Henry J, Borowitzki G, Merget R, Bünger J, Brüning T, Raulf-Heimsoth M. Pulmonary lesions and serum levels of soluble Fas (sCD95) in former hard coal miners.
Eur J Med Res 2010; 15: 60-63 IF: 4.200

252. *Liebers V, Brinkert S, Stubel H, Brüning T, Raulf-Heimsoth M. Organic Dust at Workplaces: Measurement of Pyrogenic Activity. Pneumologie 2010; 64: 619-625 IF: 1.200

251. *Henry J, Casjens C, Schikowski T, Stachon A, Germing A, Ranft U, Lehnert M, Harth V, Krämer U, Brüning T, Pesch B. Prohepcidin, B-Type Natriuretic Peptide, and Iron Status in a cohort of elderly women from the Rhine-Ruhr Area. Acta Haematol 2010; 124: 129-133 IF: 2.400

250. *Weber DG, Casjens C, Rozynek P, Lehnert M, Zilch-Schöneweis S, Bryk O, Taeger D, Gomolka M, Kreuzer M, Otten H, Pesch B, Johnen G, Brüning T. Assessment of mRNA and microRNA stabilization in peripheral human blood for multicenter studies and biobanks. Biomarker Insights 2010; 5: 95-102

249. *Fletcher O, Johnson N, Dos Santos Silva I, Orr N, Ashworth A, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, Burwinkel B, Bartram CR, Meindl A,..., for the GENICA Network,... Missense Variants in ATM in 26, 101 Breast Cancer Cases and 29, 842 Controls. Cancer Epidem Biomar & Prev 2010; 19: 2143-2151 IF: 3.800

248. Pesch B, Harth V, Rabstein S, Pallapies D, Brüning T. Entwicklung eines Instruments zur Erfassung von Schichtarbeit. Zbl Arbeitsmedizin 2010; 60: 314-315

247. Rabstein S, Pesch B, Harth V, Bonberg N, Heinze E, Pallapies D, Schiffermann M, Spickenheuer A, Baisch C, Brüning T, GENICA Consortium. Untersuchung von Eigenangaben zu Schichtarbeit. Zbl Arbeitsmedizin 2010; 60: 316-317

246. Wiethege T, Rozynek P, Brüning T. Genetische Untersuchungen im Arbeitsleben - Deutsches Gen-Diagnostikgesetz tritt in Kraft. ÖFAM 2010; 1: 11-15

245. Weiß T, Henry J, Brüning T. Berufskrankheit 1301: Bewertung der beruflichen (Mit-)Verursachung von Harnblasenerkrankungen unter Berücksichtigung der quantitativen Abschätzung der Einwirkung der aromatischen Amine 2-Naphtylamin, 4-Aminobiphenyl und o-Toluidin. ASU 2010; 45: 222-235

244. Pesch B, Feil G, Brüning T, Nasterlack M, Johnen G, Taeger D, Sievert K-D, Leng G, Stenzl A, und die UroScreen-Studiengruppe. Prospektive Studie UroScreen: Früherkennung von Harnblasenkarzinomen mit Tumormarkern in einem Kollektiv mit vorheriger beruflicher Exposition gegenüber aromatischen Aminen. ASU 2010; 45: 467-472

243. *Schikowski T, Ranft U, Sugiri D, Vierkötter A, Brüning T, Harth V, Krämer U. Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women. Resp Res 2010; 22: 113 IF: 5.800

242. *Justenhoven C, Winter S, Hamann U, Haas S, Fischer H-P, Pesch B, Brüning T, Ko Y, Brauch H for the GENICA Network. The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors. Cancer 2010; 116: 5358-64 IF: 6.200

241. *Justenhoven C, Schaeffeler E, Winter S, Baisch C, Hamann U, Harth V, Rabstein S, Spickenheuer A, Pesch B, Brüning T, Ko Y, Schwab M, Brauch H. Combined UGT1A1 and UGT1A6 genotypes together with a stressful life event increase breast cancer risk. Breast Cancer Res Tr 2010; 24: 289-292 IF: 3.800

240. Pallapies D, Pesch B, Johnen G, Rabstein S, Raulf-Heimsoth M, Welge P, Brüning T, Harth V. Schichtarbeit und Krebs? - Aktueller Kenntnisstand und offene Fragen. ASU 2010; 45: 411-415

239. *Liebers V, Brinkert S, Stubel H, Brüning T, Raulf-Heimsoth M. Organic dust at workplaces: Measurement of pyrogenic activity. Pneumologie 2010; 64: 619-625 IF: 1.200

238. *Raiko I, Sander I, Weber DG, Raulf-Heimsoth M, Gillissen A, Kollmeier J, Scherpereel A, Brüning T, Johnen G. Development of an enzyme-linked immunosorbent assay for the detection of human calretinin in plasma and serum of mesothelioma patients. BMC Cancer 2010 2810:242 IF: 3.800

237. *Monsé C, Broding HC, Hoffmeye F, Jettkant B, Berresheim H, Brüning T, Bünger J, Sucker K. Use of a Calibration Gas Generator for Irritation Threshold Assessment and As Supplement of Dynamic Dilution Olfactometry. Chem Senses 2010; 39: 523-30 IF: 3.500

236. *Kespohl S, Schlünssen V, Jacobsen G, Schaumburg I, Maryska S, Meurer U, Brüning T, Sigsgaard T, Raulf-Heimsoth M. Impact of cross-reactive carbohydrate determinants on wood dust sensitization. Clin Exp Allergy 2010 40: 1099-1106 IF: 6.100

235. *The MARIE-GENICA Consortium. Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy. Int J Cancer 2010; 126: 2935-2946 IF: 6.400

234. *Merget R, van Kampen V, Sucker K, Heinze E , Taeger D, Goldscheid N, Haufs MG, Raulf-Heimsoth M, Kromark K, Nienhaus A, Brüning T. The German experience 10 years after the latex allergy epidemic: need for further preventive measures in healthcare employees with latex allergy. Int Arch Occup Env Health 2010; 83: 895-893 IF: 3.000

233. *van Thriel C, Schäper M, Kleinbeck S, Kiesswetter E, Blaszkewicz M, Golka K, Nies E, Raulf-Heimsoth M, Brüning T. Sensory and pulmonary effects of acute exposure to sulfur dioxide (SO(2)). Toxicol Lett 2010 196: 42-50 IF: 3.500

232. *Horstmann M, Bontrup H, Hennenlotter J, Taeger D, Weber A, Pesch B, Feil G, Patschan O, Johnen G, Stenzl A, Brüning T. Clinical experience with survivin as a biomarker for urothelial bladder cancer. World J Urol 2010; 28: 399-404 IF: 3.400

231. *Marczynski B, Raulf-Heimsoth M, Pesch B, Kendzia B, Käfferlein HU, Vosshans B, Borowitzki G, Lee EH, Bramer R, Brüning T. Detection of DNA strand breaks by comet assay in sputum leucocytes of bitumen-exposed workers: A pilot study. Hum Exp Toxicol 2010; 29: 721-729 IF: 2.800

230. *Weber DG, Johnen G, Taeger D, Weber A, Gro&szl;ig IM, Pesch B, Kraus T, Brüning T, Gube M. Assessment of Confounding Factors Affecting the Tumor Markers SMRP, CA125, and CYFRA21-1 in Serum. Biomark Insights 2010; 5: 1-8

229. *Käfferlein HU, Marczynski B, Mensing T, Brüning T. Albumin and hemoglobin adducts of benzo[a]pyrene in humans - Analytical methods, exposure assessment, and resommendations for future directions. Crit Rev Toxicol 2010; 40: 126-150 IF: 5.900

228. *Westphal GA, Krahl J, Brüning T, Hallier J, Bünger J. Ether oxygenate additives in gasoline reduce toxicity of exhausts. Toxicology 2010; 268: 198-203 IF: 4.500

227. *Pesch B, Harth V, Rabstein S, Baisch C, Schiffermann M, Pallapies D, Bonberg N, Heinze E, Spickenheuer A, Justenhoven C, Brauch H, Hamann U, Ko Y, Straif K, Brüning T. Night work and breast cancer - results from the German GENICA study. Scand J Work Environ Health 2010; 36: 134-141 IF: 6.300

226. *Rabstein S, Brüning T, Harth V, Fischer HP, Haas S, Weiß T, Spickenheuer A, Pierl C, Justenhoven C, Illig T, Vollmert C, Baisch C, Ko Y, Hamann U, Brauch H, Pesch B, for the GENICA Network. N-acetyltransferase 2, exposure to aromatic and heterocyclic amines, and receptor-defined breast cancer. Eur J Cancer Prev 2010 19: 100-109 IF: 2.400

225. *Merget R, Sander I, van Kampen V, Raulf-Heimsoth M, Ulmer HM, Kulzer R, Brüning T. Occupational immediate-type asthma and rhinitis due to Rhodium salts.'
Am J Ind Med 2010 53: 42-46 IF: 3.500

224. *Andonova IE, Justenhoven C, Winter S, Hamann U, Baisch C, Rabstein S, Spickenheuer A, Harth V, Pesch B, Brüning T, Ko Y, Ganev V, Brauch H. No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk. Breast Cancer Res Tr 2010; 121: 185-194 IF: 3.800

223. *Raulf-Heimsoth M, Hoffmeyer F, van Thriel C, Blaszkewicz M, Bünger J, Brüning T. Assessment of low dose effects of acute sulphur dioxide exposure on the airways using non-invasive methods. Arch Toxicol 2010; 84:121-127 IF: 6.100

222. *Pesch B, Taeger D, Johnen G, Groß I, Weber DG, Gube M, Müller-Lux A, Heinze E, Wiethege T, Neumann V, Tannapfel A, Raithel J, Brüning T, Kraus T. Cancer mortality in a surveillance cohort of German males formerly exposed to asbestos. Int J Hyg Env Health 2010; 213: 44-51 IF: 6.000

221. *Dünnebier T, Bermejo JL, Haas S, Fischer HP, Pierl CB, Justenhoven C, Brauch H, Baisch C, Gilbert M, Harth V, Spickenheuer A, Rabstein S, Pesch B, Brüning T, Ko Y, Hamann U. Polymorphisms in the UBC9 and PIAS3 genes of the SUMO-conjugating system and breast cancer risk. Breast Cancer Res Tr 2010; 121: 185-194 IF: 3.800

220. *The MARIE-GENICA Consortium. Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women. Breast Cancer Res Tr 2010; 120: 727-736 IF: 3.800

219. *The MARIE-GENICA Consortium. Postmenopausal Estrogen Monotherapy Associated Breast Cancer Risk is Modified by CYP17A1_-34_T>C Polymorphism". Breast Cancer Res Tr 2010; 120: 737-744 IF: 3.800

218. *Wang X, Fredericksen ZS, Vierkant RA, Kosel ML, Pankratz VS, Cerhan JR, Justenhoven C, Brauch H, GENICA Consortium, Olson JE, Couch FJ. Association of genetic variation in mitotic kinases with breast cancer risk. Breast Cancer Res Tr 2010; 119: 453-462 IF: 3.800

217. *Breuer D, Schneider W, Weiß T, Castillo M, Koch H, Brüning T. Passivrauchbelastung in der Gastronomie - Messungen von Nikotin und Acrylnitril in der Luft in gastronomischen Betrieben. Gefahrst Reinhalt Luft 2009; 10: 411-416 IF: 0.300

216. *Hoffmeyer F, Raulf-Heimsoth M, Harth V, Bünger J, Brüning T. Comparative analysis of selected exhaled breath biomarkers obtained with two different temperature-controlled devices. BMC Pulm Med 2009; 9: 48 IF: 3.100

215. *van Kampen V, Merget R, Rabstein S, Sander I, Brüning T, Broding HC, Keller C, Muesken H, Overlack A, Schultze-Werninghaus G, Walusiak J, Raulf-Heimsoth M. Comparison of wheat and rye flour solutions for skin prick testing: a multi-centre study (Stad 1). Clin Exp Allergy 2009; 39: 1896-1902 IF: 6.100

214. Brüning T. Gendiagnostikgesetz verabschiedet - Forschung, Arbeitsmedizin und Politik sind gefordert. ASU 2009; 44: 469-470

213. *Hey K, Juran S, Schäper M, Kleinbeck S, Kiesswetter E, Blaszkewicz M, Golka K, Brüning T, van Thriel C. Neurobehavioral effects during exposures to propionic acid - an indicator of chemosensory distraction? Neurotox 2009; 30: 1223-1232 IF: 3.400

212. *Hoffmeyer F, Raulf-Heimsoth M, Merget R, Brüning T. EBC: A new matrix for assessment of airway and lung inflammation current aspects of environmental and occupational medicine. Pneumologie 2009; 63: 426-432 IF: 1.200

211. *Gaudet MM, Milne RL, Cox A, Camp NJ, Goode EL, Humphreys MK, Dunning AM, Morrison J, Sigurdson AJ, Alexander BH, Bhatti P, len-Brady K, Cannon-Albright LA, Wong J, Chenevix-Trench G, Spurdle AB, Beesley J, Pharoah PD, Easton DF, Garcia-Closas M, Breast Cancer Association Consortium. Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. Cancer Epidemiol Biomar & Prev 2009; 18: 1610-1616 IF: 3.800

210. *Milne RL, Benitez J, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, Arias JI, Zamora MP, Brinton LA, Chang-Claude J, Wang-Gohrke S, Shen CY, Wang HC, Yu JC, Chen ST, Bermisheva M, Nikolaeva T, Khusnutdinova E, Humphreys MK, Morrison J, Platte R, Easton DF, Breast Cancer Association Consortium. Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst 2009; 101: 1012-1018 IF: 13.757

209. *Marczynski B, Pesch B, Wilhelm M, Rossbach B, Preuss R, Hahn JU, Rabstein S, Raulf-Heimsoth M, Seidel A, Rihs HP, Adams A, Scherenberg M, Erkes A, Engelhardt B, Straif K, Käfferlein HU, Angerer J, Brüning T. Occupational exposure to polycyclic aromatic hydrocarbons and DNA damage by industry: a nationwide study in Germany. Arch Toxicol 2009; 83: 947-957 IF: 6.100

208. *Pesch B, Weiß T, Van Gelder R, Westphal G, Pallapies D, Brüning T. Low-dose extrapolation in toxicology: an old controversy revisited. Arch Toxicol 2009; 83: 639-640 IF: 6.100

207. *Hoffmeyer F, Harth V, Bünger J, Brüning T, Raulf-Heimsoth M. Leukotriene B4, 8-iso-Prostaglandin F2A and pH in exhaled breath condensate from asymptomatic smokers. J Physiol Pharmacol 2009; 60: 57-60 IF: 2.200

206. Pesch B, Spickenheuer A, Taeger D, Brüning T. Berufliche Chrom (VI)-Exposition und Lungenkrebsrisiko. ASU 2009; 44: 336-344

205. *Dünning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodriguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S,..., GENICA,..., Morrison J, Pharoah PD, Pooley KA, Chenevix-Trench G, BCAC. Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet 2009; 18: 1131-1139 IF: 3.500

204. *The MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk. Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. Breast Cancer Res Tr 2009; 119: 463-474 IF: 3.800

203. *Rihs HP, Hoffmeyer F, Brüning T. DNA Repair: From the mechanisms to the Impact on occupational research. Pneumologie 2009; 63: 319-324 IF: 1.200

202. *Slowicki A, Käfferlein HU, Brüning T. Azofarbmittel - Teil 1: Eigenschaften, Aufnahme über die Haut und Metabolismus. Gefahrst Reinhalt Luft 2009; 69: 263-268 IF: 0.300

201. *Sander I, Fleischer C, Meurer U, Brüning T, Raulf-Heimsoth M. Allergen content of grass pollen preparations for skin prick testing and sublingual immunotherapy. Allergy 2009; 64: 1486-1492 IF: 12.400

200. *Liebers V, Stubel H, Düser M, Brüning T, Raulf-Heimsoth M. Standardization of whole blood assay for determination of pyrogenic activity in organic dust samples. Int J Hyg Env Health 2009; 212 547-556 IF: 6.000

199. *Ahmed S, Thomas G, Ghoussaini M, Healey CS, Humphreys MK, The GENICA Consortium. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23,2. Nat Genet. 2009; 41: 585-590 IF: 30.800

198. *Dünnebier T, Bermejo JL, Haas S, Fischer HP, Pierl CB, Justenhoven C, Brauch H, Baisch C, Gilbert M, Harth V, Spickenheuer A, Rabstein S, Pesch B, Brüning T, Ko Y, Hamann U. Common variants in the UBC9 gene encoding the SUMO-conjugating enzyme are associated with breast tumor grade. Int J Cancer 2009 125: 596-602 IF: 6.400

197. *Merget R, Sander I, Ewig S, Sennekamp J, Brüning T. Consort hypersensitivity pneumonitis. Eur Respir J 2009; 33: 1223-1225 IF: 24.300

196. *Justenhoven C, Hamann U, Pierl CB, Baisch C, Harth V, Rabstein S, Spickenheuer A, Pesch B, Brüning T, Winter S, Ko Y, Brauch H. CYP2C19*17 is associated with decreased breast cancer risk. Breast Cancer Res Tr 2009; 115: 391-396 IF: 3.800

195. *Taeger D, Johnen G, Wiethege T, Soile T, Tannapfel A, Müller KM, Brüning T, Pesch B. Major histopathological patterns of lung cancer related to arsenic exposure in German uranium miners. Int Arch Occup Env Health 2009; 82: 867-875 IF: 3.000

194. *Justenhoven C, Pierl CB, Haas S, Fischer HP, Hamann U, Baisch C, Harth V, Vollmert C, Illig T, Pesch B, Brüning T, Dippon J, Ko Y, Brauch H. Polymorphic loci of E2F2, CCND1, and CCND3 are associated with HER2 status of breast tumors. Breast Cancer Res Tr 2008; 124: 2077-2081 IF: 3.800

193. *Hoffmeyer F, Raulf-Heimsoth M, Brüning T. Exhaled breath condensate and airway inflammation. Curr Opin Allergy Clin Immunol 2008; 9: 16-22 IF: 2.800

192. *Justenhoven C, Pierl CB, Haas S, Fischer HP, Baisch C, Hamann U, Harth V, Pesch B, Brüning T, Vollmert C, Illig T, Dippon J, Ko Y, Brauch H. The CYP1B1_1358_GG genotype is associated with estrogen receptor-negative breast cancer. Breast Cancer Res Tr 2008; 111: 171-177 IF: 3.800

191. *Haas S, Gevensleben H, Rabstein S, Harth V, Pesch B, Brüning T, Justenhoven C, Brauch H, Hamann U, Ko Y, Baisch C, Fischer HP, Büttner R. Expression of heregulin, phosphorylated HER-2, HER-3 and HER-4 in HER-2 negative breast cancers. Oncology Rep 2008; 21: 299-304 IF: 4.200

190. *Merget R, Jörres RA, Heinze E, Haufs MG, Taeger D, Brüning T. Development of a 1-concentration-4-step dosimeter protocol for methacholine testing. Respir Med 2008; 103: 607-613 IF: 4.300

189. *van Kampen V, Merget R, Brüning T. Occupational allergies to phytase. Pneumologie 2008; 62: 707-710 IF: 1.200

188. *Kespohl S, Sander I, Schulze J, Poppe M, Brüning T, Raulf-Heimsoth M.
Development of an obeche wood allergen quantification assay for the assessment of allergen exposure in workplaces. Scand J Work Environ Health 2008; 34: 387-395 IF: 6.300

187. *Kleinbeck S, Juran SA, Kiesswetter E, Schäper M, Blaszkewicz M, Brüning T, van Thriel C. Evaluation of ethyl acetate on three dimensions: Investigation of behavioral, physiological and psychological indicators of adverse chemosensory effects. Toxicol Lett 2008; 182: 102-109 IF: 3.500

186. *Ji Y, Olson J, Zhang J, Hildebrandt M, Wang L, Ingle J, Fredericksen Z, Sellers T, Miller W, Dixon JM, Brauch H, Eichelbaum M, Justenhoven C, Hamann U, Ko Y, Brüning T, Chang-Claude J, Wang-Gohrke S, Schaid D, Weinshilboum R. Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Res 2008 68: 5997-6005 IF: 11.200

185. *Garcia-Closas M, Hall P, Nevanlinna H, Pooley K, Morrison J, Richesson DA, Bojesen SE, Nordestgaard BG, Axelsson CK, Arias JI, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Zamora P, Brauch H, Justenhoven C, Hamann U, Ko Y, Brüning T, Haas S, Dork T, Schurmann P, ..., Tyrer J, Ponder BA, Sangrajrang S, Brennan P, McKay J, Odefrey F, Gabrieau V, Sigurdson A, Doody M, Struewing JP, Alexander B, Easton DF, Pharoah PD. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008; 254: e1000054 IF: 4.500

184. *Taeger D, Krahn U, Wiethege T, Ickstadt K, Johnen G, Eisenmenger A, Wesch H, Pesch B, Brüning T. A study on lung cancer mortality related to radon, quartz, and arsenic exposures in German uranium miners. J Toxicol Env Health A 2008; 71: 859-865 IF: 1.036

183. *Ickstadt K, Schäfer M, Fritsch A, Schwender H, Abel J, Bolt HM, Brüning T, Ko Y, Vetter H, Harth V. Statistical methods for detecting genetic interactions: a head and neck squamous-cell cancer study. J Toxicol Env Health A 2008; 71: 803-815 IF: 1.036

182. *Rabstein S, Unfried K, Ranft U, Illig T, Kolz M, Mambetova C, Vlad M, Roman C, Weiß T, Becker D, Brüning T, Pesch B. Lack of association of delta-aminolevulinate dehydratase polymorphisms with blood lead levels and hemoglobin in Romanian women from a lead-contaminated region. J Toxicol Env Health A 2008; 71: 716-724 IF: 1.036

181. *Rihs HP, Marczynski B, Rabstein S, Scherenberg M, Landt O, Brüning T. Rapid detection of the hOGG1 Ser326Cys polymorphism using LightCyler technology. J Toxicol Env Health A 2008; 71: 877-880 IF: 1.036

180. *Harth V, Schäfer M, Abel J, Maintz L, Neuhaus T, Besuden M, Primke R, Wilkesmann A, Thier R, Vetter H, Ko Y, Brüning T, Bolt HA, Ickstadt K. Head and neck squamous cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair.
J Toxicol Env Health A 2008; 71: 887-897 IF: 1.036

179. *Rihs HP, Triebig G, Werner P, Rabstein S, Heinze E, Pesch B, Brüning T. Association between genetic polymorphisms in styrene-metabolizing enzymes and biomarkers in styrene-exposed workers. J Toxicol Environ Health Part A 2008; 71: 866-873 IF: 1.036

178. *Seidel A, Spickenheuer A, Straif K, Rihs HP, Marczynski B, Scherenber M, Dettbarn G, Angerer J, Wilhelm M, Brüning T, Jacob J, Pesch B. New Biomarkers of occupational exposure to polycyclic aromatic hydrocarbons. J Toxicol Env Health A 2008; 71: 734-745 IF: 1.036

177. *Raulf-Heimsoth M, Angerer J, Pesch B, Marczynski B, Hahn HJ, Spickenheuer A, Preuss, R, Rühl R, Rode P, Brüning T. Biological monitoring as a useful tool for the detection of a coal-tar contamination in bitumen-exposed workers. J Toxicol Env Health A 2008; 71: 746-750 IF: 1.036

176. *Sander I, Fleischer C, Borowitzki G, Brüning T, Raulf-Heimsoth M. Development of a two-site enzyme immunoassay based on monoclonal antibodies to measure airborne exposure to (1-->3)-beta-d-glucan. J Immunol Methods 2008; 337: 55-62 IF: 2.200

175. *Frank B, Wiestler M Kropp S, Hemminki K, Spurdle AB, Sutter C, Wappenschmidt B, Chen X, Beesley J, Hopper JL, Meindl A, Kiechle M, Slanger T, Bugert P, Schmutzler RK, Bartram CR, Flesch-Janys D, Mutschelknauss E, Ashton K, Salazar R, Web E, Hamann U, Brauch H, Justenhoven C, Ko Y, Brüning T, Silva Idos S, Johnson N, Pharoah PP, Dunning AM, Pooley KA, Chang-Claude J, Easton DF, Peto J, Houlston R, Chenevix-Trench G, Fletcher O, Burwinkel B. Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. J Natl Cancer Inst 2008; 100: 437-442 IF: 13.757

174. *Merget R, Sander I, Rozynek P, Raulf-Heimsoth M, Brüning T. Occupational hypersensitivity pneumonitis due to molds in an Onion and potato sorter. Am J Ind Med 2008; 51: 117-119 IF: 3.500

173. *Liebers V, Raulf-Heimsoth M, Brüning T. Health effects due to endotoxin inhalation (review). Arch Toxicol 2008; 82: 203-210 IF: 6.100

172. *van Kampen V, Rabstein S, Merget R, Brüning T, Broding HC, Keller C, Müsken H, Overlack A, Schultze-Werninghaus G, Walusiak J, Raulf-Heimsoth M. Prediction of challenge test results by flour, specific IgE and skin prick test in symptomatic bakers. Allergy 2008; 63: 897-902 IF: 12.400

171. Pesch B, Brüning T. Lungenkrebsrisiko bei Edelstahlschweißern. ASU 2008; 43: 300-302

170. *Dahmann D, Taeger D, Kappler M, Büchte S, Morfeld P, Brüning T, Pesch B. Assessment of exposure in epidemiological studies - the example of silica dust. J Expo Sci Environ Epidemiol 2008; 18: 452-461 IF: 4.500

169. *van Kampen V, Merget R, Butz, M, Taeger D, Brüning T. Trends in Suspected and Recognized Occupational Respiratory Diseases in Germany between 1970 and 2005. Am J Ind Med 2008; 51: 492-502 IF: 3.500

168. *Justenhoven C, Pierl CB, Haas S, Fischer HP, Baisch C, Hamann U, Harth V, Pesch B, Brüning T, Vollmert C, Illig T, Dippon J, Ko Y, Brauch H. The CYP1B1_1358_GG genotype is associated with estrogen receptor-negative breast cancer. Breast Cancer Res Tr 2008; 108: 137-149 IF: 3.800

167. *Frank B, Rigas SH, Bermejo JL, Wiestler M, Wagner K, Hemminki K, Reed MW, Sutter C, Wappenschmidt B, Balasubramanian SP, Meindl A, Kiechle M, Bugert P, Schmutzler RK, Bartram CR, Justenhoven C, Ko Y, Brüning T, Brauch H, Hamann U, Pharoah PP, Dunning AM, Pooley KA, Easton DF, Cox A, Burwinkel B. The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study. Breast Cancer Res Tr 2008; 111: 139-144 IF: 3.800

166. *Pesch B, Pierl CB, Gebel M, Gross I, Becker D, Johnen G, Rihs HP, Donhuijsen K, Lepentsiotis V, Meier M, Schulze J, Brüning T. Occupational risks for adenocarcinoma of the nasal cavity and paranasal sinuses in the German wood industry. Occup Environ Med 2008; 65: 191-196 IF: 4.900

165. *Förster K, Preuss R, Rossbach B, Brüning T, Angerer J, Simon P. 3-Hydroxybenzo[a]pyrene in the urine of workers with occupational exposure to polycyclic aromatic hydrocarbons in different industries. Occup Environ Med 2008; 65: 224-229 IF: 4.900

164. *Merget R, Sander I, Rozynek P, Heinze E, Imoehl M, Raulf-Heimsoth M, Brüning T. Occupational immunoglobulin E-mediated asthma due to Penicillium camemberti in a dry-sausage packer. Respiration 2008 76: 109-111 IF: 3.700

163. *Hoffmeyer F, Harth V, Merget R, Goldscheid N, Heinze E, Degens PO, Pesch B, Bünger J, Brüning T, Raulf-Heimsoth M. Exhaled breath condensate analysis: Evaluation of a methodological setting for an occupational field study. J Physiol Pharmacol 2007; 58: 289-298 IF: 2.200

162. *Liebers V, Raulf-Heimsoth M, Linsel G, Goldscheid N, Düser M, Stubel H, Brüning T. Evaluation of quantification methods of occupational endotoxin exposure. J Toxicol Env Health 2007; 70: 1798-1805 IF: 1.036

161. *Weber D, Taeger D, Pesch B, Kraus T, Brüning T, Johnen G. Soluble mesothelin-related peptides (SMRP) - High stability of a potential tumor marker for mesothelioma. Cancer Biomarkers 2007; 3: 287-92 IF: 3.100

160. *Raulf-Heimsoth M, Liebers V, Brüning T. Mechanism of endotoxin action and pattern of diseases. Gefahrst Reinhalt Luft 2007; 67: 351-353 IF: 0.300

159. *Hoffmeyer F, van Kampen V, Brüning T, Merget R. Pneumokoniosen.
Pneumologie 2007; 67: 1-24 IF: 1.200

158. Brüning T, Merget R, Wiethege T. Expertengespräch "Begutachtungs- und Entschädigungspraxis geringgradiger (niedrig gestreuter) Silikosen". ASU 2007; 42: 660-661

157. Liebers V, Kraus T, Brüning T, Raulf-Heimsoth M. Byssinose - eine aktuelle Übersicht. ASU 2007; 9: 469-474

156. *Sander I, Zahradnik E, Bogdanovic J, Raulf-Heimsoth M, Wouters I, Renstrom A, Harris-Roberts J, Robinson E, Rodrigo M, Goldscheid N, Brüning T, Doekes G. Optimized methods for fungal alpha-amylase airborne exposure assessment in bakeries and mills. Clin Exp Allergy 2007; 37: 1229-1238 IF:6.100

154. *Pesch B, Kappler M, Straif K, Marczynski B, Preuss R, Rossbach B, Rihs HP, Weiß T, Rabstein S, Pierl C, Scherenberg M, Adams A, Käfferlein HU, Angerer J, Wilhelm M, Seidel A, Brüning T. Dose-response modeling of occupational exposure to polycyclic aromatic hydrocarbons with biomarkers of exposure and effect. Cancer Epidem Biomar & Prev 2007; 16: 1863-1873 IF: 3.800

153. *Raulf-Heimsoth M, Kespohl S, Crespo JF, Rodriguez J, Feliu A, Brüning T, Rihs HP. Natural rubber latex and chestnut allergy: cross-reactivity or co-sensitization? Allergy 2007 62: 1277-1281 IF: 12.400

152. *Weiß T, Brüning T, Bolt HM. Dephenylation of the rubber chemical N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine: a classical problem revisited. Crit Rev Toxicol 2007; 37: 553-566 IF: 5.900

151. *Wiesenhütter K, Selinski S, Golka K, Brüning T, Bolt HM. Re-assessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethylene-exposed workers. Int Arch Occup Env Health 2007 81: 247-251 IF: 3.000

150. Raulf-Heimsoth M, Zahradnik E, Koets M, van Amerongen A, Tolba R, Sander I, Doekes G, Brüning T. Semiquantitative Schnelltestmethode für den Nachweis von Allergenen am Arbeitsplatz. ErgoMed 2007; 2: 30-33

149. Pierl CB, Rabstein S, Harth V, Brüning T, Brauch H, Fischer HP, Hamann U, Justenhoven C, Ko Y, Pesch B
Menopausal status and factors affecting cessation of menses in the region of Bonn. Germany
CEJoM 2007; 2: 190-202

148. *Raulf-Heimsoth M, Pesch B, Spickenheuer A, Schott K, Marczynski B, Breuer D, Hahn JU, Merget R, Brüning T Assessment of irritative effects of fumes of bitumen on the airways by using non-invasive methods - results of a cross-shift study in mastic asphalt workers. J Occup Env Hyg 2007; 4: 223-227 IF: 2.000

147. *Rihs HP, Raulf-Heimsoth M, Spickenheuer A, Rabstein S, Pesch B, Schott K, Bramer R, Angerer J, Hahn JU, Brüning T. Determination of sequence variants of metabolizing enzymes after occupational exposure to fumes of bitumen under high processing temperatures. J Occup Env Hyg 2007; 4: 65-71 IF: 2.000

146. *Marczynski B, Raulf-Heimsoth M, Spickenheuer A, Mensing T, Welge P, Förster K, Angerer J, Pesch B, Bramer R, Käfferlein HU, Breuer D, Hahn JU, Brüning T. Ambient and Biological Monitoring of exposure and genotoxic effects in mastic asphalt workers exposed to fumes of bitumen. J Occup Env Health 2007; 4: 127-136 IF: 3.000

145. *Raulf-Heimsoth M, Brüning T, Rihs HP. Recombinant latex allergens. Rev Francaise Allergologie et d'Immunologie Clin 2007; 47: 123-125 IF: 0.241

144. Drexler H, Brüning T. Prävention von arbeitsbedingten Hauterkrankungen.
Die BG 2007; 03: 109-111

143. *Bünger J, Krahl J, Munack A, Ruschel Y, Schröder O, Emmert B, Westphal G, Müller M, Hallier E, Brüning T. Strong mutagenic effects of diesel engine emissions using vegetable oil as fuel. Arch Toxicol 2007; 81: 599-603 IF: 6.100

142. *van Kampen V, Merget R, Brüning T. Occupational allergies to Bromelain. Pneumologie 2007;61: 159-161 IF: 1.200

141. *Raulf-Heimsoth M, Pesch B, Schott K, Kappler M, Preuss R, Marczynski B, Angerer J, Rihs HP, Hahn JU, Merget R, Brüning T. Irritative effects of fumes and aerosols of bitumen on the airways: results of a cross-shift study. Arch Toxicol 2007: 81: 35-44 IF 6.100

140. *Raulf-Heimsoth M, Pesch B, Schott K, Kappler M, Preuss R, Marczynski B, Angerer J, Rihs HP, Hahn JU, Merget R, Brüning T. Irritative effects of fumes and aerosols of bitumen on the airways: results of a cross, shift study. Arch Toxicol 2007; 81: 35-44 IF: 6.100

139. *Rihs HP, John A, Scherenberg M, Seidel A, Brüning T. Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay. Clin Chim Acta 2007; 376: 240-3 IF: 5.000

138. *Harth V, Merget R, Altmann L, Brüning T. Bronchial challenge testing to fragrance component as further diagnostic approach to non-immune immediate contact reactions. Contact Dermatitis 2007; 56: 175-7 IF: 5.500

137. Blome O, Brüning T, Kamrad E, Kranig A, Piekarski C, Wiethege T, Letzel S. Fachgespräch zur Synkanzerogenese am 25. und 26. November in Hennef. Die BG 2006; 3: 121-4

136. *Geh S, Yucel R, Duffin R, Albrecht C, Borm PJ, Armbruster L, Raulf-Heimsoth M, Brüning T, Hoffmann E, Rettenmeier AW, Dopp E. Cellular uptake and cytotoxic potential of respirable bentonite particles with different quartz contents and chemical modifications in human lung fibroblasts. Arch Toxicol 2006; 80: 98-106 IF: 6.100

135. Harth V, Brüning T. Für Prävention und Gesundheitsförderung am Arbeitsplatz. Medical Tribune 2006; 51/52: 38-9

134. Käfferlein HU, Wiethege T, Brüning T. Aus der Arbeitsschutzforschung: Tonerstäube so schlecht wie ihr Ruf? Die BG 2006; 11: 532-3

133. *Preuss R, Rossbach B, Wilhelm M, Brüning T, Angerer J. External and internal exposure to polycyclic aromatic hydrocarbons (PAH) among workers in the production of fire-proof materials - Proposal of a biological monitoring guidance value. Int J Hyg Env Health 2006; 209: 575-580 IF: 6.000

132. *Rihs HP, Rueff F, Lundberg M, Rozynek P, Barber D, Scheurer S, Cistero-Bahima A, Brüning T, Raulf-Heimsoth M. Relevance of the recombinant lipid transfer protein of Hevea brasiliensis: IgE-binding reactivity in fruit-allergic adults. Ann Allergy Asthma & Immunology 2006; 97: 643-649 IF: 5.900

131. *Sander I, Liebers V, Brüning T, Raulf-Heimsoth M. Neue Methoden zum Nachweis von Endotoxin und Glukan. Allergologie 2006; 29: 446-448 IF: 0.500

130. *Taeger D, Pesch B, Johnen G, Wiethege T, Eisenmenger A, Wesch H, Müller KM, Brüning T. Silikose als modifizierender Faktor auf die Verteilung der führenden histomorphologischen Typen bösartiger Lungentumoren unter kumulativer Quarzexposition. Gefahrst Reinhalt Luft 2006; 66: 450-454 IF: 0.300

129. Taeger D, Johnen G, Pesch B, Wiethege T, Tannapfel A, Brüning T. Das Wismut-Sektionsarchiv: Wertvolle Quelle für die berufsgenossenschaftliche Forschung. Die BG 2006; 356-357

128. *Zahradnik E, Koets M, Sander I, Tolba R, van Amerongen A, Doekes G, Renstrom A, Brüning T, Raulf-Heimsoth M. Detection of occupational aeroallergens - Application of a semi-quantitative rapid assay. Gefahrst Reinhalt Luft 2006; 66: 120-124 IF: 0.300

127. *Kranig A, Brüning T, Harth V. Wann ist eine Erkrankung eine Berufskrankheit? Grundlagen der deutschen BK-Systematik. DMW 2006; 131: 2202-2203

126. *Rozynek P, Rihs HP, Gaspar A, Brüning T, Raulf-Heimsoth M. The new Hev b 7,02 iso-allergen from Hevea brasiliensis is an important allergen for health care workers and spina bifida patients. Allergy 2006; 61: 508-509 IF 12.400

125. *Kespohl S, Merget R, Overlack A, Brüning T, Raulf-Heimsoth M.
Detection of novel occupational wood allergens in locust wood dust (Robinia pseudoacacia L. ) J Allergy Clin Immunol 2006; 118: 522-524 IF 14.200

124. *Preuss R, Rossbach B, Wilhelm M, Brüning T, Angerer J. External and internal exposure to polycyclic aromatic hydrocarbons (PAH) among workers in the production of fire-proof materials - Proposal of a biological monitoring guidance value. Int J Hyg Env Health 2006; 209: 575-580 IF 6.000

123. *Sander I, Raulf-Heimsoth M, Wiemer K, Kespoh S, Brüning T, Merget R. Sensitization due to Gum Arabic (Acacia senegal): The Cause of Occupational Allergic Asthma or Crossreaction to Carbohydrates? Int Arch Allergy Immunol 2006; 27: 141: 51-56 IF 3.767

122. *Haas S, Pierl C, Harth V, Pesch B, Rabstein S, Brüning T, Ko Y, Hamann U, Justenhoven C, Brauch H, Fischer HP. Expression of xenobiotic and steroid hormone metabolizing enzymes in human breast carcinomas. Int J Cancer 2006: 119: 1785-1791 IF 6.400

121. *Liebers V, Brüning T, Raulf-Heimsoth M. Occupational endotoxin exposure and possible health effects on humans. Am J Ind Med 2006; 49: 474-491 IF 3.500

120. *Bünger J, Krahl J, Weigel A, Schröder O, Brüning T, Müller M, Hallier E, Westphal G. Influence of fuel properties, nitrogen oxides, and exhaust treatment by an oxidation catalytic converter on the mutagenicity of diesel engine emissions. Arch Toxicol 2006; 80 : 540 -546 IF: 6.100

119. *Marczynski B, Raulf-Heimsoth M, Preuss R, Kapplwe M, Schott K, Pesch P, Zoubek G, Hahn JU, Mensing T, Angerer J, Käfferlein HU, Brüning T. Assessment of DNA damage in WBCs of workers occupationally exposed to fumes and aerosols of bitumen. Cancer Epidem Biomar & Prev 2006; 15: 645-651 IF: 3.800

118. *Rabstein S, Unfried K, Ranft U, Illig T, Kolz M, Rihs HP, Mambetova C, Vlad M, Brüning T, Pesch B. Variation of the N-acetyltransferase 2 gene in a romanian and a kyrgyz population. Cancer Epidem Biomar & Prev 2006; 15: 138-141 IF: 3.800

117. *Taeger D, Fritsch A, Wiethege T, Johnen G, Eisenmenger A, Wesch H, Ko Y, Stier S, Michael MK, Brüning T, Pesch B. Role of exposure to radon and silicosis on the cell type of lung carcinoma in German uranium miners. Cancer 2006; 106: 881-889 IF: 6.200

116. *van Thriel C, Schaper M, Kiesswetter E, Kleinbeck S, Juran S, Blaszkewicz M, Fricke HH, Altmann L, Berresheim H, Brüning T. From chemosensory thresholds to whole body exposures-experimental approaches evaluating chemosensory effects of chemicals. Int Arch Occup Env Health 2006; 79: 308-321 IF: 3.000

115. *Harth V, Raulf-Heimsoth M, Brüning T, Merget R. Isolated late asthmatic reaction after exposure to ammonium persulfate in a hairdresser. Contact Dermatitis 2006; 54: 62-63 IF: 5.500

114. *Geh S, Yucel R, Duffin R, Albrecht C, Borm PJ, Armbruster L, Raulf-Heimsoth M, Brüning T, Hoffmann E, Rettenmeier AW, Dopp E. Cellular uptake and cytotoxic potential of respirable bentonite particles with different quartz contents and chemical modifications in human lung fibroblasts. Arch Toxicol 2006; 80: 98-106 IF: 6.100

113. *Rashid MU, Jakubowska A, Justenhoven C, Harth V, Pesch B, Baisch C, Pierl C, Brüning T, Ko Y, Benner A, Wichmann HE, Brauch H, Hamann U. German populations with infrequent CHEK2*1100delC and minor associations with early-onset and familial breast cancer. Eur J Cancer 2005; 41: 2896-2903 IF: 8.400

112. Triebig G, Baur X, Brüning T, Schiele R. Arbeitsmedizinische Leitlinien der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e. V. Arbeit unter Einwirkung von Cadmium und seinen Verbindungen. ASU 2005; 11: 657-658

111. Triebig G, Baur X, Brüning T, Schiele R. Arbeitsmedizinischen Leitlinien der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. Arbeit und Einwirkung von Blei und seinen Verbindungen.
ASU 2005; 40: 11: 611-612

110. *Rihs HP, Kowal A, Raulf-Heimsoth M, Degens PO, Landt O, Brüning T
Rapid detection of the SPINK5 polymorphism Glu420Lys by Real-Time PCR.
Clin Chim Acta 2005; 355: 185-189 IF: 5.000

109. Bolm-Audorff U, Brandenburg S, Brüning T, Dupuis H, Ellegast R, Elsner G, Franz K, Grasshoff H, Grosser V, Hanisch L, Hartmann B, Hartung E, Heuchert G, Jäger M, Krämer J, Kranig A, Hering KG, Ludolph E, Luttmann A, Nienhaus A, Pieper W, Pöhl KD, Remé T, Riede D, Rompe G, Schäfer K, Schilling S, Schmitt E, Schröter F, Seidler A, Spallek M, Weber M.
Medizinische Beurteilungskriterien zu bandscheibenbedingten Berufskrankheiten der Lendenwirbelsäule (I) Konsensempfehlungen zur Zusammenhangsbegutachtung der auf Anregung des HVBG eingerichteten interdisziplinären Arbeitsgruppe. Trauma Berufskrankh 2005; 3: 211-252

108. *Pesch B, Ko Y, Brauch H, Hamann U, Harth V, Rabstein S, Pierl C, Fischer HP, Baisch C, Justenhoven C, Ranft U, Brüning T for the GENICA-Network. Factors modifying the association between hormone-replacement therapy and breast cancer risk. Eur J Epidem 2005; 20: 699-711 IF: 13.600

107. Kespohl S, Merget R, Brüning T, Raulf-Heimsoth M. Immunglobulin-E-vermittelte Allergien durch Holzstäube - Identifizierung eines Majorallergens aus Abachiholz. Allergo J 2005; 14: 402-407 IF: 1.100

106. *van Kampen V, Merget R, Brüning T. Occupational allergies to papain. Pneumologie 2005; 59: 405-410 IF: 1.200

105. *Merget R, Johnen G, Pesch B, Brüning T. Lung cancer screening revisited - are we merely combing a giraffe? Pneumologie 2005; 59: 165-166 IF: 1.200

104. *Harth V, Bolt HM, Brüning T. Cancer of the urinary bladder in highly exposed workers in the production of dinitrotoluenes: a case report. Int Arch Occup Env Health 2005; 20: 103-118 IF: 3.000

103. *Harth V, Brüning T, Bolt HM. Renal carcinogenicity of trichloroethylene: update, mode of action, and fundamentals for occupational standard setting. Rev Environ Health 2005; 20: 103-118

102 *Kespohl S, Sander I, Merget R, Petersen A, Meyer HE, Sickmann A, Brüning T, Raulf-Heimsoth M. Identification of an obeche (Triplochiton scleroxylon) wood allergen as a class I chitinase. Allergy 2005; 60: 808-814 IF: 12.400

101. Brüning T, Weiß T, Käfferlein HU, Mensing T, Bolt HM. Nierenzellkarzinome durch Trichlorethen - Kriterien für die Anerkennung als Berufskrankheit der Nr. 1302 (Erkrankungen durch Halogenkohlenwasserstoffe) der Anlage zur BKV. ASU 2005; 6: 354-356

100. *Preuss R, Drexler H, Böttcher M, Wilhelm M, Brüning T, Angerer J. Current external and internal exposure to naphtalene of workers occupationally exposed to polycyclic aromatic hydrocarbons in different industries. Int Arch Occup Env Health 2005; 78: 377-362 IF: 3.000

099. *Sander I, Kespohl S, Merget R, Goldscheid N, Degens PO, Brüning T, Raulf-Heimsoth M. A new method to bind allergens for the measurement of specific IgE antibodies. Int Arch Allergy Immunol 2005; 136: 39-44 IF: 3.767

098. *Rihs HP, Kowal A, Raulf-Heimsoth M, Degens PO, Landt O, Brüning T. Rapid detection of the SPINK5 polymorphism Glu420Lys by real-time PCR technology. Clin Chim Acta 2005; 355: 185-189 IF: 5.000

097. *Rihs HP, Pesch B, Kappler M, Rabstein S, Rossbach B, Angerer J, Scherenberg M, Adams A, Wilhelm M, Seidel A, Brüning T. Occupational exposure to polycyclic aromatic hydrocarbons in German industries: Association between exogenous exposure and urinary metabolites and its modulation by enzyme polymorphisms. Toxicol Lett 2005; 157: 241-255 IF: 3.500

096. *Käfferlein HU, Ferstl C, Burkhart-Reichl A, Hennebruder K, Drexler H, Brüning T, Angerer J. The use of biomarkers of exposure of N, N-dimethylformamide in health risk assessment and occupational hygiene in the polyacrylic fibre industry. Occup Environ Med 2005; 62: 330-336 IF: 4.900

095. *Abraham BK, Justenhoven C, Pesch B, Harth V, Weirich, G, Baisch C, Rabstein S, Ko Y, Brüning T, Fischer HP, Haas S, Brod S, Oberkanins C, Hamann U, Brauch H, for the GENICA Network. Investigation of genetic pathways of genes of the hemochromatosis pathway and their role in breast cancer. Cancer Epidem Biomar & Prev 2005; 14: 1102-1107 IF: 3.800

094. *Mensing T, Marczynski B, Engehardt B, Wilhelm M, Preuss P, Kappler M, Angerer J, Käfferlein HU, Scherenberg M, Seidel A, Brüning T. DNA adduct formation of benzo[a]pyrene in white blood cells of workers exposed to polycyclic aromatic hydrocarbons. Int J Hyg Env Health 2005; 208: 173-178 IF: 6.000

093. Bolt HM, Brüning T, Greim H. Tagungsbericht über das internationale Symposium zur Toxizität von Benzol. ASU 2005; 40: 272-276

092. *Marczynski B, Preuss R, Mensing T, Angerer J, Seidel A, El Mourabit A, Wilhelm M, Brüning T. Genotoxic risk assessment in white blood cells of occupationally exposed workers before and after alteration of the polycyclic aromatic hydrocarbon (PAH) profile in the production material: comparison with PAH air and urinary metabolite levels. Int Arch Occup Env Health 2005; Mar 78: 97-108 IF: 3.000

091. *Marczynski B, Merget R, Mensing T, Rabstein S, Kappler M, Bracht A, Haufs MG, Käfferlein HU, Brüning T. DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure. Arch Toxicol 2005; 79: 355-362 IF: 6.100

090. *Schulte-Mattler WJ, Kley RA, Rothenfusser-Korber E, Bohm S, Brüning T. Hackemann J, Steinbrecher A, During MV, Voss B, Vorgerd M. Immune-mediated rippling muscle disease. Neurology 2005; 64: 364-7 IF: 9.900

089. van Kampen V, Haamann F, Merget R, Sander I, Raulf-Heimsoth M, Brüning T.
Der Weg zur Standardallergiediagnostik der Typ-I-Allergie. Atemw Lungenkrkh 2004; 30: 382-384

088. Schott K, Zoubek G, Rumler R, Schicker H, Rühl R, Brüning T, Raulf-Heimsoth M. Chemisch irritative Wirkung von Gussasphaltdämpfen und -aerosolen auf Atemwege bei Heißverarbeitung. Tiefbau 2004; 10: 668-673

087. *Sander I, Kespoh S, Merget R, Goldscheid N, Degens P, Brüning T, Raulf-Heimsoth M. A new method to bind allergens for the measurement of specific IgE antibodies. Int Arch Allergy Immunol 2004; 136: 39-44 IF: 3.767

086. *Justenhoven C, Hamann U, Pesch B, Harth V, Rabstein S, Baisch C, Vollmert C, Illig T, Ko Y, Brüning T, Brauch H, for the Interdisciplinary Study Group on Gene Environment Interactions and Breast Cancer in Germany Network. ERCC2 genotypes and a corresponding haplotype are linked with the breast cancer risk in a german population. Cancer Epid, Biomarkers & Prevention 2004; 13: 2059-2064 IF: 3.800

085. van Kampen V, Merget R, Brüning T. Beruf und Atemwegserkrankungen. Symposium Medical 2004; 15: 12-13

084. Brüning T. Aus der Arbeitsschutzforschung: Die Rolle verschiedener Einwirkungen bei der Krebsentstehung - Synkanzerogenese. Die BG 2004; 5: 252

083. Raulf-Heimsoth M, Rihs HP, Sander I, Merget R, Brüning T. Naturlatexallergie Immer noch ein aktuelles Problem? Trauma Berufskrankh 2004; 6: 140-143

082. Raulf-Heimsoth M, Rozynek P, Sander I, Brüning T, Rihs HP. Naturlatexallergie: molekulare Grundlagen und Kreuzreaktivitäten. Allergo J 2004; 13: 328-336 IF: 1.100

081 *Rozynek P, Gilges S, Brüning T, Wilhelm M. Quality test of the MicroSeq D2 LSU Fungal Sequencing Kit for the identification of fungi. Int J Hyg Env Health 2004; 206: 297-299 IF: 6.000

080. Käfferlein HU, Marczynski B, Brüning T. Biologisches Monitoring von Kanzerogenen. Zbl Arbeitsmedizin 2004; 39: 376-388

079. *Raulf-Heimsoth M, Rozynek P, Brüning T, Rihs HP. Characterization of B- and T-cell responses and HLA-DR4 binding motifs of the latex allergen Hev b 6, 01 (prohevein) and its post-trancriptionally formed proteins Hev b 6, 02 and Hev b 6, 03. Allergy 2004 59: 724-733 IF: 12.400

078. *Brauch H, Weirich G, Klein B, Rabstein S, Bolt HM, Brüning T. VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference? Toxicol Lett 2004; 151: 301-310 IF: 3.500

077. *Pesch B, Düsing R, Rabstein S, Harth V, Grentrup D, Brüning T, Landt O, Vetter H, Ko Y. Polymorphic metabolic susceptibility genes and longevity: a study in octogonarians. Toxicol Lett 2004; 151: 283-290 IF: 3.500

076. *Schwender H, Zucknick M, Ickstadt K, Bolt HM. The GENICA network: A pilot study on the application of statistical classification procedures to molecular epidemiological data. Toxicol Lett 2004; 151: 291-299 IF: 3.500

075. *Pesch B, Brüning T, Frentzel-Beyme R, Johnen G, Harth V, Hoffmann W, Ko Y, Ranft U, Traugott UG, Thier R, Taeger D, Bolt HM. Challenges to environmental toxicology and epidemiology: where do we stand and which way do we go? Toxicol Lett 2004; 151: 255-265 IF: 3.500

074. *Neuhaus T, Ko Y, Lorenzen K, Fronhoffs S, Harth V, Bröde P, Vetter H, Bolt HM, Pesch B, Brüning T. Association of cytochrome P450 2E1 polymorphisms and head and neck squamous cell cancer. Toxicol Lett 2004; 151: 273-282 IF: 3.500

073. *Liebers V, Brüning T, Raulf-Heimsoth M. Berufliche Endotoxinexposition und mögliche Gesundheitsgefährdung für den Menschen. Gefahrst Reinhalt Luft 2004; 64: 207-216 IF: 0.300

072. *Sander I, Merget R, Degens P, Goldscheid N, Brüning T, Raulf-Heimsoth M. Comparison of wheat and rye flour skin prick test solutions for diagnosis of baker's asthma. Allergy 2004; 59: 95-98 IF: 12.400

071 *Merget R, Brüning T. Compensation of low profusion coalworkers' pneumoconiosis, new occupational disease, New convention or leave it as it is? Pneumologie 2004; 58: 107-115 IF: 1.200

070. Seidler A, Bolm-Audorff U, Brüning T, Franz K, Heuchert G, Korn M, Krämer J, Pieper W, Schmitt E. Epidemiologische Evidenz zum Zusammenhang zwischen Rauchen, Übergewicht sowie Arteriosklerose und strukturellen Bandscheibenschäden. ASU 2004; 39: 67-78

069. *Bolt HM, Lammert M, Selinski S, Brüning T. Urinary alpha(1)-microglobulin excretion as biomarker of renal toxicity in trichloroethylene-exposed persons. Int Arch Occup Env Health 2004; 77: 186-190 IF: 3.000

068. *van Kampen V, Merget R, Brüning T. Occupational allergies to xylanases. Pneumologie 2004: 58: 103-106 IF: 1.200

067. Brüning T, Giesen T, Harth V, Ko Y, Lewalter J, Pesch B. Bewertung von Suszeptibilitätsmarkern in der Arbeits- und Umweltmedizin. ASU 2004 1: 4-11

066. Raulf-Heimsoth M, Sander I, Rihs HP, Merget R, Brüning T.
Latexallergie am Wendepunkt? Medical special 2003; 4: 55-56

065. Raulf-Heimsoth M, Rihs HP, Brüning T. Latex: a new target for standardization.
Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M, 2003; 94: 107-115

064. Pesch B, Brüning T, Frentzel-Beyme R, Harth V, Hoffmann W, Ko Y, Ranft U, Steinmüller KH, Tschirbs S. Challenge to Molecular Epidemiology: the Promise of the European Research Area. European Epimarker 2003; 7: 1-5

063. Raulf-Heimsoth M, Sander I, Rihs HP, Merget R, Brüning T. Latexallergie: Aktuelle Bestandsaufnahme. Akt Dermatol 2003; 29: 176-184

062. *Merget R, van Kampen V, Brüning T. Immediate type allergies due to metal compounds: platinum salts. Pneumologie 2003; 57: 606-610 IF: 1.200

061. *van Kampen V, Merget R, Brüning T. Immediate type allergies due to metal - nickel. Pneumologie 2003; 57: 557-670 IF: 1.200

060. *Mensing T, Fricke HH, Marek W, Voss B, Brüning T, Wilhelm M. Airway responsiveness of rabbits after exposure to 2-octyl-dodecanol. AIHA Journal 2003; 64: 461-466

059. Schott K, Raulf-Heimsoth M, Angerer J, Hahn H, Heger M, Preuss R, Rohde P, Rühl R, Zozbek G, Brüning T. Auffälligkeiten bei einer Gussasphaltkolonne -Ursachenklärung einer erhöhten PAK-Belastung. ASU 2003 38: 594-597

058. *Kubisch C, Schoser BG, von During M, Betz RC, Goebel HH, Zahn S, Ehrbrecht A, Aasly J, Schroers A, Popovic N, Lochmuller H, Schroder JM, Brüning T, Malin JP, Fricke B, Meinck HM, Torbergsen T, Engels H, Voss B, Vorgerd M. Homozygous mutations in caveolin-3 cause a severe form of rippling muscle disease. Ann Neurol 2003 53: 512-520 IF: 11.200

057. *Thier R, Brüning T, Roos PH, Rihs HP, Golka K, Ko Y, Bolt HM. Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, Nat and GST genes. Int J Hyg Env Health 2003; 206: 149-171 IF 6.000

056. *Schulze J, Brüning T, Donhuijsen K, Kleine B, Pesch B, Raulf-Heimsoth M, Schröder H, Wolf J. Comments on the recommendation of the scientific committee on occupational exposure limits (SCOEL) for wood dust. Gefahrst Reinhalt Luft 2003; 63: 99 - 104 IF: 0.300

055. *Olten D, Korn M, Mensing T, Brüning T, Merget R. Airway and lung diseases by metal working fluids. Pneumologie 2003; 57: 212-221 IF: 1.200

054. *Rihs HP, Dumont B, Rozynek P, Lundberg M, Cremer R, Brüning T, Raulf-Heimsoth M. Molecular cloning, purification, and IgE-binding of a recombinant class I chitinase from Hevea brasiliensis leaves (rHev b 11, 012). Allergy 2003; 58: 246-251 IF: 12.400

053. *van Kampen V, Lessmann H, Brüning T, Merget R. Occupational allergies to cellulases. Pneumologie 2003; 57: 388-391 IF: 1.200

052. *Marczynski B, Merget R, Teschner B, Korn M, Rabstein S, Brüning T
Changes in low molecular weight DNA fragmentation in white blood cells after diisocyanate exposure of workers. Arch Toxicol 2003; 77: 470-476 IF: 6.100

051. *Brüning T, Pesch B, Wiesenhütter B, Rabstein S, Lammert M, Baumüller A, Bolt HM.
Renal cell cancer risk and occupational exposure to trichloroethylene: Results of a consecutive case-control study in Arnsberg, Germany. Am J Ind Med 2003; 43: 274-285 IF: 3.500

050. *Wenghöfer M, Pesch B, Harth V, Bröde P, Fronhoffs S, Landt O, Brüning T, Abel J, Bolt HM, Herberhold C, Vetter H, Ko Y. Association between head and neck cancer and microsomal epoxide hydrolase genotypes. Arch Toxicol 2003; 77: 37-41 IF: 6.100

049. *Merget R, Kulzer R, Kniffka A, Alt F, Breitstadt R, Brüning T. Platinum concentrations in sera of catalyst production workers are not predictive of platinum salt allergy. Int J Hyg Env Health 2002; 205: 347-351 IF: 6.000

048. *Rihs HP, Chen Z, Rueff F, Cremer R, Raulf-Heimsoth M, Baur X, Moneret-Vautrin DA, Brüning T. HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy. J Allergy Clin Immunol 2002; 110: 507-514 IF: 14.200

047. *Brüning T, Thier R, Bolt HM. Nephrotoxicity and Nephrocarcinogenicity of dinitrotoluene: New aspects to be considered. Rev Env Health 2002; 17: 75-84

046. *Thier R, Brüning T, Roos P, Bolt HM. Cytochrome P-450 1B1, a new keystone in gene-environment interactions related to human head-and-neck cancer? Arch Toxicol 2002; 76: 249-256 IF: 6.100

045. *Rozynek P, Sander I, Appenzeller U, Crameri R, Baur X, Clarke B, Brüning T, Raulf-Heimsoth M. TPIS – an IgE-binding wheat protein. Allergy 2002 57: 463 IF: 12.400

044. *Fronhoffs S, Totzke G, Stier S, Wernert N, Rothe M, Brüning T, Koch B, Sachinidis A, Vette H, Ko Y. A method for the rapid construction of cRNA standard curves in quantitative real-time reverse transcription polymerase chain reaction. Mol Cell Probes 2002; 16: 99-110 IF: 3.300

043. *Raulf-Heimsoth M, Stark R, Sander I, Maryska S, Rihs HP, Brüning T, Voshaar T. Anaphylactic reaction to apple juice containing acerola: Cross-reactivity to latex due to prohevein. J Allergy Clin Immunol 2002; 109: 715-716 IF: 14.200

042. *Czuppon AB, Merget R, Raulf-Heimsoth M, Brüning T. Comparison of IgE antibody concentrations to pyromellitic dianhydride-modified laminin and human serum albumin in sera of exposed workers with respiratory complaints. Int Arch Allergy Immunol 2002; 127: 79-81 IF: 3.767

041 *Marczynski B, Rihs HP, Rossbach B, Holzer J, Angerer J, Scherenberg M, Hoffmann G, Brüning T, Wilhelm M. Analysis of 8-oxo-7, 8-dihydro-2'-deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms. Carcinogenesis 2002; 23: 273-281 IF: 4.700

038. Raulf-Heimsoth M, Rozynek P, Sander I, Brüning T, Rihs HP. Latexallergie: Vom Patienten zur Epitopanalyse. Allergie + Asthma, Naturheilverfahren 2002 29-31

037. *Thier R, Golka K, Brüning T, Ko Y, Bolt HM. Genetic susceptibility to environmental toxicants: the interface between human and experimental studies in the development of new toxicological concepts. Toxicol Lett 2002; 127: 321-327 IF: 3.500

036. *Fronhoffs S, Brüning T, Ortiz-Pallardo E, Bröde P, Koch B, Harth V, Sachinidis A, Bolt HM, Herberhold C, Vetter H, Ko Y. Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.
Carcinogenesis 2001 22: 1405-1412 IF: 4.700 Contributed equally

035. *Totzke G, Brüning T, Vetter H, Schulze-Osthoff K, Ko Y. p53 downregulation in myelodysplastic syndrome - a quantitative analysis by competitive RT-PCR. Leukemia 2001; 15: 1663-1664 IF: 11.400

034. *Raulf-Heimsoth M, Sander I, Merget R, Brüning T. Aktuelle allergologische Probleme in der Arbeitsmedizin. Bundesgesundheitsblatt 2001 44: 654-665 IF: 1.700

033. *Ko Y, Abel J, Harth V, Bröde P, Antony Ch, Donat S, Fischer HP, Ortiz-Pallardo ME, Thier R, Sachinidis A, Vetter H, Bolt HM, Herberhold C, Brüning T. Association of CYP1B1 Codon 432 mutant allele in head and neck squamous cell cancer is reflected by somatic mutations of p53 in tumor tissue. Cancer Res 2001 61: 4398-4404 IF: 11.200

032. *Brüning T, Thier R, Mann H, Melzer H, Bröde P, Dallner G, Bolt HM. Pathological excretion patterns of urinary proteins in miners highly exposed to Dinitrotoluene. J Occ Environ Med 2001 43: 610-615 IF: 3.200

031. *Lottermoser K, Düsing R, Ervens P, Brüning T, Koch B, Sachinidis A, Vetter H, Ko Y. The plasminogen activator inhibitor-1 (PAI-1) 4G/5G poly-morphism is not associated with longevity: a study in octogenarians. J Mol Med 2001; 79: 289-293 IF: 4.700

030. *Harth V, Brüning T, Abel J, Koch B, Berg I, Sachinidis A, Bolt HM, Vetter H, Ko Y.
Real-time genotyping of cytochrom P4501A1 A4889G and T6235C polymorphism. Mol Cell Probes 2001; 15: 93-97 IF: 3.300

029. *Delbanco EH, Bolt HM, Hube WW, Beken S, Geller F, Philippou S, Brands FH, Brüning T, Thier R. Glutathione transferase activities in renal carcinomas and adjacent normal renal tissues: factors influencing renal carcinogenesis induced by xenobiotics. Arch Toxicol 2001; 74: 688-694 IF: 6.100

028. *Ortiz-Pallardó E, Zhou H, Fischer H, Sachinidis A, Vetter H, Brüning T, Ko Y. Rapid analysis of alpha-1-antitrypsin PiZ genotype by a real-time PCR approach. J Mol Med 2000; 78: 212-216 IF: 4.700

027. *De Smet K, Brüning T, Blaskewicz M, Bolt HM, Vercruysse A, Rogiers V. Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes. Arch Toxicol 2000; 74: 587-592 IF: 6.100

026. *Brüning T, Bolt HM. Renal Toxicity and Carcinogenicity of Trichloro-ethylene: Key Results, Mechanisms and Controversies. Crit Rev Toxicol 2000; 30: 253-285 IF: 5.900

025. *Vamvakas S, Brüning T, Bolt HM, Henschler D, Ulm K. Renal cell cancer correlated with occupational exposure to trichloroethylene. J Cancer Res Clin Oncol 2000; 126: 178-180 IF: 3.600

024. *Ko Y, Koch B, Harth V, Sachinidis A, Thier R, Vetter H, Bolt HM Brüning T. Rapid analysis of GSTM1, GSTT1 and GSTP1 polymorphisms using real time PCR. Pharmacogenetics 2000; 10: 271-274 IF: 2.600

023. *Harth V, Donat S, Ko Y, Abel J, Vetter H, Brüning T. NAD(P)H quinone oxidoredutase 1 codon 609 polymorphism and its association to colorectal cancer. Arch Toxicol 2000; 73: 528-531 IF: 6.100

022. *Thier R, Brüning T, Kocher K, Blaszkewicz M, Makropoulos V, Sundberg A, Bolt HM. Determination of urinary thymidine glycol using affinity chromatography, HPLC and post-column reaction detection: a biomarker of oxidative DNA damage upon kidney transplantation. Arch Toxicol 1999; 73: 479-484 IF: 6.100

021. *Brüning T, Abel J, Koch B, Lorenzen K, Harth V, Donat S, Sachinidis A, Vetter H, Bolt HM, Ko Y. Real-time PCR-analysis of the cytochrome P450 1B1 codon 432-polymorphism. Arch Toxicol 1999; 73: 427-430 IF: 6.100

020. *Schraml P, Zhaou M, Richter J, Brüning T, Pommer M, Sauter G, Mihatsch MJ, Moch H. Untersuchungen von Nierentumoren bei Trichlorethylen-exponierten Arbeitern mittels Comparative Genomic Hybridization und DNA Sequenzierung. Verh Dtsch Ges Path 1999; 83: 218-224

019. Thier R, Golka K, Brüning T, Bolt HM. Genetische Suszeptibilität im Hinblick auf toxische Arbeitsplatz- und Umweltbelastungen. Bundesgesundheitsblatt 1999 42: 834-840 IF: 1.700

018. *Thier R, Lewalter J, Kempkes M, Selinski S, Brüning T, Bolt HM. Haemoglobin adducts of acrylonitrile and ethylene oxide in acrylonitrile workers, dependent on polymorphisms of the glutathione transferases GSTT1 and GSTM1. Arch Toxicol 1999; 73: 197-202 IF: 6.100

017. *Fritsche E, Brüning T, Jonkmanns C, Ko Y, Bolt HM, Abel J. Detection of Cytochrome P450 1B1 BfrI polymorphism: genotype distribution in healthy Germans and in patients with colorectal carcinoma. Pharmacogenetics 1999; 9: 405-408 IF: 2.600

016. *Brüning T, Sundberg A, Birner G, Lammert M, Appelkvist EL, Nilsson R, Bolt HM, Dallner G. Glutathione transferase a as a marker for tubular damage after trichloroethylene exposure. Arch Toxicol 1999; 73: 246-254 IF: 6.100

015. *Brüning T, Mann H, Melzer H, Sundberg A, Bolt HM. Pathological excretion patterns of urinary proteins in renal cell cancer patients exposed to trichloroethylene. Occup Med 1999; 49: 299-305 IF: 5.100

014. *Brauch H, Weirich G, Störkel S, Hornauer MA, Wöhl T, Brüning T. Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma. J Natl Cancer Inst 1999; 91: 854-861 IF: 13.757

013. *Brüning T, Chronz C, Thier R, Havelka J, Ko Y, Bolt HM. Occurrence of urinary tract tumours in miners highly exposed to dinitrotoluene. J Occup Environ Med 1999; 41: 144-149 IF: 3.200

012. *Bantel H, Brüning T, Schulze-Osthoff K. Activation of caspases by death receptors. Eur Cytokine Netw 1998; 9: 681-684 IF: 2.800

011. *Thier R, Wiebel F, Hinkel A, Burger A, Brüning T, Morgenroth K, Senge T, Wilhelm M, Schulz T. Species differences in the glutathione transferase GSTT1-1 activity towards the model substrates methyl chloride and dichloromethane in the liver and kidney. Arch Toxicol 1998; 72: 622-629 IF: 6.100

010. *Vamvakas S, Brüning T, Thomas B, Lammert M, Baumüller A, Bolt HM, Dekant W, Birner G, Henschler D, Ulm K. Renal cell cancer correlated with occupational exposure to trichloroethene. J Cancer Res Clin Oncol 1998; 124: 374-382 IF: 3.600

009. *Bröde P, Brüning T, Griefahn B. Equivalent sensation curves of simultaneous lateral and vertical sinusoidal whole-body vibration. Aviat Space Envir Med 1998; 69: 986-991 IF: 0.933

008. *Brüning T, Vamvakas S, Makropoulos W, Birner G. Acute intoxication with trichloroethene: clinical symptoms, toxicokinetics, metabolism and development of biochemical parameters for renal damage. Toxicol Sci 1998; 41: 157-165 IF: 3.800 (ehemals Fund Appl Toxicol)

007. Golka K, Hartert-Raulf T, Schöps W, Kierfeld G, Brüning T, Bolt HM. Subclinical changes in urinary protein excretion of renal cell cancer patients: Effect of high occupational exposure to trichloroethylene. Centr Eur J Occup Med 1997; 3: 167-174

006. *Weirich G, Hornauer M, Brüning T, Höfler H, Brauch H. Fixed archival tissue: purify DNA and primers for good PCR yield. Mol Biotechnol 1997; 8: 299-302 IF: 2.600 (ehemals Appl Biochem Biotech)

005. Bröde P, Brüning T, Griefahn B. Äquivalente Wahrnehmung simultan einwirkender lateraler und vertikaler sinusförmiger Ganzkörperschwingungen. Z Arbeitswiss 1997; 51: 79-84

004. *Brüning T, Lammert M, Kempke, M, Thier R, Golka K, Bolt HM. Influence of Polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with a long-term and high occupational exposure to trichloroethene. Arch Toxicol 1997; 71: 596-599 IF: 6.100

003. *Brüning T, Weirich G, Hornauer M, Höfler H, Brauch H. Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumor suppressor gene. Arch Toxicol 1997; 71: 332-335, IF: 6.100

002.*Brüning T, Golka K, Makropoulos V, Bolt HM. Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethene. Arch Toxicol 1996; 70: 259-260 IF: 6.100

001. *Makropoulos V, Brüning T, Schulze-Osthoff K. Selenium-mediated inhibition of transcription factor NF-kB and HIV-1 LTR promoter activity. Arch Toxicol 1996; 70: 277-283 IF: 6.100